BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 16414070)

  • 1. The crystal structure of 5'-deoxy-5'-methylthioadenosine phosphorylase II from Sulfolobus solfataricus, a thermophilic enzyme stabilized by intramolecular disulfide bonds.
    Zhang Y; Porcelli M; Cacciapuoti G; Ealick SE
    J Mol Biol; 2006 Mar; 357(1):252-62. PubMed ID: 16414070
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel hyperthermostable 5'-deoxy-5'-methylthioadenosine phosphorylase from the archaeon Sulfolobus solfataricus.
    Cacciapuoti G; Forte S; Moretti MA; Brio A; Zappia V; Porcelli M
    FEBS J; 2005 Apr; 272(8):1886-99. PubMed ID: 15819883
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A corrected space group for Sulfolobus sulfataricus 5'-deoxy-5'-methylthioadenosine phosphorylase II.
    Zhang Y; Zwart PH; Ealick SE
    Acta Crystallogr D Biol Crystallogr; 2012 Mar; 68(Pt 3):249-52. PubMed ID: 22349226
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of disulfide bonds in conformational stability and folding of 5'-deoxy-5'-methylthioadenosine phosphorylase II from the hyperthermophilic archaeon Sulfolobus solfataricus.
    Cacciapuoti G; Fuccio F; Petraccone L; Del Vecchio P; Porcelli M
    Biochim Biophys Acta; 2012 Oct; 1824(10):1136-43. PubMed ID: 22750406
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Purine nucleoside phosphorylases from hyperthermophilic Archaea require a CXC motif for stability and folding.
    Cacciapuoti G; Peluso I; Fuccio F; Porcelli M
    FEBS J; 2009 Oct; 276(20):5799-805. PubMed ID: 19740110
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Multiple disulfide bridges modulate conformational stability and flexibility in hyperthermophilic archaeal purine nucleoside phosphorylase.
    Bagarolo ML; Porcelli M; Martino E; Feller G; Cacciapuoti G
    Biochim Biophys Acta; 2015 Oct; 1854(10 Pt A):1458-65. PubMed ID: 26116147
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Heterologous expression of 5'-methylthioadenosine phosphorylase from the archaeon Sulfolobus solfataricus: characterization of the recombinant protein and involvement of disulfide bonds in thermophilicity and thermostability.
    Cacciapuoti G; Fusco S; Caiazzo N; Zappia V; Porcelli M
    Protein Expr Purif; 1999 Jun; 16(1):125-35. PubMed ID: 10336870
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Efficient Fludarabine-Activating PNP From Archaea as a Guidance for Redesign the Active Site of E. Coli PNP.
    Cacciapuoti G; Bagarolo ML; Martino E; Scafuri B; Marabotti A; Porcelli M
    J Cell Biochem; 2016 May; 117(5):1126-35. PubMed ID: 26477689
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPs.
    Tebbe J; Bzowska A; Wielgus-Kutrowska B; Schröder W; Kazimierczuk Z; Shugar D; Saenger W; Koellner G
    J Mol Biol; 1999 Dec; 294(5):1239-55. PubMed ID: 10600382
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biochemical and structural characterization of mammalian-like purine nucleoside phosphorylase from the Archaeon Pyrococcus furiosus.
    Cacciapuoti G; Gorassini S; Mazzeo MF; Siciliano RA; Carbone V; Zappia V; Porcelli M
    FEBS J; 2007 May; 274(10):2482-95. PubMed ID: 17419725
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: important implications for the mechanism of catalysis.
    Bzowska A; Koellner G; Wielgus-Kutrowska B; Stroh A; Raszewski G; Holý A; Steiner T; Frank J
    J Mol Biol; 2004 Sep; 342(3):1015-32. PubMed ID: 15342253
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus.
    Appleby TC; Mathews II; Porcelli M; Cacciapuoti G; Ealick SE
    J Biol Chem; 2001 Oct; 276(42):39232-42. PubMed ID: 11489901
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structure of purine nucleoside phosphorylase from Thermus thermophilus.
    Tahirov TH; Inagaki E; Ohshima N; Kitao T; Kuroishi C; Ukita Y; Takio K; Kobayashi M; Kuramitsu S; Yokoyama S; Miyano M
    J Mol Biol; 2004 Apr; 337(5):1149-60. PubMed ID: 15046984
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Purification and characterization of extremely thermophilic and thermostable 5'-methylthioadenosine phosphorylase from the archaeon Sulfolobus solfataricus. Purine nucleoside phosphorylase activity and evidence for intersubunit disulfide bonds.
    Cacciapuoti G; Porcelli M; Bertoldo C; De Rosa M; Zappia V
    J Biol Chem; 1994 Oct; 269(40):24762-9. PubMed ID: 7929153
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Calf spleen purine-nucleoside phosphorylase: crystal structure of the binary complex with a potent multisubstrate analogue inhibitor.
    Luić M; Koellner G; Yokomatsu T; Shibuya S; Bzowska A
    Acta Crystallogr D Biol Crystallogr; 2004 Aug; 60(Pt 8):1417-24. PubMed ID: 15272165
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene.
    Dandanell G; Szczepanowski RH; Kierdaszuk B; Shugar D; Bochtler M
    J Mol Biol; 2005 Apr; 348(1):113-25. PubMed ID: 15808857
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structure of the ternary complex of E. coli purine nucleoside phosphorylase with formycin B, a structural analogue of the substrate inosine, and phosphate (Sulphate) at 2.1 A resolution.
    Koellner G; Luić M; Shugar D; Saenger W; Bzowska A
    J Mol Biol; 1998 Jul; 280(1):153-66. PubMed ID: 9653038
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
    Brouns SJ; Barends TR; Worm P; Akerboom J; Turnbull AP; Salmon L; van der Oost J
    J Mol Biol; 2008 May; 379(2):357-71. PubMed ID: 18448118
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase at 1.7 A resolution provides insights into substrate binding and catalysis.
    Appleby TC; Erion MD; Ealick SE
    Structure; 1999 Jun; 7(6):629-41. PubMed ID: 10404592
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pyrimidine-specific ribonucleoside hydrolase from the archaeon Sulfolobus solfataricus--biochemical characterization and homology modeling.
    Porcelli M; Concilio L; Peluso I; Marabotti A; Facchiano A; Cacciapuoti G
    FEBS J; 2008 Apr; 275(8):1900-14. PubMed ID: 18355316
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.