BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 16384700)

  • 1. Novel lactam NK1 antagonists with anti-emetic activity.
    Hollingworth GJ; Carlson EJ; Castro JL; Chicchi GG; Clark N; Cooper LC; Dirat O; Salvo JD; Elliott JM; Kilburn R; Kurtz MM; Rycroft W; Tattersall FD; Tsao KL; Swain CJ
    Bioorg Med Chem Lett; 2006 Mar; 16(5):1197-201. PubMed ID: 16384700
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of novel NK1/NK3 dual antagonists for the potential treatment of schizophrenia.
    Catalani MP; Alvaro G; Bernasconi G; Bettini E; Bromidge SM; Heer J; Tedesco G; Tommasi S
    Bioorg Med Chem Lett; 2011 Nov; 21(22):6899-904. PubMed ID: 21974957
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of a novel, potent and orally active series of gamma-lactams as selective NK1 antagonists.
    Paliwal S; Reichard GA; Shah S; Wrobleski ML; Wang C; Stengone C; Tsui HC; Xiao D; Duffy RA; Lachowicz JE; Nomeir AA; Varty GB; Shih NY
    Bioorg Med Chem Lett; 2008 Jul; 18(14):4168-71. PubMed ID: 18547807
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NK1 antagonists based on seven membered lactam scaffolds.
    Elliott JM; Carlson EJ; Chicchi GG; Dirat O; Dominguez M; Gerhard U; Jelley R; Jones AB; Kurtz MM; Tsao Kl; Wheeldon A
    Bioorg Med Chem Lett; 2006 Jun; 16(11):2929-32. PubMed ID: 16574413
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery and stereoselective synthesis of the novel isochroman neurokinin-1 receptor antagonist 'CJ-17,493'.
    Shishido Y; Wakabayashi H; Koike H; Ueno N; Nukui S; Yamagishi T; Murata Y; Naganeo F; Mizutani M; Shimada K; Fujiwara Y; Sakakibara A; Suga O; Kusano R; Ueda S; Kanai Y; Tsuchiya M; Satake K
    Bioorg Med Chem; 2008 Aug; 16(15):7193-205. PubMed ID: 18640044
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and structure-activity relationships of novel pyrrolocarbazole lactam analogs as potent and cell-permeable inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1).
    Wells GJ; Bihovsky R; Hudkins RL; Ator MA; Husten J
    Bioorg Med Chem Lett; 2006 Mar; 16(5):1151-5. PubMed ID: 16359865
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tetrahydroindolizinone NK1 antagonists.
    Bao J; Lu H; Morriello GJ; Carlson EJ; Wheeldon A; Chicchi GG; Kurtz MM; Tsao KL; Zheng S; Tong X; Mills SG; DeVita RJ
    Bioorg Med Chem Lett; 2010 Apr; 20(7):2354-8. PubMed ID: 20188553
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Neurokinin 1 receptor antagonists--current prospects.
    Alvaro G; Di Fabio R
    Curr Opin Drug Discov Devel; 2007 Sep; 10(5):613-21. PubMed ID: 17786860
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cyclic urea derivatives as potent NK1 selective antagonists.
    Shue HJ; Chen X; Shih NY; Blythin DJ; Paliwal S; Lin L; Gu D; Schwerdt JH; Shah S; Reichard GA; Piwinski JJ; Duffy RA; Lachowicz JE; Coffin VL; Liu F; Nomeir AA; Morgan CA; Varty GB
    Bioorg Med Chem Lett; 2005 Sep; 15(17):3896-9. PubMed ID: 16019209
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-activity relationship studies on vitamin D lactam derivatives as vitamin D receptor antagonist.
    Cho K; Uneuchi F; Kato-Nakamura Y; Namekawa J; Ishizuka S; Takenouchi K; Nagasawa K
    Bioorg Med Chem Lett; 2008 Aug; 18(15):4287-90. PubMed ID: 18635349
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modification of cap group in delta-lactam-based histone deacetylase (HDAC) inhibitors.
