These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

260 related articles for article (PubMed ID: 16392798)

  • 1. Synthesis and in vivo validation of [O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)piperazin- 1-yl]butyl}-4-methyl-2H-[1,2,4]triazine-3,5-dione: a novel 5-HT1A receptor agonist positron emission tomography ligand.
    Kumar JS; Majo VJ; Hsiung SC; Millak MS; Liu KP; Tamir H; Prabhakaran J; Simpson NR; Van Heertum RL; Mann JJ; Parsey RV
    J Med Chem; 2006 Jan; 49(1):125-34. PubMed ID: 16392798
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis, in vitro and in vivo evaluation of [O-methyl-11C] 2-{4-[4-(3-methoxyphenyl)piperazin-1-yl]-butyl}-4-methyl-2H-[1,2,4]-triazine-3,5-dione: a novel agonist 5-HT1A receptor PET ligand.
    Prabhakaran J; Parsey RV; Majo VJ; Hsiung SC; Milak MS; Tamir H; Simpson NR; Van Heertum RL; Mann JJ; Dileep Kumar JS
    Bioorg Med Chem Lett; 2006 Apr; 16(8):2101-4. PubMed ID: 16458504
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutant 5-hydroxytryptamine 1A receptor D116A is a receptor activated solely by synthetic ligands with a rich pharmacology.
    Cussac D; Palmier C; Finana F; De Vries L; Tardif S; Léger C; Bernois S; Heusler P
    J Pharmacol Exp Ther; 2009 Oct; 331(1):222-33. PubMed ID: 19605522
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and in vivo evaluation of a novel 5-HT1A receptor agonist radioligand [O-methyl- 11C]2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)dione in nonhuman primates.
    Kumar JS; Prabhakaran J; Majo VJ; Milak MS; Hsiung SC; Tamir H; Simpson NR; Van Heertum RL; Mann JJ; Parsey RV
    Eur J Nucl Med Mol Imaging; 2007 Jul; 34(7):1050-60. PubMed ID: 17221184
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and in vivo evaluation of [11C]SN003 as a PET ligand for CRF1 receptors.
    Kumar JS; Majo VJ; Sullivan GM; Prabhakaran J; Simpson NR; Van Heertum RL; Mann JJ; Parsey RV
    Bioorg Med Chem; 2006 Jun; 14(12):4029-34. PubMed ID: 16529935
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In-vivo effects of the 1,2,4-piperazine derivatives MM5 and MC1, putative 5-HT agonists, on dopamine and serotonin release in rat prefrontal cortex.
    Iskra-Jopa J; Gołembiowska K; Dziubina A; Cybulski M; Duszyńska B; Chilmonczyk Z
    J Pharm Pharmacol; 2005 Feb; 57(2):205-11. PubMed ID: 15720784
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Radiosynthesis and preclinical evaluation of 18F-F13714 as a fluorinated 5-HT1A receptor agonist radioligand for PET neuroimaging.
    Lemoine L; Becker G; Vacher B; Billard T; Lancelot S; Newman-Tancredi A; Zimmer L
    J Nucl Med; 2012 Jun; 53(6):969-76. PubMed ID: 22577236
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lecozotan (SRA-333): a selective serotonin 1A receptor antagonist that enhances the stimulated release of glutamate and acetylcholine in the hippocampus and possesses cognitive-enhancing properties.
    Schechter LE; Smith DL; Rosenzweig-Lipson S; Sukoff SJ; Dawson LA; Marquis K; Jones D; Piesla M; Andree T; Nawoschik S; Harder JA; Womack MD; Buccafusco J; Terry AV; Hoebel B; Rada P; Kelly M; Abou-Gharbia M; Barrett JE; Childers W
    J Pharmacol Exp Ther; 2005 Sep; 314(3):1274-89. PubMed ID: 15951399
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Allosteric modulation of 5-HT(1A) receptors by zinc: Binding studies.
    Barrondo S; Sallés J
    Neuropharmacology; 2009 Feb; 56(2):455-62. PubMed ID: 18951909
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modeling considerations for 11C-CUMI-101, an agonist radiotracer for imaging serotonin 1A receptor in vivo with PET.
    Milak MS; Severance AJ; Ogden RT; Prabhakaran J; Kumar JS; Majo VJ; Mann JJ; Parsey RV
    J Nucl Med; 2008 Apr; 49(4):587-96. PubMed ID: 18344443
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bidirectional modulation of classical fear conditioning in mice by 5-HT(1A) receptor ligands with contrasting intrinsic activities.
    Youn J; Misane I; Eriksson TM; Millan MJ; Ogren SO; Verhage M; Stiedl O
    Neuropharmacology; 2009; 57(5-6):567-76. PubMed ID: 19607850
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, and binding affinities of potential positron emission tomography (PET) ligands for visualization of brain dopamine D3 receptors.
    Leopoldo M; Lacivita E; De Giorgio P; Colabufo NA; Niso M; Berardi F; Perrone R
    J Med Chem; 2006 Jan; 49(1):358-65. PubMed ID: 16392820
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Single exposure to a serotonin 1A receptor agonist, (+)8-hydroxy-2-(di-n-propylamino)-tetralin, produces a prolonged heterologous desensitization of serotonin 2A receptors in neuroendocrine neurons in vivo.
    Carrasco GA; Van de Kar LD; Jia C; Xu H; Chen Z; Chadda R; Garcia F; Muma NA; Battaglia G
    J Pharmacol Exp Ther; 2007 Mar; 320(3):1078-86. PubMed ID: 17159160
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [N-methyl-3H3]AZ10419369 binding to the 5-HT1B receptor: in vitro characterization and in vivo receptor occupancy.
    Maier DL; Sobotka-Briner C; Ding M; Powell ME; Jiang Q; Hill G; Heys JR; Elmore CS; Pierson ME; Mrzljak L
    J Pharmacol Exp Ther; 2009 Jul; 330(1):342-51. PubMed ID: 19401496
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro assessment of the agonist properties of the novel 5-HT1A receptor ligand, CUMI-101 (MMP), in rat brain tissue.
    Hendry N; Christie I; Rabiner EA; Laruelle M; Watson J
    Nucl Med Biol; 2011 Feb; 38(2):273-7. PubMed ID: 21315283
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The counteraction of opioid-induced ventilatory depression by the serotonin 1A-agonist 8-OH-DPAT does not antagonize antinociception in rats in situ and in vivo.
    Guenther U; Manzke T; Wrigge H; Dutschmann M; Zinserling J; Putensen C; Hoeft A
    Anesth Analg; 2009 Apr; 108(4):1169-76. PubMed ID: 19299781
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and in vivo evaluation of [(18)F]2-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione ([(18)F]FECUMI-101) as an imaging probe for 5-HT1A receptor agonist in nonhuman primates.
    Majo VJ; Milak MS; Prabhakaran J; Mali P; Savenkova L; Simpson NR; Mann JJ; Parsey RV; Kumar JS
    Bioorg Med Chem; 2013 Sep; 21(17):5598-604. PubMed ID: 23816046
    [TBL] [Abstract][Full Text] [Related]  

