These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

308 related articles for article (PubMed ID: 16380470)

  • 1. The network of glucokinase-expressing cells in glucose homeostasis and the potential of glucokinase activators for diabetes therapy.
    Matschinsky FM; Magnuson MA; Zelent D; Jetton TL; Doliba N; Han Y; Taub R; Grimsby J
    Diabetes; 2006 Jan; 55(1):1-12. PubMed ID: 16380470
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Research and development of glucokinase activators for diabetes therapy: theoretical and practical aspects.
    Matschinsky FM; Zelent B; Doliba NM; Kaestner KH; Vanderkooi JM; Grimsby J; Berthel SJ; Sarabu R
    Handb Exp Pharmacol; 2011; (203):357-401. PubMed ID: 21484579
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glucokinase and glucose homeostasis: proven concepts and new ideas.
    Zelent D; Najafi H; Odili S; Buettger C; Weik-Collins H; Li C; Doliba N; Grimsby J; Matschinsky FM
    Biochem Soc Trans; 2005 Feb; 33(Pt 1):306-10. PubMed ID: 15667334
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Small molecule glucokinase activators as novel anti-diabetic agents.
    Leighton B; Atkinson A; Coghlan MP
    Biochem Soc Trans; 2005 Apr; 33(Pt 2):371-4. PubMed ID: 15787609
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Recent advances in glucokinase activators for the treatment of type 2 diabetes.
    Pal M
    Drug Discov Today; 2009 Aug; 14(15-16):784-92. PubMed ID: 19520181
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase.
    Kamata K; Mitsuya M; Nishimura T; Eiki J; Nagata Y
    Structure; 2004 Mar; 12(3):429-38. PubMed ID: 15016359
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A report of 2 new cases of MODY2 and review of the literature: implications in the search for type 2 diabetes drugs.
    Shammas C; Neocleous V; Phelan MM; Lian LY; Skordis N; Phylactou LA
    Metabolism; 2013 Nov; 62(11):1535-42. PubMed ID: 23890519
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Recent updates on glucokinase activators for the treatment of type 2 diabetes mellitus.
    Grewal AS; Sekhon BS; Lather V
    Mini Rev Med Chem; 2014; 14(7):585-602. PubMed ID: 25052034
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel glucokinase activators: a patent review (2008 - 2010).
    Sarabu R; Berthel SJ; Kester RF; Tilley JW
    Expert Opin Ther Pat; 2011 Jan; 21(1):13-33. PubMed ID: 21155690
    [TBL] [Abstract][Full Text] [Related]  

  • 10. GKAs for diabetes therapy: why no clinically useful drug after two decades of trying?
    Matschinsky FM
    Trends Pharmacol Sci; 2013 Feb; 34(2):90-9. PubMed ID: 23305809
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel, highly potent systemic glucokinase activators for the treatment of Type 2 Diabetes Mellitus.
    Xu J; Lin S; Myers RW; Addona G; Berger JP; Campbell B; Chen HS; Chen Z; Eiermann GJ; Elowe NH; Farrer BT; Feng W; Fu Q; Kats-Kagan R; Kavana M; Malkani S; McMasters DR; Mitra K; Pachanski MJ; Tong X; Trujillo ME; Xu L; Zhang B; Zhang F; Zhang R; Parmee ER
    Bioorg Med Chem Lett; 2017 May; 27(9):2069-2073. PubMed ID: 28284804
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular modeling and identification of novel glucokinase activators through stepwise virtual screening.
    Behera PM; Behera DK; Satpati S; Agnihotri G; Nayak S; Padhi P; Dixit A
    J Mol Graph Model; 2015 Apr; 57():122-30. PubMed ID: 25723349
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Glucokinase-activating ureas.
    Castelhano AL; Dong H; Fyfe MC; Gardner LS; Kamikozawa Y; Kurabayashi S; Nawano M; Ohashi R; Procter MJ; Qiu L; Rasamison CM; Schofield KL; Shah VK; Ueta K; Williams GM; Witter D; Yasuda K
    Bioorg Med Chem Lett; 2005 Mar; 15(5):1501-4. PubMed ID: 15713416
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reversal of type 1 diabetes by engineering a glucose sensor in skeletal muscle.
    Mas A; Montané J; Anguela XM; Muñoz S; Douar AM; Riu E; Otaegui P; Bosch F
    Diabetes; 2006 Jun; 55(6):1546-53. PubMed ID: 16731816
    [TBL] [Abstract][Full Text] [Related]  

  • 15. From clinicogenetic studies of maturity-onset diabetes of the young to unraveling complex mechanisms of glucokinase regulation.
    Sagen JV; Odili S; Bjørkhaug L; Zelent D; Buettger C; Kwagh J; Stanley C; Dahl-Jørgensen K; de Beaufort C; Bell GI; Han Y; Grimsby J; Taub R; Molven A; Søvik O; Njølstad PR; Matschinsky FM
    Diabetes; 2006 Jun; 55(6):1713-22. PubMed ID: 16731834
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm.
    Matschinsky FM
    Diabetes; 1996 Feb; 45(2):223-41. PubMed ID: 8549869
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Glucokinase activators in diabetes management.
    Coghlan M; Leighton B
    Expert Opin Investig Drugs; 2008 Feb; 17(2):145-67. PubMed ID: 18230050
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Small molecule glucokinase activators as glucose lowering agents: a new paradigm for diabetes therapy.
    Guertin KR; Grimsby J
    Curr Med Chem; 2006; 13(15):1839-43. PubMed ID: 16787225
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The potential role of glucokinase activator SHP289-04 in anti-diabetes and hepatic protection.
    Lei L; Liu S; Li Y; Song H; He L; Liu Q; Sun S; Li Y; Feng Z; Shen Z
    Eur J Pharmacol; 2018 May; 826():17-23. PubMed ID: 29477658
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutants of glucokinase cause hypoglycaemia- and hyperglycaemia syndromes and their analysis illuminates fundamental quantitative concepts of glucose homeostasis.
    Davis EA; Cuesta-Muñoz A; Raoul M; Buettger C; Sweet I; Moates M; Magnuson MA; Matschinsky FM
    Diabetologia; 1999 Oct; 42(10):1175-86. PubMed ID: 10525657
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.