BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

424 related articles for article (PubMed ID: 16403413)

  • 1. The co-chaperone p23 arrests the Hsp90 ATPase cycle to trap client proteins.
    McLaughlin SH; Sobott F; Yao ZP; Zhang W; Nielsen PR; Grossmann JG; Laue ED; Robinson CV; Jackson SE
    J Mol Biol; 2006 Feb; 356(3):746-58. PubMed ID: 16403413
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Independent ATPase activity of Hsp90 subunits creates a flexible assembly platform.
    McLaughlin SH; Ventouras LA; Lobbezoo B; Jackson SE
    J Mol Biol; 2004 Nov; 344(3):813-26. PubMed ID: 15533447
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Co-chaperone Sba1 connects the ATPase reaction of Hsp90 to the progression of the chaperone cycle.
    Richter K; Walter S; Buchner J
    J Mol Biol; 2004 Oct; 342(5):1403-13. PubMed ID: 15364569
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural studies on the co-chaperone Hop and its complexes with Hsp90.
    Onuoha SC; Coulstock ET; Grossmann JG; Jackson SE
    J Mol Biol; 2008 Jun; 379(4):732-44. PubMed ID: 18485364
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains.
    Prodromou C; Panaretou B; Chohan S; Siligardi G; O'Brien R; Ladbury JE; Roe SM; Piper PW; Pearl LH
    EMBO J; 2000 Aug; 19(16):4383-92. PubMed ID: 10944121
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biochemical and structural studies of the interaction of Cdc37 with Hsp90.
    Zhang W; Hirshberg M; McLaughlin SH; Lazar GA; Grossmann JG; Nielsen PR; Sobott F; Robinson CV; Jackson SE; Laue ED
    J Mol Biol; 2004 Jul; 340(4):891-907. PubMed ID: 15223329
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Co-chaperone regulation of conformational switching in the Hsp90 ATPase cycle.
    Siligardi G; Hu B; Panaretou B; Piper PW; Pearl LH; Prodromou C
    J Biol Chem; 2004 Dec; 279(50):51989-98. PubMed ID: 15466438
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An unstructured C-terminal region of the Hsp90 co-chaperone p23 is important for its chaperone function.
    Weikl T; Abelmann K; Buchner J
    J Mol Biol; 1999 Oct; 293(3):685-91. PubMed ID: 10543959
    [TBL] [Abstract][Full Text] [Related]  

  • 9. C-terminal regions of Hsp90 are important for trapping the nucleotide during the ATPase cycle.
    Weikl T; Muschler P; Richter K; Veit T; Reinstein J; Buchner J
    J Mol Biol; 2000 Nov; 303(4):583-92. PubMed ID: 11054293
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evidence for chaperone heterocomplexes containing both Hsp90 and VCP.
    Prince T; Shao J; Matts RL; Hartson SD
    Biochem Biophys Res Commun; 2005 Jun; 331(4):1331-7. PubMed ID: 15883021
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stimulation of the weak ATPase activity of human hsp90 by a client protein.
    McLaughlin SH; Smith HW; Jackson SE
    J Mol Biol; 2002 Jan; 315(4):787-98. PubMed ID: 11812147
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Asymmetric activation of the hsp90 dimer by its cochaperone aha1.
    Retzlaff M; Hagn F; Mitschke L; Hessling M; Gugel F; Kessler H; Richter K; Buchner J
    Mol Cell; 2010 Feb; 37(3):344-54. PubMed ID: 20159554
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanistic studies on Hsp90 inhibition by ansamycin derivatives.
    Onuoha SC; Mukund SR; Coulstock ET; Sengerovà B; Shaw J; McLaughlin SH; Jackson SE
    J Mol Biol; 2007 Sep; 372(2):287-97. PubMed ID: 17662999
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co-chaperone p23.
    Young JC; Hartl FU
    EMBO J; 2000 Nov; 19(21):5930-40. PubMed ID: 11060043
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p23 and Aha1: Distinct Functions Promote Client Maturation.
    Biebl MM; Buchner J
    Subcell Biochem; 2023; 101():159-187. PubMed ID: 36520307
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of two p23 co-chaperone isoforms in Leishmania braziliensis exhibiting similar structures and Hsp90 interaction properties despite divergent stabilities.
    Batista FA; Almeida GS; Seraphim TV; Silva KP; Murta SM; Barbosa LR; Borges JC
    FEBS J; 2015 Jan; 282(2):388-406. PubMed ID: 25369258
    [TBL] [Abstract][Full Text] [Related]  

  • 17. High affinity binding of Hsp90 is triggered by multiple discrete segments of its kinase clients.
    Scroggins BT; Prince T; Shao J; Uma S; Huang W; Guo Y; Yun BG; Hedman K; Matts RL; Hartson SD
    Biochemistry; 2003 Nov; 42(43):12550-61. PubMed ID: 14580201
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)-domain co-chaperones.
    Prodromou C; Siligardi G; O'Brien R; Woolfson DN; Regan L; Panaretou B; Ladbury JE; Piper PW; Pearl LH
    EMBO J; 1999 Feb; 18(3):754-62. PubMed ID: 9927435
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Domain-mediated dimerization of the Hsp90 cochaperones Harc and Cdc37.
    Roiniotis J; Masendycz P; Ho S; Scholz GM
    Biochemistry; 2005 May; 44(17):6662-9. PubMed ID: 15850399
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural Analysis of E. coli hsp90 reveals dramatic nucleotide-dependent conformational rearrangements.
    Shiau AK; Harris SF; Southworth DR; Agard DA
    Cell; 2006 Oct; 127(2):329-40. PubMed ID: 17055434
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.