  • 18. N-oxide analogs of WAY-100635: new high affinity 5-HT(1A) receptor antagonists.
    Marchais-Oberwinkler S; Nowicki B; Pike VW; Halldin C; Sandell J; Chou YH; Gulyas B; Brennum LT; Farde L; Wikström HV
    Bioorg Med Chem; 2005 Feb; 13(3):883-93. PubMed ID: 15653354
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and structure-activity relationships of a new model of arylpiperazines. 8. Computational simulation of ligand-receptor interaction of 5-HT(1A)R agonists with selectivity over alpha1-adrenoceptors.
    López-Rodríguez ML; Morcillo MJ; Fernández E; Benhamú B; Tejada I; Ayala D; Viso A; Campillo M; Pardo L; Delgado M; Manzanares J; Fuentes JA
    J Med Chem; 2005 Apr; 48(7):2548-58. PubMed ID: 15801844
    [TBL] [Abstract][Full Text] [Related]  

  • 20. WAY-100635 antagonist-induced plasticity of 5-HT receptors: regulatory differences between a stable cell line and an in vivo native system.
    Khawaja XZ; Smith DL; Nawoschik SP; Zhang J; Dunlop J; Dilks DW; Olsen M; Schechter LE
    J Neurochem; 2006 Jul; 98(1):134-45. PubMed ID: 16805803
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.