BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

319 related articles for article (PubMed ID: 16368709)

  • 1. Mitochondrial and nuclear DNA defects in Saccharomyces cerevisiae with mutations in DNA polymerase gamma associated with progressive external ophthalmoplegia.
    Stuart GR; Santos JH; Strand MK; Van Houten B; Copeland WC
    Hum Mol Genet; 2006 Jan; 15(2):363-74. PubMed ID: 16368709
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetic and chemical rescue of the Saccharomyces cerevisiae phenotype induced by mitochondrial DNA polymerase mutations associated with progressive external ophthalmoplegia in humans.
    Baruffini E; Lodi T; Dallabona C; Puglisi A; Zeviani M; Ferrero I
    Hum Mol Genet; 2006 Oct; 15(19):2846-55. PubMed ID: 16940310
    [TBL] [Abstract][Full Text] [Related]  

  • 3. mip1 containing mutations associated with mitochondrial disease causes mutagenesis and depletion of mtDNA in Saccharomyces cerevisiae.
    Stumpf JD; Bailey CM; Spell D; Stillwagon M; Anderson KS; Copeland WC
    Hum Mol Genet; 2010 Jun; 19(11):2123-33. PubMed ID: 20185557
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mitochondrial DNA defects in Saccharomyces cerevisiae caused by functional interactions between DNA polymerase gamma mutations associated with disease in human.
    Baruffini E; Ferrero I; Foury F
    Biochim Biophys Acta; 2007 Dec; 1772(11-12):1225-35. PubMed ID: 17980715
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Combined use of Saccharomyces cerevisiae, Caenorhabditis elegans and patient fibroblasts leads to the identification of clofilium tosylate as a potential therapeutic chemical against POLG-related diseases.
    Pitayu L; Baruffini E; Rodier C; Rötig A; Lodi T; Delahodde A
    Hum Mol Genet; 2016 Feb; 25(4):715-27. PubMed ID: 26692522
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Yeast model analysis of novel polymerase gamma variants found in patients with autosomal recessive mitochondrial disease.
    Kaliszewska M; Kruszewski J; Kierdaszuk B; Kostera-Pruszczyk A; Nojszewska M; Łusakowska A; Vizueta J; Sabat D; Lutyk D; Lower M; Piekutowska-Abramczuk D; Kaniak-Golik A; Pronicka E; Kamińska A; Bartnik E; Golik P; Tońska K
    Hum Genet; 2015 Sep; 134(9):951-66. PubMed ID: 26077851
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutation of POLG is associated with progressive external ophthalmoplegia characterized by mtDNA deletions.
    Van Goethem G; Dermaut B; Löfgren A; Martin JJ; Van Broeckhoven C
    Nat Genet; 2001 Jul; 28(3):211-2. PubMed ID: 11431686
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Progressive external ophthalmoplegia and multiple mitochondrial DNA deletions.
    Van Goethem G; Martin JJ; Van Broeckhoven C
    Acta Neurol Belg; 2002 Mar; 102(1):39-42. PubMed ID: 12094562
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Association of novel POLG mutations and multiple mitochondrial DNA deletions with variable clinical phenotypes in a Spanish population.
    González-Vioque E; Blázquez A; Fernández-Moreira D; Bornstein B; Bautista J; Arpa J; Navarro C; Campos Y; Fernández-Moreno MA; Garesse R; Arenas J; Martín MA
    Arch Neurol; 2006 Jan; 63(1):107-11. PubMed ID: 16401742
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: clinical and molecular genetic study.
    Luoma P; Melberg A; Rinne JO; Kaukonen JA; Nupponen NN; Chalmers RM; Oldfors A; Rautakorpi I; Peltonen L; Majamaa K; Somer H; Suomalainen A
    Lancet; 2004 Sep 4-10; 364(9437):875-82. PubMed ID: 15351195
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A cluster of pathogenic mutations in the 3'-5' exonuclease domain of DNA polymerase gamma defines a novel module coupling DNA synthesis and degradation.
    Szczepanowska K; Foury F
    Hum Mol Genet; 2010 Sep; 19(18):3516-29. PubMed ID: 20601675
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The clinical diagnosis of POLG disease and other mitochondrial DNA depletion disorders.
    Cohen BH; Naviaux RK
    Methods; 2010 Aug; 51(4):364-73. PubMed ID: 20558295
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutations in AAC2, equivalent to human adPEO-associated ANT1 mutations, lead to defective oxidative phosphorylation in Saccharomyces cerevisiae and affect mitochondrial DNA stability.
    Fontanesi F; Palmieri L; Scarcia P; Lodi T; Donnini C; Limongelli A; Tiranti V; Zeviani M; Ferrero I; Viola AM
    Hum Mol Genet; 2004 May; 13(9):923-34. PubMed ID: 15016764
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antimutator alleles of yeast DNA polymerase gamma modulate the balance between DNA synthesis and excision.
    Foury F; Szczepanowska K
    PLoS One; 2011; 6(11):e27847. PubMed ID: 22114710
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The unfolding clinical spectrum of POLG mutations.
    Blok MJ; van den Bosch BJ; Jongen E; Hendrickx A; de Die-Smulders CE; Hoogendijk JE; Brusse E; de Visser M; Poll-The BT; Bierau J; de Coo IF; Smeets HJ
    J Med Genet; 2009 Nov; 46(11):776-85. PubMed ID: 19578034
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The carboxyl-terminal extension on fungal mitochondrial DNA polymerases: identification of a critical region of the enzyme from Saccharomyces cerevisiae.
    Young MJ; Theriault SS; Li M; Court DA
    Yeast; 2006 Jan; 23(2):101-16. PubMed ID: 16491467
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Yeast cells expressing the human mitochondrial DNA polymerase reveal correlations between polymerase fidelity and human disease progression.
    Qian Y; Kachroo AH; Yellman CM; Marcotte EM; Johnson KA
    J Biol Chem; 2014 Feb; 289(9):5970-85. PubMed ID: 24398692
    [TBL] [Abstract][Full Text] [Related]  

  • 18. POLG mutations in sporadic mitochondrial disorders with multiple mtDNA deletions.
    Di Fonzo A; Bordoni A; Crimi M; Sara G; Del Bo R; Bresolin N; Comi GP
    Hum Mutat; 2003 Dec; 22(6):498-9. PubMed ID: 14635118
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MMS exposure promotes increased MtDNA mutagenesis in the presence of replication-defective disease-associated DNA polymerase γ variants.
    Stumpf JD; Copeland WC
    PLoS Genet; 2014 Oct; 10(10):e1004748. PubMed ID: 25340760
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Low frequency of mtDNA point mutations in patients with PEO associated with POLG1 mutations.
    Kollberg G; Jansson M; Pérez-Bercoff A; Melberg A; Lindberg C; Holme E; Moslemi AR; Oldfors A
    Eur J Hum Genet; 2005 Apr; 13(4):463-9. PubMed ID: 15702133
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.