963 related articles for article (PubMed ID: 16399671)
1. Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.
Martin LJ; Pan Y; Price AC; Sterling W; Copeland NG; Jenkins NA; Price DL; Lee MK
J Neurosci; 2006 Jan; 26(1):41-50. PubMed ID: 16399671
[TBL] [Abstract][Full Text] [Related]
2. Transgenic mice with human mutant genes causing Parkinson's disease and amyotrophic lateral sclerosis provide common insight into mechanisms of motor neuron selective vulnerability to degeneration.
Martin LJ
Rev Neurosci; 2007; 18(2):115-36. PubMed ID: 17593875
[TBL] [Abstract][Full Text] [Related]
3. Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice.
Lee MK; Stirling W; Xu Y; Xu X; Qui D; Mandir AS; Dawson TM; Copeland NG; Jenkins NA; Price DL
Proc Natl Acad Sci U S A; 2002 Jun; 99(13):8968-73. PubMed ID: 12084935
[TBL] [Abstract][Full Text] [Related]
4. DNA damage preceding dopamine neuron degeneration in A53T human α-synuclein transgenic mice.
Wang D; Yu T; Liu Y; Yan J; Guo Y; Jing Y; Yang X; Song Y; Tian Y
Biochem Biophys Res Commun; 2016 Dec; 481(1-2):104-110. PubMed ID: 27818201
[TBL] [Abstract][Full Text] [Related]
5. alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease.
Lo Bianco C; Ridet JL; Schneider BL; Deglon N; Aebischer P
Proc Natl Acad Sci U S A; 2002 Aug; 99(16):10813-8. PubMed ID: 12122208
[TBL] [Abstract][Full Text] [Related]
6. A53T-α-synuclein overexpression in murine locus coeruleus induces Parkinson's disease-like pathology in neurons and glia.
Henrich MT; Geibl FF; Lee B; Chiu WH; Koprich JB; Brotchie JM; Timmermann L; Decher N; Matschke LA; Oertel WH
Acta Neuropathol Commun; 2018 May; 6(1):39. PubMed ID: 29747690
[TBL] [Abstract][Full Text] [Related]
7. A53T human α-synuclein overexpression in transgenic mice induces pervasive mitochondria macroautophagy defects preceding dopamine neuron degeneration.
Chen L; Xie Z; Turkson S; Zhuang X
J Neurosci; 2015 Jan; 35(3):890-905. PubMed ID: 25609609
[TBL] [Abstract][Full Text] [Related]
8. Intracerebral Administration of a Ligand-ASO Conjugate Selectively Reduces α-Synuclein Accumulation in Monoamine Neurons of Double Mutant Human A30P*A53T*α-Synuclein Transgenic Mice.
Pavia-Collado R; Cóppola-Segovia V; Miquel-Rio L; Alarcón-Aris D; Rodríguez-Aller R; Torres-López M; Paz V; Ruiz-Bronchal E; Campa L; Artigas F; Montefeltro A; Revilla R; Bortolozzi A
Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33805843
[TBL] [Abstract][Full Text] [Related]
9. Exacerbated synucleinopathy in mice expressing A53T SNCA on a Snca null background.
Cabin DE; Gispert-Sanchez S; Murphy D; Auburger G; Myers RR; Nussbaum RL
Neurobiol Aging; 2005 Jan; 26(1):25-35. PubMed ID: 15585343
[TBL] [Abstract][Full Text] [Related]
10. Changes in Drp1 Function and Mitochondrial Morphology Are Associated with the α-Synuclein Pathology in a Transgenic Mouse Model of Parkinson's Disease.
Portz P; Lee MK
Cells; 2021 Apr; 10(4):. PubMed ID: 33924585
[TBL] [Abstract][Full Text] [Related]
11. Impairment of mitochondria dynamics by human A53T α-synuclein and rescue by NAP (davunetide) in a cell model for Parkinson's disease.
