141 related articles for article (PubMed ID: 16391762)
1. Molecular mechanisms of antibiotic resistance: QM/MM modelling of deacylation in a class A beta-lactamase.
Hermann JC; Ridder L; Höltje HD; Mulholland AJ
Org Biomol Chem; 2006 Jan; 4(2):206-10. PubMed ID: 16391762
[TBL] [Abstract][Full Text] [Related]
2. Mechanisms of antibiotic resistance: QM/MM modeling of the acylation reaction of a class A beta-lactamase with benzylpenicillin.
Hermann JC; Hensen C; Ridder L; Mulholland AJ; Höltje HD
J Am Chem Soc; 2005 Mar; 127(12):4454-65. PubMed ID: 15783228
[TBL] [Abstract][Full Text] [Related]
3. Identification of Glu166 as the general base in the acylation reaction of class A beta-lactamases through QM/MM modeling.
Hermann JC; Ridder L; Mulholland AJ; Höltje HD
J Am Chem Soc; 2003 Aug; 125(32):9590-1. PubMed ID: 12904016
[TBL] [Abstract][Full Text] [Related]
4. High level QM/MM modeling of the formation of the tetrahedral intermediate in the acylation of wild type and K73A mutant TEM-1 class A beta-lactamase.
Hermann JC; Pradon J; Harvey JN; Mulholland AJ
J Phys Chem A; 2009 Oct; 113(43):11984-94. PubMed ID: 19791786
[TBL] [Abstract][Full Text] [Related]
5. Ab initio QM/MM study of class A beta-lactamase acylation: dual participation of Glu166 and Lys73 in a concerted base promotion of Ser70.
Meroueh SO; Fisher JF; Schlegel HB; Mobashery S
J Am Chem Soc; 2005 Nov; 127(44):15397-407. PubMed ID: 16262403
[TBL] [Abstract][Full Text] [Related]
6. pKa, MM, and QM studies of mechanisms of beta-lactamases and penicillin-binding proteins: acylation step.
Massova I; Kollman PA
J Comput Chem; 2002 Dec; 23(16):1559-76. PubMed ID: 12395425
[TBL] [Abstract][Full Text] [Related]
7. A theoretical study on the substrate deacylation mechanism of class C beta-lactamase.
Hata M; Tanaka Y; Fujii Y; Neya S; Hoshino T
J Phys Chem B; 2005 Aug; 109(33):16153-60. PubMed ID: 16853052
[TBL] [Abstract][Full Text] [Related]
8. Role of protein flexibility in enzymatic catalysis: quantum mechanical-molecular mechanical study of the deacylation reaction in class A beta-lactamases.
Castillo R; Silla E; Tuñón I
J Am Chem Soc; 2002 Feb; 124(8):1809-16. PubMed ID: 11853460
[TBL] [Abstract][Full Text] [Related]
9. The role of water molecules in the deacylation of acylated structures of class A beta-lactamase.
Ishiguro M; Imajo S
Drug Des Discov; 1999 Aug; 16(2):131-43. PubMed ID: 10533809
[TBL] [Abstract][Full Text] [Related]
10. Mixed quantum mechanical/molecular mechanical (QM/MM) study of the deacylation reaction in a penicillin binding protein (PBP) versus in a class C beta-lactamase.
Gherman BF; Goldberg SD; Cornish VW; Friesner RA
J Am Chem Soc; 2004 Jun; 126(24):7652-64. PubMed ID: 15198613
[TBL] [Abstract][Full Text] [Related]
11. A theoretical study on the activation of Ser70 in the acylation mechanism of cephalosporin antibiotics.
Ke YY; Lin TH
Biophys Chem; 2005 Apr; 114(2-3):103-13. PubMed ID: 15829343
[TBL] [Abstract][Full Text] [Related]
12. Theoretical investigation on reaction of sulbactam with wild-type SHV-1 β-lactamase: acylation, tautomerization, and deacylation.
Li R; Liao JM; Gu CR; Wang YT; Chen CL
J Phys Chem B; 2011 Sep; 115(34):10298-310. PubMed ID: 21797222
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of class D beta-lactamases by diaroyl phosphates.
Majumdar S; Adediran SA; Nukaga M; Pratt RF
Biochemistry; 2005 Dec; 44(49):16121-9. PubMed ID: 16331972
[TBL] [Abstract][Full Text] [Related]
14. Water-assisted reaction mechanism of monozinc beta-lactamases.
Dal Peraro M; Llarrull LI; Rothlisberger U; Vila AJ; Carloni P
J Am Chem Soc; 2004 Oct; 126(39):12661-8. PubMed ID: 15453800
[TBL] [Abstract][Full Text] [Related]
15. 4-Substituted trinems as broad spectrum beta-lactamase inhibitors: structure-based design, synthesis, and biological activity.
Plantan I; Selic L; Mesar T; Anderluh PS; Oblak M; Prezelj A; Hesse L; Andrejasic M; Vilar M; Turk D; Kocijan A; Prevec T; Vilfan G; Kocjan D; Copar A; Urleb U; Solmajer T
J Med Chem; 2007 Aug; 50(17):4113-21. PubMed ID: 17665896
[TBL] [Abstract][Full Text] [Related]
16. Beta-lactamases as fully efficient enzymes. Determination of all the rate constants in the acyl-enzyme mechanism.
Christensen H; Martin MT; Waley SG
Biochem J; 1990 Mar; 266(3):853-61. PubMed ID: 2158301
[TBL] [Abstract][Full Text] [Related]
17. Role of beta-lactam carboxyl group on binding of penicillins and cephalosporins to class C beta-lactamases.
Fenollar-Ferrer C; Frau J; Donoso J; Muñoz F
Proteins; 2003 May; 51(3):442-52. PubMed ID: 12696055
[TBL] [Abstract][Full Text] [Related]
18. [Antibiotic resistance in Escherichia coli O157 isolated between 1998 and 2003 in The Netherlands].
Roest HI; Liebana E; Wannet W; van Duynhoven Y; Veldman KT; Mevius DJ
Tijdschr Diergeneeskd; 2007 Dec; 132(24):954-8. PubMed ID: 18225714
[TBL] [Abstract][Full Text] [Related]
19. Electrostatic analysis of TEM1 beta-lactamase: effect of substrate binding, steep potential gradients and consequences of site-directed mutations.
Swarén P; Maveyraud L; Guillet V; Masson JM; Mourey L; Samama JP
Structure; 1995 Jun; 3(6):603-13. PubMed ID: 8590021
[TBL] [Abstract][Full Text] [Related]
20. The acyl-enzyme mechanism of beta-lactamase action. The evidence for class C Beta-lactamases.
Knott-Hunziker V; Petursson S; Waley SG; Jaurin B; Grundström T
Biochem J; 1982 Nov; 207(2):315-22. PubMed ID: 6818947
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
