235 related articles for article (PubMed ID: 16399394)
1. Glutathione S-transferases as regulators of kinase pathways and anticancer drug targets.
Townsend DM; Findlay VL; Tew KD
Methods Enzymol; 2005; 401():287-307. PubMed ID: 16399394
[TBL] [Abstract][Full Text] [Related]
2. A glutathione S-transferase pi-activated prodrug causes kinase activation concurrent with S-glutathionylation of proteins.
Townsend DM; Findlay VJ; Fazilev F; Ogle M; Fraser J; Saavedra JE; Ji X; Keefer LK; Tew KD
Mol Pharmacol; 2006 Feb; 69(2):501-8. PubMed ID: 16288082
[TBL] [Abstract][Full Text] [Related]
3. Tumor cell responses to a novel glutathione S-transferase-activated nitric oxide-releasing prodrug.
Findlay VJ; Townsend DM; Saavedra JE; Buzard GS; Citro ML; Keefer LK; Ji X; Tew KD
Mol Pharmacol; 2004 May; 65(5):1070-9. PubMed ID: 15102935
[TBL] [Abstract][Full Text] [Related]
4. Cellular resistance to a nitric oxide releasing glutathione S-transferase P-activated prodrug, PABA/NO.
Hutchens S; Manevich Y; He L; Tew KD; Townsend DM
Invest New Drugs; 2011 Oct; 29(5):719-29. PubMed ID: 20232108
[TBL] [Abstract][Full Text] [Related]
5. PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity.
Saavedra JE; Srinivasan A; Buzard GS; Davies KM; Waterhouse DJ; Inami K; Wilde TC; Citro ML; Cuellar M; Deschamps JR; Parrish D; Shami PJ; Findlay VJ; Townsend DM; Tew KD; Singh S; Jia L; Ji X; Keefer LK
J Med Chem; 2006 Feb; 49(3):1157-64. PubMed ID: 16451080
[TBL] [Abstract][Full Text] [Related]
6. Redox in redux: Emergent roles for glutathione S-transferase P (GSTP) in regulation of cell signaling and S-glutathionylation.
Tew KD
Biochem Pharmacol; 2007 May; 73(9):1257-69. PubMed ID: 17098212
[TBL] [Abstract][Full Text] [Related]
7. Nitrosative stress-induced s-glutathionylation of protein disulfide isomerase leads to activation of the unfolded protein response.
Townsend DM; Manevich Y; He L; Xiong Y; Bowers RR; Hutchens S; Tew KD
Cancer Res; 2009 Oct; 69(19):7626-34. PubMed ID: 19773442
[TBL] [Abstract][Full Text] [Related]
8. Peptide-bond modified glutathione conjugate analogs modulate GSTpi function in GSH-conjugation, drug sensitivity and JNK signaling.
Burg D; Riepsaame J; Pont C; Mulder G; van de Water B
Biochem Pharmacol; 2006 Jan; 71(3):268-77. PubMed ID: 16337611
[TBL] [Abstract][Full Text] [Related]
9. Synthesis, nitric oxide release, and anti-leukemic activity of glutathione-activated nitric oxide prodrugs: Structural analogues of PABA/NO, an anti-cancer lead compound.
Chakrapani H; Wilde TC; Citro ML; Goodblatt MM; Keefer LK; Saavedra JE
Bioorg Med Chem; 2008 Mar; 16(5):2657-64. PubMed ID: 18060792
[TBL] [Abstract][Full Text] [Related]
10. Novel role for glutathione S-transferase pi. Regulator of protein S-Glutathionylation following oxidative and nitrosative stress.
Townsend DM; Manevich Y; He L; Hutchens S; Pazoles CJ; Tew KD
J Biol Chem; 2009 Jan; 284(1):436-445. PubMed ID: 18990698
[TBL] [Abstract][Full Text] [Related]
11. Glutathione transferases as targets for cancer therapy.
Ruzza P; Rosato A; Rossi CR; Floreani M; Quintieri L
Anticancer Agents Med Chem; 2009 Sep; 9(7):763-77. PubMed ID: 19538171
[TBL] [Abstract][Full Text] [Related]
12. Mild oxidative stress induces S-glutathionylation of STAT3 and enhances chemosensitivity of tumoural cells to chemotherapeutic drugs.
Butturini E; Carcereri de Prati A; Chiavegato G; Rigo A; Cavalieri E; Darra E; Mariotto S
Free Radic Biol Med; 2013 Dec; 65():1322-1330. PubMed ID: 24095958
[TBL] [Abstract][Full Text] [Related]
13. Glutathione transferases and development of new principles to overcome drug resistance.
Sau A; Pellizzari Tregno F; Valentino F; Federici G; Caccuri AM
Arch Biochem Biophys; 2010 Aug; 500(2):116-22. PubMed ID: 20494652
[TBL] [Abstract][Full Text] [Related]
14. Characterization of new potential anticancer drugs designed to overcome glutathione transferase mediated resistance.
Johansson K; Ito M; Schophuizen CM; Mathew Thengumtharayil S; Heuser VD; Zhang J; Shimoji M; Vahter M; Ang WH; Dyson PJ; Shibata A; Shuto S; Ito Y; Abe H; Morgenstern R
Mol Pharm; 2011 Oct; 8(5):1698-708. PubMed ID: 21851097
[TBL] [Abstract][Full Text] [Related]
15. 4-Aryl-1,3,2-oxathiazolylium-5-olate: a novel GST inhibitor to release JNK and activate c-Jun for cancer therapy.
Cui H; Shen J; Lu D; Zhang T; Zhang W; Sun D; Wang PG
Cancer Chemother Pharmacol; 2008 Aug; 62(3):509-15. PubMed ID: 18008069
[TBL] [Abstract][Full Text] [Related]
16. Stabilization of the nitric oxide (NO) prodrugs and anticancer leads, PABA/NO and Double JS-K, through incorporation into PEG-protected nanoparticles.
Kumar V; Hong SY; Maciag AE; Saavedra JE; Adamson DH; Prud'homme RK; Keefer LK; Chakrapani H
Mol Pharm; 2010 Feb; 7(1):291-8. PubMed ID: 20000791
[TBL] [Abstract][Full Text] [Related]
17. Glutathione
Dong SC; Sha HH; Xu XY; Hu TM; Lou R; Li H; Wu JZ; Dan C; Feng J
Drug Des Devel Ther; 2018; 12():3535-3547. PubMed ID: 30425455
[TBL] [Abstract][Full Text] [Related]
18. Synthesis, mechanistic studies, and anti-proliferative activity of glutathione/glutathione S-transferase-activated nitric oxide prodrugs.
Chakrapani H; Kalathur RC; Maciag AE; Citro ML; Ji X; Keefer LK; Saavedra JE
Bioorg Med Chem; 2008 Nov; 16(22):9764-71. PubMed ID: 18930407
[TBL] [Abstract][Full Text] [Related]
19. Structural modifications modulate stability of glutathione-activated arylated diazeniumdiolate prodrugs.
Nandurdikar RS; Maciag AE; Holland RJ; Cao Z; Shami PJ; Anderson LM; Keefer LK; Saavedra JE
Bioorg Med Chem; 2012 May; 20(9):3094-9. PubMed ID: 22480849
[TBL] [Abstract][Full Text] [Related]
20. Cytoprotective and regulatory functions of glutathione S-transferases in cancer cell proliferation and cell death.
Singh S
Cancer Chemother Pharmacol; 2015 Jan; 75(1):1-15. PubMed ID: 25143300
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]