Melo TQ; van Zomeren KC; Ferrari MF; Boddeke HW; Copray JC
Exp Brain Res; 2017 Mar; 235(3):731-742. PubMed ID: 27866262
[TBL] [Abstract][Full Text] [Related]
12. A split-GFP tool reveals differences in the sub-mitochondrial distribution of wt and mutant alpha-synuclein.
Vicario M; Cieri D; Vallese F; Catoni C; Barazzuol L; Berto P; Grinzato A; Barbieri L; Brini M; Calì T
Cell Death Dis; 2019 Nov; 10(11):857. PubMed ID: 31719530
[TBL] [Abstract][Full Text] [Related]
13. Involvement of mortalin/GRP75/mthsp70 in the mitochondrial impairments induced by A53T mutant α-synuclein.
Liu FT; Chen Y; Yang YJ; Yang L; Yu M; Zhao J; Wu JJ; Huang F; Liu W; Ding ZT; Wang J
Brain Res; 2015 Apr; 1604():52-61. PubMed ID: 25665531
[TBL] [Abstract][Full Text] [Related]
14. alpha-Synuclein is colocalized with 14-3-3 and synphilin-1 in A53T transgenic mice.
Shirakashi Y; Kawamoto Y; Tomimoto H; Takahashi R; Ihara M
Acta Neuropathol; 2006 Dec; 112(6):681-9. PubMed ID: 16957925
[TBL] [Abstract][Full Text] [Related]
15. The Parkinson's disease-related protein DJ-1 protects dopaminergic neurons in vivo and cultured cells from alpha-synuclein and 6-hydroxydopamine toxicity.
Batelli S; Invernizzi RW; Negro A; Calcagno E; Rodilossi S; Forloni G; Albani D
Neurodegener Dis; 2015; 15(1):13-23. PubMed ID: 25500798
[TBL] [Abstract][Full Text] [Related]
16. Conditional expression of Parkinson's disease-related mutant α-synuclein in the midbrain dopaminergic neurons causes progressive neurodegeneration and degradation of transcription factor nuclear receptor related 1.
Lin X; Parisiadou L; Sgobio C; Liu G; Yu J; Sun L; Shim H; Gu XL; Luo J; Long CX; Ding J; Mateo Y; Sullivan PH; Wu LG; Goldstein DS; Lovinger D; Cai H
J Neurosci; 2012 Jul; 32(27):9248-64. PubMed ID: 22764233
[TBL] [Abstract][Full Text] [Related]
17. Pesticide exposure exacerbates alpha-synucleinopathy in an A53T transgenic mouse model.
Norris EH; Uryu K; Leight S; Giasson BI; Trojanowski JQ; Lee VM
Am J Pathol; 2007 Feb; 170(2):658-66. PubMed ID: 17255333
[TBL] [Abstract][Full Text] [Related]
18. Rapid Induction of Dopaminergic Neuron Loss Accompanied by Lewy Body-Like Inclusions in A53T BAC-SNCA Transgenic Mice.
Okuda S; Uemura N; Sawamura M; Taguchi T; Ikuno M; Uemura MT; Yamakado H; Takahashi R
Neurotherapeutics; 2022 Jan; 19(1):289-304. PubMed ID: 34935120
[TBL] [Abstract][Full Text] [Related]
19. Astrocytic expression of Parkinson's disease-related A53T alpha-synuclein causes neurodegeneration in mice.
Gu XL; Long CX; Sun L; Xie C; Lin X; Cai H
Mol Brain; 2010 Apr; 3():12. PubMed ID: 20409326
[TBL] [Abstract][Full Text] [Related]
20. Neuropathology in mice expressing human alpha-synuclein.
van der Putten H; Wiederhold KH; Probst A; Barbieri S; Mistl C; Danner S; Kauffmann S; Hofele K; Spooren WP; Ruegg MA; Lin S; Caroni P; Sommer B; Tolnay M; Bilbe G
J Neurosci; 2000 Aug; 20(16):6021-9. PubMed ID: 10934251
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]