BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

109 related articles for article (PubMed ID: 1637820)

  • 1. Purification of human S-adenosylmethionine decarboxylase expressed in Escherichia coli and use of this protein to investigate the mechanism of inhibition by the irreversible inhibitors, 5'-deoxy-5'-[(3-hydrazinopropyl)methylamino]adenosine and 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine.
    Shantz LM; Stanley BA; Secrist JA; Pegg AE
    Biochemistry; 1992 Jul; 31(29):6848-55. PubMed ID: 1637820
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Irreversible inhibition of rat S-adenosylmethionine decarboxylase by 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine.
    Danzin C; Marchal P; Casara P
    Biochem Pharmacol; 1990 Oct; 40(7):1499-503. PubMed ID: 2222506
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Polyamine-mediated regulation of S-adenosylmethionine decarboxylase expression in mammalian cells. Studies using 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine, a suicide inhibitor of the enzyme.
    Stjernborg L; Heby O; Mamont P; Persson L
    Eur J Biochem; 1993 Jun; 214(3):671-6. PubMed ID: 8319678
    [TBL] [Abstract][Full Text] [Related]  

  • 4. S-adenosylmethionine decarboxylase as an enzyme target for therapy.
    Pegg AE; McCann PP
    Pharmacol Ther; 1992 Dec; 56(3):359-77. PubMed ID: 1301596
    [TBL] [Abstract][Full Text] [Related]  

  • 5. S-adenosylmethionine decarboxylase from Leishmania donovani. Molecular, genetic, and biochemical characterization of null mutants and overproducers.
    Roberts SC; Scott J; Gasteier JE; Jiang Y; Brooks B; Jardim A; Carter NS; Heby O; Ullman B
    J Biol Chem; 2002 Feb; 277(8):5902-9. PubMed ID: 11734561
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of chronic 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxy- adenosine (AbeAdo) treatment on polyamine and eIF-5A metabolism in AbeAdo-sensitive and -resistant L1210 murine leukaemia cells.
    Byers TL; Wiest L; Wechter RS; Pegg AE
    Biochem J; 1993 Feb; 290 ( Pt 1)(Pt 1):115-21. PubMed ID: 8439281
    [TBL] [Abstract][Full Text] [Related]  

  • 7. S-adenosylmethionine decarboxylase degradation by the 26 S proteasome is accelerated by substrate-mediated transamination.
    Yerlikaya A; Stanley BA
    J Biol Chem; 2004 Mar; 279(13):12469-78. PubMed ID: 14718534
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Trypanosoma cruzi has not lost its S-adenosylmethionine decarboxylase: characterization of the gene and the encoded enzyme.
    Persson K; Aslund L; Grahn B; Hanke J; Heby O
    Biochem J; 1998 Aug; 333 ( Pt 3)(Pt 3):527-37. PubMed ID: 9677309
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of inhibitors of S-adenosylmethionine decarboxylase on polyamine content and growth of L1210 cells.
    Pegg AE; Jones DB; Secrist JA
    Biochemistry; 1988 Mar; 27(5):1408-15. PubMed ID: 3365395
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Spermidine biosynthesis in Saccharomyces cerevisiae. Biosynthesis and processing of a proenzyme form of S-adenosylmethionine decarboxylase.
    Kashiwagi K; Taneja SK; Liu TY; Tabor CW; Tabor H
    J Biol Chem; 1990 Dec; 265(36):22321-8. PubMed ID: 2266128
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and evaluation of analogs of 5'-(((Z)-4-amino-2-butenyl)methylamino)-5'-deoxyadenosine (MDL 73811, or AbeAdo) - An inhibitor of S-adenosylmethionine decarboxylase with antitrypanosomal activity.
    Brockway AJ; Volkov OA; Cosner CC; MacMillan KS; Wring SA; Richardson TE; Peel M; Phillips MA; De Brabander JK
    Bioorg Med Chem; 2017 Oct; 25(20):5433-5440. PubMed ID: 28807574
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cytostasis induced in L1210 murine leukaemia cells by the S-adenosyl-L-methionine decarboxylase inhibitor 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine may be due to hypusine depletion.
    Byers TL; Ganem B; Pegg AE
    Biochem J; 1992 Nov; 287 ( Pt 3)(Pt 3):717-24. PubMed ID: 1445235
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Overproduction of S-adenosylmethionine decarboxylase in ethylglyoxal-bis(guanylhydrazone)-resistant mouse FM3A cells.
    Suzuki T; Sadakata Y; Kashiwagi K; Hoshino K; Kakinuma Y; Shirahata A; Igarashi K
    Eur J Biochem; 1993 Jul; 215(2):247-53. PubMed ID: 8344293
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of the S-adenosylmethionine decarboxylase inhibitor, 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine, on cell growth and polyamine metabolism and transport in Chinese hamster ovary cell cultures.
    Byers TL; Wechter RS; Hu RH; Pegg AE
    Biochem J; 1994 Oct; 303 ( Pt 1)(Pt 1):89-96. PubMed ID: 7945270
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Site of pyruvate formation and processing of mammalian S-adenosylmethionine decarboxylase proenzyme.
    Stanley BA; Pegg AE; Holm I
    J Biol Chem; 1989 Dec; 264(35):21073-9. PubMed ID: 2687270
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 4-Amidinoindan-1-one 2'-amidinohydrazone (CGP 48664A) exerts in vitro growth inhibitory effects that are not only related to S-adenosylmethionine decarboxylase (SAMdc) inhibition.
    Dorhout B; Odink MF; de Hoog E; Kingma AW; van der Veer E; Muskiet FA
    Biochim Biophys Acta; 1997 Apr; 1335(1-2):144-52. PubMed ID: 9133651
    [TBL] [Abstract][Full Text] [Related]  

  • 17. S-(5'-deoxy-5'-adenosyl)-1-ammonio-4-(methylsulfonio)-2-cyclopentene: A potent, enzyme-activated irreversible inhibitor of S-adenosylmethionine decarboxylase.
    Wu Y; Woster PM
    J Med Chem; 1992 Aug; 35(17):3196-201. PubMed ID: 1507205
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Putrescine activated S-adenosylmethionine decarboxylase from Trypanosoma brucei brucei.
    Tekwani BL; Bacchi CJ; Pegg AE
    Mol Cell Biochem; 1992 Nov; 117(1):53-61. PubMed ID: 1480164
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase.
    Tolbert WD; Ekstrom JL; Mathews II; Secrist JA; Kapoor P; Pegg AE; Ealick SE
    Biochemistry; 2001 Aug; 40(32):9484-94. PubMed ID: 11583147
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression of mammalian S-adenosylmethionine decarboxylase in Escherichia coli. Determination of sites for putrescine activation of activity and processing.
    Stanley BA; Shantz LM; Pegg AE
    J Biol Chem; 1994 Mar; 269(11):7901-7. PubMed ID: 8132508
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.