BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

412 related articles for article (PubMed ID: 16416302)

  • 1. Quantitative prediction of macrolide drug-drug interaction potential from in vitro studies using testosterone as the human cytochrome P4503A substrate.
    Polasek TM; Miners JO
    Eur J Clin Pharmacol; 2006 Mar; 62(3):203-8. PubMed ID: 16416302
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prediction of the in vivo interaction between midazolam and macrolides based on in vitro studies using human liver microsomes.
    Ito K; Ogihara K; Kanamitsu S; Itoh T
    Drug Metab Dispos; 2003 Jul; 31(7):945-54. PubMed ID: 12814973
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin.
    Yamazaki H; Shimada T
    Drug Metab Dispos; 1998 Nov; 26(11):1053-7. PubMed ID: 9806945
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vitro-in vivo extrapolation of zolpidem as a perpetrator of metabolic interactions involving CYP3A.
    Polasek TM; Sadagopal JS; Elliot DJ; Miners JO
    Eur J Clin Pharmacol; 2010 Mar; 66(3):275-83. PubMed ID: 20012430
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prediction of human drug-drug interactions from time-dependent inactivation of CYP3A4 in primary hepatocytes using a population-based simulator.
    Xu L; Chen Y; Pan Y; Skiles GL; Shou M
    Drug Metab Dispos; 2009 Dec; 37(12):2330-9. PubMed ID: 19773538
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prediction of crizotinib-midazolam interaction using the Simcyp population-based simulator: comparison of CYP3A time-dependent inhibition between human liver microsomes versus hepatocytes.
    Mao J; Johnson TR; Shen Z; Yamazaki S
    Drug Metab Dispos; 2013 Feb; 41(2):343-52. PubMed ID: 23129213
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Formation in vitro of an inhibitory cytochrome P450 x Fe2+-metabolite complex with roxithromycin and its decladinosyl, O-dealkyl and N-demethyl metabolites in rat liver microsomes.
    Yamazaki H; Shimada T
    Xenobiotica; 1998 Oct; 28(10):995-1004. PubMed ID: 9849646
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences.
    Greenblatt DJ; von Moltke LL; Harmatz JS; Counihan M; Graf JA; Durol AL; Mertzanis P; Duan SX; Wright CE; Shader RI
    Clin Pharmacol Ther; 1998 Sep; 64(3):278-85. PubMed ID: 9757151
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prediction of in vivo interaction between triazolam and erythromycin based on in vitro studies using human liver microsomes and recombinant human CYP3A4.
    Kanamitsu S; Ito K; Green CE; Tyson CA; Shimada N; Sugiyama Y
    Pharm Res; 2000 Apr; 17(4):419-26. PubMed ID: 10870985
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vivo evaluation of drug-drug interaction via mechanism-based inhibition by macrolide antibiotics in cynomolgus monkeys.
    Ogasawara A; Negishi I; Kozakai K; Kume T
    Drug Metab Dispos; 2009 Nov; 37(11):2127-36. PubMed ID: 19704026
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human cytochrome P-450 3A4: in vitro drug-drug interaction patterns are substrate-dependent.
    Wang RW; Newton DJ; Liu N; Atkins WM; Lu AY
    Drug Metab Dispos; 2000 Mar; 28(3):360-6. PubMed ID: 10681383
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Physiologically based pharmacokinetic model of mechanism-based inhibition of CYP3A by clarithromycin.
    Quinney SK; Zhang X; Lucksiri A; Gorski JC; Li L; Hall SD
    Drug Metab Dispos; 2010 Feb; 38(2):241-8. PubMed ID: 19884323
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prediction of in vivo drug-drug interactions from in vitro data : factors affecting prototypic drug-drug interactions involving CYP2C9, CYP2D6 and CYP3A4.
    Brown HS; Galetin A; Hallifax D; Houston JB
    Clin Pharmacokinet; 2006; 45(10):1035-50. PubMed ID: 16984215
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selection of alternative CYP3A4 probe substrates for clinical drug interaction studies using in vitro data and in vivo simulation.
    Foti RS; Rock DA; Wienkers LC; Wahlstrom JL
    Drug Metab Dispos; 2010 Jun; 38(6):981-7. PubMed ID: 20203109
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential mechanism-based inhibition of CYP3A4 and CYP3A5 by verapamil.
    Wang YH; Jones DR; Hall SD
    Drug Metab Dispos; 2005 May; 33(5):664-71. PubMed ID: 15689501
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selective mechanism-based inactivation of CYP3A4 by CYP3cide (PF-04981517) and its utility as an in vitro tool for delineating the relative roles of CYP3A4 versus CYP3A5 in the metabolism of drugs.
    Walsky RL; Obach RS; Hyland R; Kang P; Zhou S; West M; Geoghegan KF; Helal CJ; Walker GS; Goosen TC; Zientek MA
    Drug Metab Dispos; 2012 Sep; 40(9):1686-97. PubMed ID: 22645092
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of CYP3A-mediated testosterone 6β-hydroxylation by tanshinone IIA and midazolam 1-hydroxylation by cryptotanshinone in human liver microsomes.
    Qiu F; Zhang R; Wang G; Gao C; Sun J; Jiang J; Ma Y
    Xenobiotica; 2010 Dec; 40(12):800-6. PubMed ID: 20964620
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vitro metabolism of midazolam, triazolam, nifedipine, and testosterone by human liver microsomes and recombinant cytochromes p450: role of cyp3a4 and cyp3a5.
    Patki KC; Von Moltke LL; Greenblatt DJ
    Drug Metab Dispos; 2003 Jul; 31(7):938-44. PubMed ID: 12814972
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of CYP3A by erythromycin: in vitro-in vivo correlation in rats.
    Zhang X; Galinsky RE; Kimura RE; Quinney SK; Jones DR; Hall SD
    Drug Metab Dispos; 2010 Jan; 38(1):61-72. PubMed ID: 19797607
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CYP3A5 Contributes significantly to CYP3A-mediated drug oxidations in liver microsomes from Japanese subjects.
    Yamaori S; Yamazaki H; Iwano S; Kiyotani K; Matsumura K; Honda G; Nakagawa K; Ishizaki T; Kamataki T
    Drug Metab Pharmacokinet; 2004 Apr; 19(2):120-9. PubMed ID: 15499178
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.