These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Hydrolysis of N-succinyl-L,L-diaminopimelic acid by the Haemophilus influenzae dapE-encoded desuccinylase: metal activation, solvent isotope effects, and kinetic mechanism. Born TL; Zheng R; Blanchard JS Biochemistry; 1998 Jul; 37(29):10478-87. PubMed ID: 9671518 [TBL] [Abstract][Full Text] [Related]
5. The dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase from Haemophilus influenzae is a dinuclear metallohydrolase. Cosper NJ; Bienvenue DL; Shokes JE; Gilner DM; Tsukamoto T; Scott RA; Holz RC J Am Chem Soc; 2003 Dec; 125(48):14654-5. PubMed ID: 14640610 [TBL] [Abstract][Full Text] [Related]
6. Loss of Catalytic Activity in the E134D, H67A, and H349A Mutants of DapE: Mechanistic Analysis with QM/MM Investigation. Dutta D; Mishra S J Phys Chem B; 2016 Nov; 120(45):11654-11664. PubMed ID: 27783518 [TBL] [Abstract][Full Text] [Related]
7. Structural basis for catalysis by the mono- and dimetalated forms of the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase. Nocek BP; Gillner DM; Fan Y; Holz RC; Joachimiak A J Mol Biol; 2010 Apr; 397(3):617-26. PubMed ID: 20138056 [TBL] [Abstract][Full Text] [Related]
8. Inhibitors of bacterial N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) and demonstration of in vitro antimicrobial activity. Gillner D; Armoush N; Holz RC; Becker DP Bioorg Med Chem Lett; 2009 Nov; 19(22):6350-2. PubMed ID: 19822427 [TBL] [Abstract][Full Text] [Related]
9. Structural Evidence of a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism. Nocek B; Reidl C; Starus A; Heath T; Bienvenue D; Osipiuk J; Jedrzejczak R; Joachimiak A; Becker DP; Holz RC Biochemistry; 2018 Feb; 57(5):574-584. PubMed ID: 29272107 [TBL] [Abstract][Full Text] [Related]
10. Spectroscopic and thermodynamic characterization of the E151D and E151A altered leucine aminopeptidases from Aeromonas proteolytica. Bzymek KP; Swierczek SI; Bennett B; Holz RC Inorg Chem; 2005 Nov; 44(23):8574-80. PubMed ID: 16270998 [TBL] [Abstract][Full Text] [Related]
11. The structural and energetic aspects of substrate binding and the mechanism of action of the DapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) investigated using a hybrid QM/MM method. Dutta D; Mishra S Phys Chem Chem Phys; 2014 Dec; 16(47):26348-58. PubMed ID: 25367594 [TBL] [Abstract][Full Text] [Related]
15. The dimerization domain in DapE enzymes is required for catalysis. Nocek B; Starus A; Makowska-Grzyska M; Gutierrez B; Sanchez S; Jedrzejczak R; Mack JC; Olsen KW; Joachimiak A; Holz RC PLoS One; 2014; 9(5):e93593. PubMed ID: 24806882 [TBL] [Abstract][Full Text] [Related]
16. Identification of a Histidine Metal Ligand in the argE-Encoded N-Acetyl-L-Ornithine Deacetylase from Escherichia coli. McGregor WC; Gillner DM; Swierczek SI; Liu D; Holz RC Springerplus; 2013; 2():482. PubMed ID: 25674394 [TBL] [Abstract][Full Text] [Related]