BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

95 related articles for article (PubMed ID: 16380120)

  • 1. The translocation mechanism of P-glycoprotein.
    Callaghan R; Ford RC; Kerr ID
    FEBS Lett; 2006 Feb; 580(4):1056-63. PubMed ID: 16380120
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stimulation of P-glycoprotein ATPase by analogues of tetramethylrosamine: coupling of drug binding at the "R" site to the ATP hydrolysis transition state.
    Tombline G; Donnelly DJ; Holt JJ; You Y; Ye M; Gannon MK; Nygren CL; Detty MR
    Biochemistry; 2006 Jul; 45(26):8034-47. PubMed ID: 16800628
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The coupling mechanism of P-glycoprotein involves residue L339 in the sixth membrane spanning segment.
    Rothnie A; Storm J; McMahon R; Taylor A; Kerr ID; Callaghan R
    FEBS Lett; 2005 Jul; 579(18):3984-90. PubMed ID: 16004994
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cholesterol interaction with the daunorubicin binding site of P-glycoprotein.
    Wang E; Casciano CN; Clement RP; Johnson WW
    Biochem Biophys Res Commun; 2000 Oct; 276(3):909-16. PubMed ID: 11027568
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modulator-induced interference in functional cross talk between the substrate and the ATP sites of human P-glycoprotein.
    Maki N; Moitra K; Silver C; Ghosh P; Chattopadhyay A; Dey S
    Biochemistry; 2006 Feb; 45(8):2739-51. PubMed ID: 16489767
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interaction of tomato lectin with ABC transporter in cancer cells: glycosylation confers functional conformation of P-gp.
    Molnár J; Kars MD; Gündüz U; Engi H; Schumacher U; Van Damme EJ; Peumans WJ; Makovitzky J; Gyémánt N; Molnár P
    Acta Histochem; 2009; 111(4):329-33. PubMed ID: 19124148
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The power of the pump: mechanisms of action of P-glycoprotein (ABCB1).
    Ambudkar SV; Kim IW; Sauna ZE
    Eur J Pharm Sci; 2006 Apr; 27(5):392-400. PubMed ID: 16352426
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ATP hydrolysis promotes interactions between the extracellular ends of transmembrane segments 1 and 11 of human multidrug resistance P-glycoprotein.
    Loo TW; Bartlett MC; Clarke DM
    Biochemistry; 2005 Aug; 44(30):10250-8. PubMed ID: 16042402
    [TBL] [Abstract][Full Text] [Related]  

  • 9. P-glycoprotein enhances TRAIL-triggered apoptosis in multidrug resistant cancer cells by interacting with the death receptor DR5.
    Park SJ; Wu CH; Choi MR; Najafi F; Emami A; Safa AR
    Biochem Pharmacol; 2006 Jul; 72(3):293-307. PubMed ID: 16753135
    [TBL] [Abstract][Full Text] [Related]  

  • 10. P-Glycoprotein (P-gp) expressed in a confluent monolayer of hMDR1-MDCKII cells has more than one efflux pathway with cooperative binding sites.
    Acharya P; Tran TT; Polli JW; Ayrton A; Ellens H; Bentz J
    Biochemistry; 2006 Dec; 45(51):15505-19. PubMed ID: 17176072
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanistic differences between GSH transport by multidrug resistance protein 1 (MRP1/ABCC1) and GSH modulation of MRP1-mediated transport.
    Rothnie A; Conseil G; Lau AY; Deeley RG; Cole SP
    Mol Pharmacol; 2008 Dec; 74(6):1630-40. PubMed ID: 18768387
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nucleotide binding, ATP hydrolysis, and mutation of the catalytic carboxylates of human P-glycoprotein cause distinct conformational changes in the transmembrane segments.
    Loo TW; Bartlett MC; Clarke DM
    Biochemistry; 2007 Aug; 46(32):9328-36. PubMed ID: 17636884
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Do drug substrates enter the common drug-binding pocket of P-glycoprotein through "gates"?
    Loo TW; Clarke DM
    Biochem Biophys Res Commun; 2005 Apr; 329(2):419-22. PubMed ID: 15737603
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bivalent probes of the human multidrug transporter P-glycoprotein.
    Pires MM; Hrycyna CA; Chmielewski J
    Biochemistry; 2006 Sep; 45(38):11695-702. PubMed ID: 16981729
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure of the multidrug resistance P-glycoprotein.
    Higgins CF; Callaghan R; Linton KJ; Rosenberg MF; Ford RC
    Semin Cancer Biol; 1997 Jun; 8(3):135-42. PubMed ID: 9441943
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Residue G346 in transmembrane segment six is involved in inter-domain communication in P-glycoprotein.
    Storm J; O'Mara ML; Crowley EH; Peall J; Tieleman DP; Kerr ID; Callaghan R
    Biochemistry; 2007 Sep; 46(35):9899-910. PubMed ID: 17696319
    [TBL] [Abstract][Full Text] [Related]  

  • 17. P-glycoprotein related drug interactions: clinical importance and a consideration of disease states.
    Lee CA; Cook JA; Reyner EL; Smith DA
    Expert Opin Drug Metab Toxicol; 2010 May; 6(5):603-19. PubMed ID: 20397967
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Multidrug transporters from bacteria to man: similarities in structure and function.
    van Veen HW; Konings WN
    Semin Cancer Biol; 1997 Jun; 8(3):183-91. PubMed ID: 9441947
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Providing a molecular mechanism for P-glycoprotein; why would I bother?
    Callaghan R
    Biochem Soc Trans; 2015 Oct; 43(5):995-1002. PubMed ID: 26517914
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tariquidar (XR9576): a P-glycoprotein drug efflux pump inhibitor.
    Fox E; Bates SE
    Expert Rev Anticancer Ther; 2007 Apr; 7(4):447-59. PubMed ID: 17428165
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.