These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 16405869)

  • 1. Binding kinetics and duration of in vivo action of novel prolyl oligopeptidase inhibitors.
    Venäläinen JI; Garcia-Horsman JA; Forsberg MM; Jalkanen A; Wallén EA; Jarho EM; Christiaans JA; Gynther J; Männistö PT
    Biochem Pharmacol; 2006 Feb; 71(5):683-92. PubMed ID: 16405869
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Slow-binding inhibitors of prolyl oligopeptidase with different functional groups at the P1 site.
    Venäläinen JI; Juvonen RO; Garcia-Horsman JA; Wallén EA; Christiaans JA; Jarho EM; Gynther J; Männistö PT
    Biochem J; 2004 Sep; 382(Pt 3):1003-8. PubMed ID: 15217351
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 2(S)-(Cycloalk-1-enecarbonyl)-1-(4-phenyl-butanoyl)pyrrolidines and 2(S)-(aroyl)-1-(4-phenylbutanoyl)pyrrolidines as prolyl oligopeptidase inhibitors.
    Jarho EM; Venäläinen JI; Poutiainen S; Leskinen H; Vepsäläinen J; Christiaans JA; Forsberg MM; Männistö PT; Wallén EA
    Bioorg Med Chem; 2007 Mar; 15(5):2024-31. PubMed ID: 17215128
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New prolyl oligopeptidase inhibitors developed from dicarboxylic acid bis(l-prolyl-pyrrolidine) amides.
    Wallén EA; Christiaans JA; Jarho EM; Forsberg MM; Venäläinen JI; Männistö PT; Gynther J
    J Med Chem; 2003 Oct; 46(21):4543-51. PubMed ID: 14521416
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dicarboxylic acid azacycle l-prolyl-pyrrolidine amides as prolyl oligopeptidase inhibitors and three-dimensional quantitative structure-activity relationship of the enzyme-inhibitor interactions.
    Jarho EM; Wallén EA; Christiaans JA; Forsberg MM; Venäläinen JI; Männistö PT; Gynther J; Poso A
    J Med Chem; 2005 Jul; 48(15):4772-82. PubMed ID: 16033257
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Substrate-dependent, non-hyperbolic kinetics of pig brain prolyl oligopeptidase and its tight binding inhibition by JTP-4819.
    Venäläinen JI; Juvonen RO; Forsberg MM; Garcia-Horsman A; Poso A; Wallen EA; Gynther J; Männistö PT
    Biochem Pharmacol; 2002 Aug; 64(3):463-71. PubMed ID: 12147298
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 4-Phenylbutanoyl-2(S)-acylpyrrolidines and 4-phenylbutanoyl-L-prolyl-2(S)-acylpyrrolidines as prolyl oligopeptidase inhibitors.
    Wallén EA; Christiaans JA; Saario SM; Forsberg MM; Venäläinen JI; Paso HM; Männistö PT; Gynther J
    Bioorg Med Chem; 2002 Jul; 10(7):2199-206. PubMed ID: 11983517
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fluorescence resonance energy transfer (FRET) peptides and cycloretro-inverso peptides derived from bradykinin as substrates and inhibitors of prolyl oligopeptidase.
    Gorrão SS; Hemerly JP; Lima AR; Melo RL; Szeltner Z; Polgár L; Juliano MA; Juliano L
    Peptides; 2007 Nov; 28(11):2146-54. PubMed ID: 17904692
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and characterization of the novel fluorescent prolyl oligopeptidase inhibitor 4-fluoresceinthiocarbamoyl-6-aminocaproyl-L-prolyl-2(S)-(hydroxyacetyl)pyrrolidine.
    Venäläinen JI; Wallén EA; Poso A; García-Horsman JA; Männistö PT
    J Med Chem; 2005 Nov; 48(23):7093-5. PubMed ID: 16279765
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Substrate- and pH-dependent contribution of oxyanion binding site to the catalysis of prolyl oligopeptidase, a paradigm of the serine oligopeptidase family.
    Szeltner Z; Renner V; Polgár L
    Protein Sci; 2000 Feb; 9(2):353-60. PubMed ID: 10716187
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel inhibitors of prolyl endopeptidase: effects of stereochemistry.
    Kolosko N; Bakker AV; Faraci WS; Nagel AA
    Drug Des Discov; 1994 Jan; 11(1):61-71. PubMed ID: 8068820
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prolyl oligopeptidase inhibition by N-acyl-pro-pyrrolidine-type molecules.
    Kánai K; Arányi P; Böcskei Z; Ferenczy G; Harmat V; Simon K; Bátori S; Náray-Szabo G; Hermecz I
    J Med Chem; 2008 Dec; 51(23):7514-22. PubMed ID: 19006380
    [TBL] [Abstract][Full Text] [Related]  

  • 13. cDNA cloning of rat prolyl oligopeptidase and its expression in the ovary during the estrous cycle.
    Kimura A; Takahashi T
    J Exp Zool; 2000 May; 286(6):656-65. PubMed ID: 10766975
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An introduction of a pyridine group into the structure of prolyl oligopeptidase inhibitors.
    Jarho EM; Venäläinen JI; Juntunen J; Yli-Kokko AL; Vepsäläinen J; Christiaans JA; Forsberg MM; Järvinen T; Männistö PT; Wallén EA
    Bioorg Med Chem Lett; 2006 Nov; 16(21):5590-3. PubMed ID: 16919454
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Benzimidazolium salts as small, nonpeptidic and BBB-permeable human prolyl oligopeptidase inhibitors.
    Tarragó T; Masdeu C; Gómez E; Isambert N; Lavilla R; Giralt E
    ChemMedChem; 2008 Oct; 3(10):1558-65. PubMed ID: 18792035
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of diverse psychopharmacological substances on the activity of brain prolyl oligopeptidase.
    Peltonen I; Männistö PT
    Basic Clin Pharmacol Toxicol; 2011 Jan; 108(1):46-54. PubMed ID: 20825390
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Localization of prolyl oligopeptidase in the thalamic and cortical projection neurons: a retrograde neurotracing study in the rat brain.
    Myöhänen TT; Kääriäinen TM; Jalkanen AJ; Piltonen M; Männistö PT
    Neurosci Lett; 2009 Jan; 450(2):201-5. PubMed ID: 19041368
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combination of snap freezing, differential pH two-dimensional reverse-phase high-performance liquid chromatography, and iTRAQ technology for the peptidomic analysis of the effect of prolyl oligopeptidase inhibition in the rat brain.
    Tenorio-Laranga J; Valero ML; Männistö PT; Sánchez del Pino M; García-Horsman JA
    Anal Biochem; 2009 Oct; 393(1):80-7. PubMed ID: 19539595
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A cyclopent-2-enecarbonyl group mimics proline at the P2 position of prolyl oligopeptidase inhibitors.
    Jarho EM; Venäläinen JI; Huuskonen J; Christiaans JA; Garcia-Horsman JA; Forsberg MM; Järvinen T; Gynther J; Männistö PT; Wallén EA
    J Med Chem; 2004 Nov; 47(23):5605-7. PubMed ID: 15509157
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deficient activity of mammalian prolyl oligopeptidase on the immunoactive peptide digestion in coeliac disease.
    Garcia-Horsman JA; Venäläinen JI; Lohi O; Auriola IS; Korponay-Szabo IR; Kaukinen K; Mäki M; Männistö PT
    Scand J Gastroenterol; 2007 May; 42(5):562-71. PubMed ID: 17454876
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.