331 related articles for article (PubMed ID: 16394198)
1. Probing ligand-specific histamine H1- and H2-receptor conformations with NG-acylated Imidazolylpropylguanidines.
Xie SX; Ghorai P; Ye QZ; Buschauer A; Seifert R
J Pharmacol Exp Ther; 2006 Apr; 317(1):139-46. PubMed ID: 16394198
[TBL] [Abstract][Full Text] [Related]
2. Mutations of Cys-17 and Ala-271 in the human histamine H2 receptor determine the species selectivity of guanidine-type agonists and increase constitutive activity.
Preuss H; Ghorai P; Kraus A; Dove S; Buschauer A; Seifert R
J Pharmacol Exp Ther; 2007 Jun; 321(3):975-82. PubMed ID: 17347323
[TBL] [Abstract][Full Text] [Related]
3. Effects of impromidine- and arpromidine-derived guanidines on recombinant human and guinea pig histamine H1 and H2 receptors.
Xie SX; Schalkhausser F; Ye QZ; Seifert R; Buschauer A
Arch Pharm (Weinheim); 2007 Jan; 340(1):9-16. PubMed ID: 17206612
[TBL] [Abstract][Full Text] [Related]
4. Constitutive activity and ligand selectivity of human, guinea pig, rat, and canine histamine H2 receptors.
Preuss H; Ghorai P; Kraus A; Dove S; Buschauer A; Seifert R
J Pharmacol Exp Ther; 2007 Jun; 321(3):983-95. PubMed ID: 17332265
[TBL] [Abstract][Full Text] [Related]
5. N1-(3-cyclohexylbutanoyl)-N2-[3-(1H-imidazol-4-yl)propyl]guanidine (UR-AK57), a potent partial agonist for the human histamine H1- and H2-receptors.
Xie SX; Kraus A; Ghorai P; Ye QZ; Elz S; Buschauer A; Seifert R
J Pharmacol Exp Ther; 2006 Jun; 317(3):1262-8. PubMed ID: 16554355
[TBL] [Abstract][Full Text] [Related]
6. Molecular basis for the selective interaction of synthetic agonists with the human histamine H1-receptor compared with the guinea pig H1-receptor.
Strasser A; Wittmann HJ; Kunze M; Elz S; Seifert R
Mol Pharmacol; 2009 Mar; 75(3):454-65. PubMed ID: 19047480
[TBL] [Abstract][Full Text] [Related]
7. Pharmacological profile of histaprodifens at four recombinant histamine H1 receptor species isoforms.
Strasser A; Striegl B; Wittmann HJ; Seifert R
J Pharmacol Exp Ther; 2008 Jan; 324(1):60-71. PubMed ID: 17928567
[TBL] [Abstract][Full Text] [Related]
8. Influence of the N-terminus and the E2-loop onto the binding kinetics of the antagonist mepyramine and the partial agonist phenoprodifen to H(1)R.
Wittmann HJ; Seifert R; Strasser A
Biochem Pharmacol; 2011 Dec; 82(12):1910-8. PubMed ID: 21933664
[TBL] [Abstract][Full Text] [Related]
9. Ligand-specific contribution of the N terminus and E2-loop to pharmacological properties of the histamine H1-receptor.
Strasser A; Wittmann HJ; Seifert R
J Pharmacol Exp Ther; 2008 Sep; 326(3):783-91. PubMed ID: 18577700
[TBL] [Abstract][Full Text] [Related]
10. Contribution of binding enthalpy and entropy to affinity of antagonist and agonist binding at human and guinea pig histamine H(1)-receptor.
Wittmann HJ; Seifert R; Strasser A
Mol Pharmacol; 2009 Jul; 76(1):25-37. PubMed ID: 19346300
[TBL] [Abstract][Full Text] [Related]
11. N(G)-acylated aminothiazolylpropylguanidines as potent and selective histamine H(2) receptor agonists.
Kraus A; Ghorai P; Birnkammer T; Schnell D; Elz S; Seifert R; Dove S; Bernhardt G; Buschauer A
ChemMedChem; 2009 Feb; 4(2):232-40. PubMed ID: 19072936
[TBL] [Abstract][Full Text] [Related]
12. Interactions of histamine H1-receptor agonists and antagonists with the human histamine H4-receptor.
Deml KF; Beermann S; Neumann D; Strasser A; Seifert R
Mol Pharmacol; 2009 Nov; 76(5):1019-30. PubMed ID: 19720730
[TBL] [Abstract][Full Text] [Related]
13. Chiral NG-acylated hetarylpropylguanidine-type histamine H2 receptor agonists do not show significant stereoselectivity.
Ghorai P; Kraus A; Birnkammer T; Geyer R; Bernhardt G; Dove S; Seifert R; Elz S; Buschauer A
Bioorg Med Chem Lett; 2010 May; 20(10):3173-6. PubMed ID: 20409707
[TBL] [Abstract][Full Text] [Related]
14. Similar apparent constitutive activity of human histamine H(2)-receptor fused to long and short splice variants of G(salpha).
Wenzel-Seifert K; Kelley MT; Buschauer A; Seifert R
J Pharmacol Exp Ther; 2001 Dec; 299(3):1013-20. PubMed ID: 11714890
[TBL] [Abstract][Full Text] [Related]
15. Point mutations in the second extracellular loop of the histamine H2 receptor do not affect the species-selective activity of guanidine-type agonists.
Preuss H; Ghorai P; Kraus A; Dove S; Buschauer A; Seifert R
Naunyn Schmiedebergs Arch Pharmacol; 2007 Dec; 376(4):253-64. PubMed ID: 17999052
[TBL] [Abstract][Full Text] [Related]
16. N(G)-acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent.
Igel P; Schneider E; Schnell D; Elz S; Seifert R; Buschauer A
J Med Chem; 2009 Apr; 52(8):2623-7. PubMed ID: 19317445
[TBL] [Abstract][Full Text] [Related]
17. Acylguanidines as bioisosteres of guanidines: NG-acylated imidazolylpropylguanidines, a new class of histamine H2 receptor agonists.
Ghorai P; Kraus A; Keller M; Götte C; Igel P; Schneider E; Schnell D; Bernhardt G; Dove S; Zabel M; Elz S; Seifert R; Buschauer A
J Med Chem; 2008 Nov; 51(22):7193-204. PubMed ID: 18950149
[TBL] [Abstract][Full Text] [Related]
18. The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H₂ receptor agonists.
Birnkammer T; Spickenreither A; Brunskole I; Lopuch M; Kagermeier N; Bernhardt G; Dove S; Seifert R; Elz S; Buschauer A
J Med Chem; 2012 Feb; 55(3):1147-60. PubMed ID: 22216892
[TBL] [Abstract][Full Text] [Related]
19. No evidence for functional selectivity of proxyfan at the human histamine H3 receptor coupled to defined Gi/Go protein heterotrimers.
Schnell D; Burleigh K; Trick J; Seifert R
J Pharmacol Exp Ther; 2010 Mar; 332(3):996-1005. PubMed ID: 19959746
[TBL] [Abstract][Full Text] [Related]
20. Structural requirements for inverse agonism and neutral antagonism of indole-, benzimidazole-, and thienopyrrole-derived histamine H4 receptor ligands.
Schneider EH; Strasser A; Thurmond RL; Seifert R
J Pharmacol Exp Ther; 2010 Aug; 334(2):513-21. PubMed ID: 20484153
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
