105 related articles for article (PubMed ID: 1638672)
1. Acetoxime is metabolized by human and rodent hepatic cytochrome P450 enzymes to the genotoxicant and carcinogen propane 2-nitronate.
Kohl C; Schiller CD; Gescher A; Farmer PB; Bailey E
Carcinogenesis; 1992 Jul; 13(7):1091-4. PubMed ID: 1638672
[TBL] [Abstract][Full Text] [Related]
2. Slow oxidation of acetoxime and methylethyl ketoxime to the corresponding nitronates and hydroxy nitronates by liver microsomes from rats, mice, and humans.
Völkel W; Wolf N; Derelanko M; Dekant W
Toxicol Sci; 1999 Feb; 47(2):144-50. PubMed ID: 10220850
[TBL] [Abstract][Full Text] [Related]
3. Oxidative denitrification of 2-nitropropane and propane-2-nitronate by mouse liver microsomes: lack of correlation with hepatocytotoxic potential.
Dayal R; Goodwin B; Linhart I; Mynett K; Gescher A
Chem Biol Interact; 1991; 79(1):103-14. PubMed ID: 2060036
[TBL] [Abstract][Full Text] [Related]
4. Catalysis of nitro-aci tautomerism of the genotoxicant 2-nitropropane by cytosol from rodent and human liver.
Kohl C; Gescher A
Chem Biol Interact; 1996 Jan; 99(1-3):219-26. PubMed ID: 8620570
[TBL] [Abstract][Full Text] [Related]
5. Metabolism of the genotoxicant 2-nitropropane to a nitric oxide species.
Kohl C; Morgan P; Gescher A
Chem Biol Interact; 1995 Jul; 97(2):175-84. PubMed ID: 7606815
[TBL] [Abstract][Full Text] [Related]
6. Human phenol sulfotransferases hP-PST and hM-PST activate propane 2-nitronate to a genotoxicant.
Kreis P; Brandner S; Coughtrie MW; Pabel U; Meinl W; Glatt H; Andrae U
Carcinogenesis; 2000 Feb; 21(2):295-9. PubMed ID: 10657971
[TBL] [Abstract][Full Text] [Related]
7. Oxidative DNA and RNA damage in rat liver due to acetoxime: similarity to effects of 2-nitropropane.
Hussain NS; Conaway CC; Guo N; Asaad W; Fiala ES
Carcinogenesis; 1990 Jun; 11(6):1013-6. PubMed ID: 1693319
[TBL] [Abstract][Full Text] [Related]
8. Denitrification of the genotoxicant 2-nitropropane: relationship to its mechanism of toxicity.
Kohl C; Gescher A
Xenobiotica; 1997 Aug; 27(8):843-52. PubMed ID: 9293620
[TBL] [Abstract][Full Text] [Related]
9. Propane 2-nitronate is the major genotoxic form of 2-nitropropane.
Kohl C; Mynett K; Davies JE; Gescher A; Chipman JK
Mutat Res; 1994 Apr; 321(1-2):65-72. PubMed ID: 7510846
[TBL] [Abstract][Full Text] [Related]
10. Investigation of the chemical basis of nitroalkane toxicity: tautomerism and decomposition of propane 1- and 2-nitronate under physiological conditions.
Linhart I; Gescher A; Goodwin B
Chem Biol Interact; 1991; 80(2):187-201. PubMed ID: 1934149
[TBL] [Abstract][Full Text] [Related]
11. Sex and organ differences in oxidative DNA and RNA damage due to treatment of Sprague-Dawley rats with acetoxime or 2-nitropropane.
Guo N; Conaway CC; Hussain NS; Fiala ES
Carcinogenesis; 1990 Sep; 11(9):1659-62. PubMed ID: 1698128
[TBL] [Abstract][Full Text] [Related]
12. Activation of the liver carcinogen 2-nitropropane by aryl sulfotransferase.
Sodum RS; Sohn OS; Nie G; Fiala ES
Chem Res Toxicol; 1994; 7(3):344-51. PubMed ID: 7521230
[TBL] [Abstract][Full Text] [Related]
13. Propane 2-nitronate is more rapidly denitrified and is more genotoxic than 2-nitropropane in cultured rat hepatoma cells.
Dalke C; Andrae U
Toxicol Lett; 1992 Jul; 61(2-3):149-57. PubMed ID: 1641862
[TBL] [Abstract][Full Text] [Related]
14. Activation of propane 2-nitronate to a genotoxicant in V79-derived cell lines engineered for the expression of rat hepatic sulfotransferases.
Andrae U; Kreis P; Coughtrie MW; Pabel U; Meinl W; Bartsch I; Glatt H
Mutat Res; 1999 Feb; 439(2):191-7. PubMed ID: 10023057
[TBL] [Abstract][Full Text] [Related]
15. Amination of tyrosine in liver cytosol protein of male F344 rats treated with 2-nitropropane, 2-nitrobutane, 3-nitropentane, or acetoxime.
Sodum RS; Fiala ES
Chem Res Toxicol; 1997 Dec; 10(12):1420-6. PubMed ID: 9437534
[TBL] [Abstract][Full Text] [Related]
16. 2-Nitropropane induces DNA repair synthesis in rat hepatocytes in vitro and in vivo.
Andrae U; Homfeldt H; Vogl L; Lichtmannegger J; Summer KH
Carcinogenesis; 1988 May; 9(5):811-5. PubMed ID: 3365840
[TBL] [Abstract][Full Text] [Related]
17. Analysis of cytogenetic effect in human lymphocytes induced by metabolically activated 2-nitropropane.
Bauchinger M; Kulka U; Schmid E
Mutat Res; 1987 Mar; 190(3):217-9. PubMed ID: 3821783
[TBL] [Abstract][Full Text] [Related]
18. Analysis of nitrite/nitrate in biological fluids: denitrification of 2-nitropropane in F344 rats.
Sohn OS; Fiala ES
Anal Biochem; 2000 Mar; 279(2):202-8. PubMed ID: 10706789
[TBL] [Abstract][Full Text] [Related]
19. Sulfotransferase-mediated genotoxicity of propane 2-nitronate in cultured ovine seminal vesicle cells.
Kreis P; Degen GH; Andrae U
Mutat Res; 1998 Feb; 413(1):69-81. PubMed ID: 9602860
[TBL] [Abstract][Full Text] [Related]
20. Cytochrome P-450-mediated denitrification of 2-nitropropane in mouse liver microsomes.
Marker EK; Kulkarni AP
J Biochem Toxicol; 1986 Sep; 1(3):71-83. PubMed ID: 3271881
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
