135 related articles for article (PubMed ID: 16420060)
1. Novel 5alpha-reductase inhibitors: synthesis, structure-activity studies, and pharmacokinetic profile of phenoxybenzoylphenyl acetic acids.
Salem OI; Frotscher M; Scherer C; Neugebauer A; Biemel K; Streiber M; Maas R; Hartmann RW
J Med Chem; 2006 Jan; 49(2):748-59. PubMed ID: 16420060
[TBL] [Abstract][Full Text] [Related]
2. Indole derivatives as a new class of steroid 5 alpha-reductase inhibitors.
Takami H; Koshimura H; Kishibayashi N; Ishii A; Nonaka H; Aoyama S; Kase H; Kumazawa T
J Med Chem; 1996 Dec; 39(26):5047-52. PubMed ID: 8978835
[TBL] [Abstract][Full Text] [Related]
3. Cyclohex-1-ene carboxylic acids: synthesis and biological evaluation of novel inhibitors of human 5 alpha reductase.
Baston E; Salem OI; Hartmann RW
Arch Pharm (Weinheim); 2003 Mar; 336(1):31-8. PubMed ID: 12666251
[TBL] [Abstract][Full Text] [Related]
4. Effects of various pesticides on human 5alpha-reductase activity in prostate and LNCaP cells.
Lo S; King I; Alléra A; Klingmüller D
Toxicol In Vitro; 2007 Apr; 21(3):502-8. PubMed ID: 17218080
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of novel phenylacetic acid derivatives with halogenated benzyl subunit and evaluation as aldose reductase inhibitors.
Rakowitz D; Gmeiner A; Schröder N; Matuszczak B
Eur J Pharm Sci; 2006 Feb; 27(2-3):188-93. PubMed ID: 16260125
[TBL] [Abstract][Full Text] [Related]
6. Pharmacologic basis for the enhanced efficacy of dutasteride against prostatic cancers.
Xu Y; Dalrymple SL; Becker RE; Denmeade SR; Isaacs JT
Clin Cancer Res; 2006 Jul; 12(13):4072-9. PubMed ID: 16818707
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological activity of progesterone derivatives as 5alpha-reductase inhibitors, and their effect on hamster prostate weight.
Bratoeff E; Zambrano A; Heuze I; Palacios A; Ramírez D; Cabeza M
J Enzyme Inhib Med Chem; 2010 Jun; 25(3):306-11. PubMed ID: 19874206
[TBL] [Abstract][Full Text] [Related]
8. 5alpha-reductase inhibitors in benign prostatic hyperplasia and prostate cancer risk reduction.
Rittmaster RS
Best Pract Res Clin Endocrinol Metab; 2008 Apr; 22(2):389-402. PubMed ID: 18471794
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of benzoic acid derivatives as potent, orally active VLA-4 antagonists.
Chiba J; Iimura S; Yoneda Y; Watanabe T; Muro F; Tsubokawa M; Iigou Y; Satoh A; Takayama G; Yokoyama M; Takashi T; Nakayama A; Machinaga N
Bioorg Med Chem; 2007 Feb; 15(4):1679-93. PubMed ID: 17194595
[TBL] [Abstract][Full Text] [Related]
10. Discovery of a novel class of potent coumarin monoamine oxidase B inhibitors: development and biopharmacological profiling of 7-[(3-chlorobenzyl)oxy]-4-[(methylamino)methyl]-2H-chromen-2-one methanesulfonate (NW-1772) as a highly potent, selective, reversible, and orally active monoamine oxidase B inhibitor.
Pisani L; Muncipinto G; Miscioscia TF; Nicolotti O; Leonetti F; Catto M; Caccia C; Salvati P; Soto-Otero R; Mendez-Alvarez E; Passeleu C; Carotti A
J Med Chem; 2009 Nov; 52(21):6685-706. PubMed ID: 19810674
[TBL] [Abstract][Full Text] [Related]
11. Novel steroid 5 alpha-reductase inhibitor FK143: its dual inhibition against the two isozymes and its effect on transcription of the isozyme genes.
Kojo H; Nakayama O; Hirosumi J; Chida N; Notsu Y; Okuhara M
Mol Pharmacol; 1995 Sep; 48(3):401-6. PubMed ID: 7565619
[TBL] [Abstract][Full Text] [Related]
12. C16 and C17 substituted derivatives of pregnenolone and progesterone as inhibitors of 17alpha-hydroxylase-C17, 20-lyase: synthesis and biological evaluation.
Haidar S; Hartmann RW
Arch Pharm (Weinheim); 2002; 335(11-12):526-34. PubMed ID: 12596217
[TBL] [Abstract][Full Text] [Related]
13. Discovery of a novel series of biphenyl benzoic acid derivatives as potent and selective human beta3-adrenergic receptor agonists with good oral bioavailability. Part I.
Imanishi M; Tomishima Y; Itou S; Hamashima H; Nakajima Y; Washizuka K; Sakurai M; Matsui S; Imamura E; Ueshima K; Yamamoto T; Yamamoto N; Ishikawa H; Nakano K; Unami N; Hamada K; Matsumura Y; Takamura F; Hattori K
J Med Chem; 2008 Mar; 51(6):1925-44. PubMed ID: 18307290
[TBL] [Abstract][Full Text] [Related]
14. Evaluation of 4'-substituted bicyclic pyridones as non-steroidal inhibitors of steroid 5alpha-reductase.
McCarthy AR; Hartmann RW; Abell AD
Bioorg Med Chem Lett; 2007 Jul; 17(13):3603-7. PubMed ID: 17490876
[TBL] [Abstract][Full Text] [Related]
15. Discovery of novel aldose reductase inhibitors characterized by an alkoxy-substituted phenylacetic acid core.
Rakowitz D; Gmeiner A; Matuszczak B
Arch Pharm (Weinheim); 2006 Oct; 339(10):559-63. PubMed ID: 17009300
[TBL] [Abstract][Full Text] [Related]
16. [Expression of type I and type II 5alpha-reductase isoenzymes in prostate cancer tissues].
Ye L; Zhang Y; Fang Z
Zhonghua Yi Xue Za Zhi; 2001 Dec; 81(24):1504-7. PubMed ID: 16200776
[TBL] [Abstract][Full Text] [Related]
17. 3,3-diphenylpentane skeleton as a steroid skeleton substitute: novel inhibitors of human 5alpha-reductase 1.
Hosoda S; Hashimoto Y
Bioorg Med Chem Lett; 2007 Oct; 17(19):5414-8. PubMed ID: 17686629
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and activity of 8-substituted benzo[c]quinolizin-3-ones as dual inhibitors of human 5alpha-reductases 1 and 2.
Ferrali A; Menchi G; Occhiato EG; Danza G; Mancina R; Serio M; Guarna A
Bioorg Med Chem Lett; 2005 Jan; 15(1):145-8. PubMed ID: 15582428
[TBL] [Abstract][Full Text] [Related]
19. 5alpha-reductase isozymes and androgen actions in the prostate.
Zhu YS; Imperato-McGinley JL
Ann N Y Acad Sci; 2009 Feb; 1155():43-56. PubMed ID: 19250191
[TBL] [Abstract][Full Text] [Related]
20. Novel C-6 substituted and unsubstituted pregnane derivatives as 5alpha-reductase inhibitors and their effect on hamster flank organs diameter size.
Cabeza M; Zambrano A; Heuze I; Carrizales E; Palacios A; Segura T; Valencia N; Bratoeff E
Steroids; 2009 Oct; 74(10-11):793-802. PubMed ID: 19406144
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]