    Kim HM; Hong SH; Kim MS; Lee CW; Kang JS; Lee K; Park SK; Han JW; Lee HY; Choi Y; Kwon HJ; Han G
    Bioorg Med Chem Lett; 2007 Nov; 17(22):6234-8. PubMed ID: 17904843
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-activity relationship studies of a series of novel delta-lactam-based histone deacetylase inhibitors.
    Kim HM; Ryu DK; Choi Y; Park BW; Lee K; Han SB; Lee CW; Kang MR; Kang JS; Boovanahalli SK; Park SK; Han JW; Chun TG; Lee HY; Nam KY; Choi EH; Han G
    J Med Chem; 2007 May; 50(11):2737-41. PubMed ID: 17477518
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, characterization, and anti-bacterial efficacy of some novel cyclophane amide.
    Rajakumar P; Rasheed AM; Balu PM; Murugesan K
    Bioorg Med Chem; 2006 Nov; 14(22):7458-67. PubMed ID: 16879971
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Preparation of highly substituted gamma-lactam follicle stimulating hormone receptor agonists.
    Pelletier JC; Rogers J; Wrobel J; Perez MC; Shen ES
    Bioorg Med Chem; 2005 Nov; 13(21):5986-95. PubMed ID: 16099664
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cyclic urea derivatives as potent NK1 selective antagonists. Part II: Effects of fluoro and benzylic methyl substitutions.
    Shue HJ; Chen X; Schwerdt JH; Paliwal S; Blythin DJ; Lin L; Gu D; Wang C; Reichard GA; Wang H; Piwinski JJ; Duffy RA; Lachowicz JE; Coffin VL; Nomeir AA; Morgan CA; Varty GB; Shih NY
    Bioorg Med Chem Lett; 2006 Feb; 16(4):1065-9. PubMed ID: 16290143
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 4,4-Disubstituted cyclohexylamine NK(1) receptor antagonists I.
    Elliott JM; Castro JL; Chicchi GG; Cooper LC; Dinnell K; Hollingworth GJ; Ridgill MP; Rycroft W; Kurtz MM; Shaw DE; Swain CJ; Tsao KL; Yang L
    Bioorg Med Chem Lett; 2002 Jul; 12(13):1755-8. PubMed ID: 12067554
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Study of the intramolecular cyclization of N-methyl-3-phenyl-N-(2-(E)-phenylethenyl)-trans(cis)-oxiranecarboxamide--syntheses of Homoclausenamide and Dehydroclausenamide.
    Ma N; Wu K; Huang L
    Eur J Med Chem; 2008 Aug; 43(8):1781-4. PubMed ID: 18191305
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of a new series of non-peptidic NK3 receptor antagonists.
    Juhl K; Hansen T; Kehler J; Khanzhin NA; Nørgaard MB; Ruhland T; Larsen DB; Jensen KG; Steiniger-Brach B; Nielsen SM; Simonsen KB
    Bioorg Med Chem Lett; 2011 Mar; 21(5):1498-501. PubMed ID: 21292483
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural analysis and optimization of NK(1) receptor antagonists through modulation of atropisomer interconversion properties.
    Albert JS; Ohnmacht C; Bernstein PR; Rumsey WL; Aharony D; Alelyunas Y; Russell DJ; Potts W; Sherwood SA; Shen L; Dedinas RF; Palmer WE; Russell K
    J Med Chem; 2004 Jan; 47(3):519-29. PubMed ID: 14736234
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of diphenyl lactam derivatives as N-type calcium channel blockers.
    Doherty GA; Bhatia P; Vortherms TA; Marsh KC; Wetter JM; Mack H; Scott VE; Jarvis MF; Stewart AO
    Bioorg Med Chem Lett; 2012 Feb; 22(4):1716-8. PubMed ID: 22277280
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.