These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 16421444)

  • 1. Structure of Toxoplasma gondii adenosine kinase in complex with an ATP analog at 1.1 angstroms resolution.
    Zhang Y; El Kouni MH; Ealick SE
    Acta Crystallogr D Biol Crystallogr; 2006 Feb; 62(Pt 2):140-5. PubMed ID: 16421444
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Substrate analogs induce an intermediate conformational change in Toxoplasma gondii adenosine kinase.
    Zhang Y; El Kouni MH; Ealick SE
    Acta Crystallogr D Biol Crystallogr; 2007 Feb; 63(Pt 2):126-34. PubMed ID: 17242506
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
    Schumacher MA; Scott DM; Mathews II; Ealick SE; Roos DS; Ullman B; Brennan RG
    J Mol Biol; 2000 May; 298(5):875-93. PubMed ID: 10801355
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.
    Schumacher MA; Scott DM; Mathews II; Ealick SE; Roos DS; Ullman B; Brennan RG
    J Mol Biol; 2000 Feb; 296(2):549-67. PubMed ID: 10669608
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structures of human adenosine kinase inhibitor complexes reveal two distinct binding modes.
    Muchmore SW; Smith RA; Stewart AO; Cowart MD; Gomtsyan A; Matulenko MA; Yu H; Severin JM; Bhagwat SS; Lee CH; Kowaluk EA; Jarvis MF; Jakob CL
    J Med Chem; 2006 Nov; 49(23):6726-31. PubMed ID: 17154503
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, biological activity and molecular modeling of 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase.
    Yadav V; Chu CK; Rais RH; Al Safarjalani ON; Guarcello V; Naguib FN; el Kouni MH
    J Med Chem; 2004 Apr; 47(8):1987-96. PubMed ID: 15055998
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure of human adenosine kinase at 1.5 A resolution.
    Mathews II; Erion MD; Ealick SE
    Biochemistry; 1998 Nov; 37(45):15607-20. PubMed ID: 9843365
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structure of adenosine kinase from Toxoplasma gondii at 1.8 A resolution.
    Cook WJ; DeLucas LJ; Chattopadhyay D
    Protein Sci; 2000 Apr; 9(4):704-12. PubMed ID: 10794412
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 6-Benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: activities and selective toxicities.
    Rais RH; Al Safarjalani ON; Yadav V; Guarcello V; Kirk M; Chu CK; Naguib FN; el Kouni MH
    Biochem Pharmacol; 2005 May; 69(10):1409-19. PubMed ID: 15857605
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure of Toxoplasma gondii LDH1: active-site differences from human lactate dehydrogenases and the structural basis for efficient APAD+ use.
    Kavanagh KL; Elling RA; Wilson DK
    Biochemistry; 2004 Feb; 43(4):879-89. PubMed ID: 14744130
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural adaptation of an interacting non-native C-terminal helical extension revealed in the crystal structure of NAD+ synthetase from Bacillus anthracis.
    McDonald HM; Pruett PS; Deivanayagam C; Protasevich II; Carson WM; DeLucas LJ; Brouillette WJ; Brouillette CG
    Acta Crystallogr D Biol Crystallogr; 2007 Aug; 63(Pt 8):891-905. PubMed ID: 17642516
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Kinetic mechanism of Toxoplasma gondii adenosine kinase and the highly efficient utilization of adenosine.
    Naguib FN; Rais RH; Al Safarjalani ON; el Kouni MH
    Comp Biochem Physiol B Biochem Mol Biol; 2015 Oct; 188():63-9. PubMed ID: 26112826
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-activity studies on mammalian adenosine kinase.
    Maj MC; Singh B; Gupta RS
    Biochem Biophys Res Commun; 2000 Aug; 275(2):386-93. PubMed ID: 10964675
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of ribokinase by monovalent cations.
    Andersson CE; Mowbray SL
    J Mol Biol; 2002 Jan; 315(3):409-19. PubMed ID: 11786021
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure of the bis(Mg2+)-ATP-oxalate complex of the rabbit muscle pyruvate kinase at 2.1 A resolution: ATP binding over a barrel.
    Larsen TM; Benning MM; Rayment I; Reed GH
    Biochemistry; 1998 May; 37(18):6247-55. PubMed ID: 9572839
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Associative mechanism for phosphoryl transfer: a molecular dynamics simulation of Escherichia coli adenylate kinase complexed with its substrates.
    Krishnamurthy H; Lou H; Kimple A; Vieille C; Cukier RI
    Proteins; 2005 Jan; 58(1):88-100. PubMed ID: 15521058
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Induced fit on sugar binding activates ribokinase.
    Sigrell JA; Cameron AD; Mowbray SL
    J Mol Biol; 1999 Jul; 290(5):1009-18. PubMed ID: 10438599
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nucleotide-induced conformational changes in the Saccharomyces cerevisiae SR protein kinase, Sky1p, revealed by X-ray crystallography.
    Nolen B; Ngo J; Chakrabarti S; Vu D; Adams JA; Ghosh G
    Biochemistry; 2003 Aug; 42(32):9575-85. PubMed ID: 12911299
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structures of an NAD kinase from Archaeoglobus fulgidus in complex with ATP, NAD, or NADP.
    Liu J; Lou Y; Yokota H; Adams PD; Kim R; Kim SH
    J Mol Biol; 2005 Nov; 354(2):289-303. PubMed ID: 16242716
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structures of MEK1 binary and ternary complexes with nucleotides and inhibitors.
    Fischmann TO; Smith CK; Mayhood TW; Myers JE; Reichert P; Mannarino A; Carr D; Zhu H; Wong J; Yang RS; Le HV; Madison VS
    Biochemistry; 2009 Mar; 48(12):2661-74. PubMed ID: 19161339
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.