BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

673 related articles for article (PubMed ID: 16385450)

  • 1. Determinants of exon 7 splicing in the spinal muscular atrophy genes, SMN1 and SMN2.
    Cartegni L; Hastings ML; Calarco JA; de Stanchina E; Krainer AR
    Am J Hum Genet; 2006 Jan; 78(1):63-77. PubMed ID: 16385450
    [TBL] [Abstract][Full Text] [Related]  

  • 2. hnRNP A1 functions with specificity in repression of SMN2 exon 7 splicing.
    Kashima T; Rao N; David CJ; Manley JL
    Hum Mol Genet; 2007 Dec; 16(24):3149-59. PubMed ID: 17884807
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy.
    Kashima T; Manley JL
    Nat Genet; 2003 Aug; 34(4):460-3. PubMed ID: 12833158
    [TBL] [Abstract][Full Text] [Related]  

  • 4. hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1.
    Hofmann Y; Wirth B
    Hum Mol Genet; 2002 Aug; 11(17):2037-49. PubMed ID: 12165565
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An extended inhibitory context causes skipping of exon 7 of SMN2 in spinal muscular atrophy.
    Singh NN; Androphy EJ; Singh RN
    Biochem Biophys Res Commun; 2004 Mar; 315(2):381-8. PubMed ID: 14766219
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1.
    Cartegni L; Krainer AR
    Nat Genet; 2002 Apr; 30(4):377-84. PubMed ID: 11925564
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Splicing of a critical exon of human Survival Motor Neuron is regulated by a unique silencer element located in the last intron.
    Singh NK; Singh NN; Androphy EJ; Singh RN
    Mol Cell Biol; 2006 Feb; 26(4):1333-46. PubMed ID: 16449646
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Htra2-beta 1 stimulates an exonic splicing enhancer and can restore full-length SMN expression to survival motor neuron 2 (SMN2).
    Hofmann Y; Lorson CL; Stamm S; Androphy EJ; Wirth B
    Proc Natl Acad Sci U S A; 2000 Aug; 97(17):9618-23. PubMed ID: 10931943
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evolving concepts on human SMN pre-mRNA splicing.
    Singh RN
    RNA Biol; 2007; 4(1):7-10. PubMed ID: 17592254
    [TBL] [Abstract][Full Text] [Related]  

  • 10. hnRNP M facilitates exon 7 inclusion of SMN2 pre-mRNA in spinal muscular atrophy by targeting an enhancer on exon 7.
    Cho S; Moon H; Loh TJ; Oh HK; Cho S; Choy HE; Song WK; Chun JS; Zheng X; Shen H
    Biochim Biophys Acta; 2014; 1839(4):306-15. PubMed ID: 24533984
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 5-(N-ethyl-N-isopropyl)-amiloride enhances SMN2 exon 7 inclusion and protein expression in spinal muscular atrophy cells.
    Yuo CY; Lin HH; Chang YS; Yang WK; Chang JG
    Ann Neurol; 2008 Jan; 63(1):26-34. PubMed ID: 17924536
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1.
    Young PJ; DiDonato CJ; Hu D; Kothary R; Androphy EJ; Lorson CL
    Hum Mol Genet; 2002 Mar; 11(5):577-87. PubMed ID: 11875052
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An intronic element contributes to splicing repression in spinal muscular atrophy.
    Kashima T; Rao N; Manley JL
    Proc Natl Acad Sci U S A; 2007 Feb; 104(9):3426-31. PubMed ID: 17307868
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The RNA binding protein hnRNP Q modulates the utilization of exon 7 in the survival motor neuron 2 (SMN2) gene.
    Chen HH; Chang JG; Lu RM; Peng TY; Tarn WY
    Mol Cell Biol; 2008 Nov; 28(22):6929-38. PubMed ID: 18794368
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Seemingly neutral polymorphic variants may confer immunity to splicing-inactivating mutations: a synonymous SNP in exon 5 of MCAD protects from deleterious mutations in a flanking exonic splicing enhancer.
    Nielsen KB; Sørensen S; Cartegni L; Corydon TJ; Doktor TK; Schroeder LD; Reinert LS; Elpeleg O; Krainer AR; Gregersen N; Kjems J; Andresen BS
    Am J Hum Genet; 2007 Mar; 80(3):416-32. PubMed ID: 17273963
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy.
    Lorson CL; Hahnen E; Androphy EJ; Wirth B
    Proc Natl Acad Sci U S A; 1999 May; 96(11):6307-11. PubMed ID: 10339583
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SMN transcript stability: could modulation of messenger RNA degradation provide a novel therapy for spinal muscular atrophy?
    Heier CR; Gogliotti RG; DiDonato CJ
    J Child Neurol; 2007 Aug; 22(8):1013-8. PubMed ID: 17761657
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The regulation and regulatory activities of alternative splicing of the SMN gene.
    Singh NN; Androphy EJ; Singh RN
    Crit Rev Eukaryot Gene Expr; 2004; 14(4):271-85. PubMed ID: 15663357
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Spinal muscular atrophy: SMN2 pre-mRNA splicing corrected by a U7 snRNA derivative carrying a splicing enhancer sequence.
    Marquis J; Meyer K; Angehrn L; Kämpfer SS; Rothen-Rutishauser B; Schümperli D
    Mol Ther; 2007 Aug; 15(8):1479-86. PubMed ID: 17505471
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Correction of SMN2 Pre-mRNA splicing by antisense U7 small nuclear RNAs.
    Madocsai C; Lim SR; Geib T; Lam BJ; Hertel KJ
    Mol Ther; 2005 Dec; 12(6):1013-22. PubMed ID: 16226920
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.