BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 16415351)

  • 21. The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes.
    Edwards KM; Kam CM; Powers JC; Trapani JA
    J Biol Chem; 1999 Oct; 274(43):30468-73. PubMed ID: 10521426
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Cytotoxic T lymphocyte-assisted suicide. Caspase 3 activation is primarily the result of the direct action of granzyme B.
    Atkinson EA; Barry M; Darmon AJ; Shostak I; Turner PC; Moyer RW; Bleackley RC
    J Biol Chem; 1998 Aug; 273(33):21261-6. PubMed ID: 9694885
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Interleukin-1 beta-converting enzyme-like protease cleaves DNA-dependent protein kinase in cytotoxic T cell killing.
    Song Q; Burrows SR; Smith G; Lees-Miller SP; Kumar S; Chan DW; Trapani JA; Alnemri E; Litwack G; Lu H; Moss DJ; Jackson S; Lavin MF
    J Exp Med; 1996 Aug; 184(2):619-26. PubMed ID: 8760815
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells.
    Grossman WJ; Verbsky JW; Tollefsen BL; Kemper C; Atkinson JP; Ley TJ
    Blood; 2004 Nov; 104(9):2840-8. PubMed ID: 15238416
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Activation of an interleukin 1 converting enzyme-dependent apoptosis pathway by granzyme B.
    Shi L; Chen G; MacDonald G; Bergeron L; Li H; Miura M; Rotello RJ; Miller DK; Li P; Seshadri T; Yuan J; Greenberg AH
    Proc Natl Acad Sci U S A; 1996 Oct; 93(20):11002-7. PubMed ID: 8855298
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis.
    Mahoney JA; Odin JA; White SM; Shaffer D; Koff A; Casciola-Rosen L; Rosen A
    Biochem J; 2002 Feb; 361(Pt 3):587-95. PubMed ID: 11802788
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B.
    Afonina IS; Cullen SP; Martin SJ
    Immunol Rev; 2010 May; 235(1):105-16. PubMed ID: 20536558
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Granzymes: a family of lymphocyte granule serine proteases.
    Trapani JA
    Genome Biol; 2001; 2(12):REVIEWS3014. PubMed ID: 11790262
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Identification of the BCL2/adenovirus E1B-19K protein-interacting protein 2 (BNIP-2) as a granzyme B target during human natural killer cell-mediated killing.
    Scott GB; Bowles PA; Wilson EB; Meade JL; Low BC; Davison A; Blair GE; Cook GP
    Biochem J; 2010 Nov; 431(3):423-31. PubMed ID: 20704564
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Nuclear translocation of granzyme B in target cell apoptosis.
    Pinkoski MJ; Heibein JA; Barry M; Bleackley RC
    Cell Death Differ; 2000 Jan; 7(1):17-24. PubMed ID: 10713717
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Granzyme B-induced cell death involves induction of p53 tumor suppressor gene and its activation in tumor target cells.
    Meslin F; Thiery J; Richon C; Jalil A; Chouaib S
    J Biol Chem; 2007 Nov; 282(45):32991-9. PubMed ID: 17855337
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Granzyme B: a natural born killer.
    Lord SJ; Rajotte RV; Korbutt GS; Bleackley RC
    Immunol Rev; 2003 Jun; 193():31-8. PubMed ID: 12752668
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells.
    Shresta S; MacIvor DM; Heusel JW; Russell JH; Ley TJ
    Proc Natl Acad Sci U S A; 1995 Jun; 92(12):5679-83. PubMed ID: 7777569
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Serglycin determines secretory granule repertoire and regulates natural killer cell and cytotoxic T lymphocyte cytotoxicity.
    Sutton VR; Brennan AJ; Ellis S; Danne J; Thia K; Jenkins MR; Voskoboinik I; Pejler G; Johnstone RW; Andrews DM; Trapani JA
    FEBS J; 2016 Mar; 283(5):947-61. PubMed ID: 26756195
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Differential expression of granzyme A and granzyme B proteases and their secretion by fresh rat natural killer cells (NK) and lymphokine-activated killer cells with NK phenotype (LAK-NK).
    Velotti F; Palmieri G; D'Ambrosio D; Piccoli M; Frati L; Santoni A
    Eur J Immunol; 1992 Apr; 22(4):1049-53. PubMed ID: 1551404
    [TBL] [Abstract][Full Text] [Related]  

  • 36. A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes.
    Sun J; Bird CH; Sutton V; McDonald L; Coughlin PB; De Jong TA; Trapani JA; Bird PI
    J Biol Chem; 1996 Nov; 271(44):27802-9. PubMed ID: 8910377
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Characterization of three serine esterases isolated from human IL-2 activated killer cells.
    Hameed A; Lowrey DM; Lichtenheld M; Podack ER
    J Immunol; 1988 Nov; 141(9):3142-7. PubMed ID: 3262682
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The peptide loop consisting of amino acids 139-157 of human granzyme B (fragmentin 2) contains an immunodominant epitope recognized by the mouse.
    Apostolidis VA; Browne KA; Smyth MJ; Trapani JA
    Mol Immunol; 1995 Aug; 32(12):909-17. PubMed ID: 7565817
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Evidence for the existence of granzyme-like serine proteases in teleost cytotoxic cells.
    Praveen K; Evans DL; Jaso-Friedmann L
    J Mol Evol; 2004 Apr; 58(4):449-59. PubMed ID: 15114423
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Granzyme A and B-deficient killer lymphocytes are defective in eliciting DNA fragmentation but retain potent in vivo anti-tumor capacity.
    Davis JE; Smyth MJ; Trapani JA
    Eur J Immunol; 2001 Jan; 31(1):39-47. PubMed ID: 11169436
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.