These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 16425184)

  • 21. The phosphoinositide 3-kinase/Akt pathway regulates cell cycle progression of HL60 human leukemia cells through cytoplasmic relocalization of the cyclin-dependent kinase inhibitor p27(Kip1) and control of cyclin D1 expression.
    Cappellini A; Tabellini G; Zweyer M; Bortul R; Tazzari PL; Billi AM; Falà F; Cocco L; Martelli AM
    Leukemia; 2003 Nov; 17(11):2157-67. PubMed ID: 12931221
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Androgen suppresses proliferation of castration-resistant LNCaP 104-R2 prostate cancer cells through androgen receptor, Skp2, and c-Myc.
    Chuu CP; Kokontis JM; Hiipakka RA; Fukuchi J; Lin HP; Lin CY; Huo C; Su LC; Liao S
    Cancer Sci; 2011 Nov; 102(11):2022-8. PubMed ID: 21781227
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Induction of cell cycle arrest and apoptosis in human prostate carcinoma cells by a recombinant adenovirus expressing p27(Kip1).
    Katner AL; Hoang QB; Gootam P; Jaruga E; Ma Q; Gnarra J; Rayford W
    Prostate; 2002 Sep; 53(1):77-87. PubMed ID: 12210483
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Inhibition of F-Box protein p45(SKP2) expression and stabilization of cyclin-dependent kinase inhibitor p27(KIP1) in vitamin D analog-treated cancer cells.
    Lin R; Wang TT; Miller WH; White JH
    Endocrinology; 2003 Mar; 144(3):749-53. PubMed ID: 12586749
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.
    McCubrey JA; Steelman LS; Abrams SL; Lee JT; Chang F; Bertrand FE; Navolanic PM; Terrian DM; Franklin RA; D'Assoro AB; Salisbury JL; Mazzarino MC; Stivala F; Libra M
    Adv Enzyme Regul; 2006; 46():249-79. PubMed ID: 16854453
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression.
    Graff JR; Konicek BW; McNulty AM; Wang Z; Houck K; Allen S; Paul JD; Hbaiu A; Goode RG; Sandusky GE; Vessella RL; Neubauer BL
    J Biol Chem; 2000 Aug; 275(32):24500-5. PubMed ID: 10827191
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Exogenous p27KIP1 expression induces anti-tumour effects and inhibits the EGFR/PI3K/Akt signalling pathway in PC3 cells.
    Chen J; Xia D; Luo JD; Wang P
    Asian J Androl; 2009 Nov; 11(6):669-77. PubMed ID: 19734935
    [TBL] [Abstract][Full Text] [Related]  

  • 28. ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways.
    Lenferink AE; Busse D; Flanagan WM; Yakes FM; Arteaga CL
    Cancer Res; 2001 Sep; 61(17):6583-91. PubMed ID: 11522658
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Prodigiosin down-regulates SKP2 to induce p27(KIP1) stabilization and antiproliferation in human lung adenocarcinoma cells.
    Hsieh HY; Shieh JJ; Chen CJ; Pan MY; Yang SY; Lin SC; Chang JS; Lee AY; Chang CC
    Br J Pharmacol; 2012 Aug; 166(7):2095-108. PubMed ID: 22372491
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.
    Choi HJ; Chung TW; Kang SK; Lee YC; Ko JH; Kim JG; Kim CH
    Glycobiology; 2006 Jul; 16(7):573-83. PubMed ID: 16574813
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Sulforaphane down-regulates SKP2 to stabilize p27(KIP1) for inducing antiproliferation in human colon adenocarcinoma cells.
    Chung YK; Chi-Hung Or R; Lu CH; Ouyang WT; Yang SY; Chang CC
    J Biosci Bioeng; 2015 Jan; 119(1):35-42. PubMed ID: 25070589
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Vitamin D arrests thyroid carcinoma cell growth and induces p27 dephosphorylation and accumulation through PTEN/akt-dependent and -independent pathways.
    Liu W; Asa SL; Fantus IG; Walfish PG; Ezzat S
    Am J Pathol; 2002 Feb; 160(2):511-9. PubMed ID: 11839571
    [TBL] [Abstract][Full Text] [Related]  

  • 33. CKS1B overexpression implicates clinical aggressiveness of hepatocellular carcinomas but not p27(Kip1) protein turnover: an independent prognosticator with potential p27 (Kip1)-independent oncogenic attributes?
    Huang CW; Lin CY; Huang HY; Liu HW; Chen YJ; Shih DF; Chen HY; Juan CC; Ker CG; Huang CY; Li CF; Shiue YL
    Ann Surg Oncol; 2010 Mar; 17(3):907-22. PubMed ID: 19866239
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Early mitotic inhibitor-1, an anaphase-promoting complex/cyclosome inhibitor, can control tumor cell proliferation in hepatocellular carcinoma: correlation with Skp2 stability and degradation of p27(Kip1).
    Zhao Y; Tang Q; Ni R; Huang X; Wang Y; Lu C; Shen A; Wang Y; Li C; Yuan Q; Chen H; Cheng C; He S
    Hum Pathol; 2013 Mar; 44(3):365-73. PubMed ID: 22995332
    [TBL] [Abstract][Full Text] [Related]  

  • 35. PTEN expression controls cellular response to cetuximab by mediating PI3K/AKT and RAS/RAF/MAPK downstream signaling in KRAS wild-type, hormone refractory prostate cancer cells.
    Bouali S; Chrétien AS; Ramacci C; Rouyer M; Becuwe P; Merlin JL
    Oncol Rep; 2009 Mar; 21(3):731-5. PubMed ID: 19212633
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Elevated Skp2 protein expression in human prostate cancer: association with loss of the cyclin-dependent kinase inhibitor p27 and PTEN and with reduced recurrence-free survival.
    Yang G; Ayala G; De Marzo A; Tian W; Frolov A; Wheeler TM; Thompson TC; Harper JW
    Clin Cancer Res; 2002 Nov; 8(11):3419-26. PubMed ID: 12429629
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Mechanisms in cardiac fibroblast growth: an obligate role for Skp2 and FOXO3a in ERK1/2 MAPK-dependent regulation of p27kip1.
    Pramod S; Shivakumar K
    Am J Physiol Heart Circ Physiol; 2014 Mar; 306(6):H844-55. PubMed ID: 24441545
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Id-1 activates Akt-mediated Wnt signaling and p27(Kip1) phosphorylation through PTEN inhibition.
    Lee JY; Kang MB; Jang SH; Qian T; Kim HJ; Kim CH; Kim Y; Kong G
    Oncogene; 2009 Feb; 28(6):824-31. PubMed ID: 19079342
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells.
    Koga H; Harada M; Ohtsubo M; Shishido S; Kumemura H; Hanada S; Taniguchi E; Yamashita K; Kumashiro R; Ueno T; Sata M
    Hepatology; 2003 May; 37(5):1086-96. PubMed ID: 12717389
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Knockdown of Phospholipase Cε (PLCε) Inhibits Cell Proliferation via Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN)/AKT Signaling Pathway in Human Prostate Cancer.
    Wang X; Fan Y; Du Z; Fan J; Hao Y; Wang J; Wu X; Luo C
    Med Sci Monit; 2018 Jan; 24():254-263. PubMed ID: 29330357
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.