BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 16408954)

  • 1. Synthesis of a NO-releasing prodrug of rofecoxib.
    Engelhardt FC; Shi YJ; Cowden CJ; Conlon DA; Pipik B; Zhou G; McNamara JM; Dolling UH
    J Org Chem; 2006 Jan; 71(2):480-91. PubMed ID: 16408954
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A general carbometalation, three component coupling strategy for the synthesis of alpha,beta-unsaturated gamma-sultines including thio-rofecoxib, a selective COX-2 inhibitor.
    Smil DV; Souza FE; Fallis AG
    Bioorg Med Chem Lett; 2005 Apr; 15(8):2057-60. PubMed ID: 15808467
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel approach to pro-drugs of lactones: water soluble imidate and ortho-ester derivatives of a furanone-based COX-2 selective inhibitor.
    Poon SF; Stock N; Payne JE; McGuire AR; Stearns B; Yang X; Chen W; Munoz B; Smith ND
    Bioorg Med Chem Lett; 2005 May; 15(9):2259-63. PubMed ID: 15837305
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel (E)-2-(aryl)-3-(4-methanesulfonylphenyl)acrylic ester prodrugs possessing a diazen-1-ium-1,2-diolate moiety: design, synthesis, cyclooxygenase inhibition, and nitric oxide release studies.
    Abdellatif KR; Dong Y; Chen QH; Chowdhury MA; Knaus EE
    Bioorg Med Chem; 2007 Nov; 15(21):6796-801. PubMed ID: 17764958
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rofecoxib analogues possessing a nitric oxide donor sulfohydroxamic acid (SO2NHOH) cyclooxygenase-2 pharmacophore: synthesis, molecular modeling, and biological evaluation as anti-inflammatory agents.
    Bhardwaj A; Huang Z; Kaur J; Knaus EE
    ChemMedChem; 2012 Jan; 7(1):62-7. PubMed ID: 21990143
    [No Abstract]   [Full Text] [Related]  

  • 6. Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its aminosulfonyl analog: Synthesis, biological evaluation and nitric oxide release studies.
    Abdellatif KR; Chowdhury MA; Dong Y; Das D; Yu G; Velázquez C; Suresh MR; Knaus EE
    Bioorg Med Chem; 2009 Jul; 17(14):5182-8. PubMed ID: 19500994
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and biological evaluation of methanesulfonamide analogues of rofecoxib: Replacement of methanesulfonyl by methanesulfonamido decreases cyclooxygenase-2 selectivity.
    Zarghi A; Praveen Rao PN; Knaus EE
    Bioorg Med Chem; 2007 Jan; 15(2):1056-61. PubMed ID: 17067801
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-hydroxymethylphenyl)-1-(4-aminosulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its methanesulfonyl analog: synthesis, biological evaluation and nitric oxide release studies.
    Abdellatif KR; Chowdhury MA; Dong Y; Velázquez C; Das D; Suresh MR; Knaus EE
    Bioorg Med Chem; 2008 Nov; 16(22):9694-8. PubMed ID: 18930406
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A diazen-1-ium-1,2-diolated nitric oxide donor ester prodrug of 3-(4-hydroxymethylphenyl)-4-(4-methanesulfonylphenyl)-5H-furan-2-one: synthesis, biological evaluation and nitric oxide release studies.
    Abdellatif KR; Huang Z; Chowdhury MA; Kaufman S; Knaus EE
    Bioorg Med Chem Lett; 2011 Jul; 21(13):3951-6. PubMed ID: 21641217
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Racemic and chiral sulfoxides as potential prodrugs of the COX-2 inhibitors Vioxx and Arcoxia.
    Caturla F; Amat M; Reinoso RF; Córdoba M; Warrellow G
    Bioorg Med Chem Lett; 2006 Jun; 16(12):3209-12. PubMed ID: 16616494
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A general method for the synthesis of aryl [11C]methylsulfones: potential PET probes for imaging cyclooxygenase-2 expression.
    Majo VJ; Prabhakaran J; Simpson NR; Van Heertum RL; Mann JJ; Kumar JS
    Bioorg Med Chem Lett; 2005 Oct; 15(19):4268-71. PubMed ID: 16054359
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological evaluation of a novel class of rofecoxib analogues as dual inhibitors of cyclooxygenases (COXs) and lipoxygenases (LOXs).
    Chen QH; Rao PN; Knaus EE
    Bioorg Med Chem; 2006 Dec; 14(23):7898-909. PubMed ID: 16904331
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 1-(4-methanesulfonylphenyl)-5-aryl-1H-pyrazol-3-carboxylic acids: synthesis, nitric oxide release studies and anti-inflammatory activities.
    Abdellatif KR; Chowdhury MA; Dong Y; Knaus EE
    Bioorg Med Chem; 2008 Jul; 16(13):6528-34. PubMed ID: 18513975
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design and synthesis of new water-soluble tetrazolide derivatives of celecoxib and rofecoxib as selective cyclooxygenase-2 (COX-2) inhibitors.
    Navidpour L; Amini M; Shafaroodi H; Abdi K; Ghahremani MH; Dehpour AR; Shafiee A
    Bioorg Med Chem Lett; 2006 Sep; 16(17):4483-7. PubMed ID: 16806914
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Water mediated construction of trisubstituted pyrazoles/isoxazoles library using ketene dithioacetals.
    Savant MM; Pansuriya AM; Bhuva CV; Kapuriya N; Patel AS; Audichya VB; Pipaliya PV; Naliapara YT
    J Comb Chem; 2010; 12(1):176-80. PubMed ID: 19950975
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selective synthesis of epolactaene featuring efficient construction of methyl (Z)-2-iodo-2-butenoate and (2R,3S,4S)-2-trimethylsilyl-2,3-epoxy-4-methyl- gamma-butyrolactone.
    Tan Z; Negishi E
    Org Lett; 2006 Jun; 8(13):2783-5. PubMed ID: 16774256
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A prodrug approach to COX-2 inhibitors with methylsulfone.
    Moh JH; Choi YH; Lim KM; Lee KW; Shin SS; Choi JK; Koh HJ; Chung S
    Bioorg Med Chem Lett; 2004 Apr; 14(7):1757-60. PubMed ID: 15026065
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Silenes in organic synthesis: a short synthesis of prelactone B.
    Sellars JD; Steel PG
    Org Biomol Chem; 2006 Sep; 4(17):3223-4. PubMed ID: 17036108
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A Paterno-Büchi approach to the synthesis of merrilactone A.
    Iriondo-Alberdi J; Perea-Buceta JE; Greaney MF
    Org Lett; 2005 Sep; 7(18):3969-71. PubMed ID: 16119944
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Total synthesis of (-)-stemoamide.
    Torssell S; Wanngren E; Somfai P
    J Org Chem; 2007 May; 72(11):4246-9. PubMed ID: 17451274
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.