BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 16425184)

  • 21. The phosphoinositide 3-kinase/Akt pathway regulates cell cycle progression of HL60 human leukemia cells through cytoplasmic relocalization of the cyclin-dependent kinase inhibitor p27(Kip1) and control of cyclin D1 expression.
    Cappellini A; Tabellini G; Zweyer M; Bortul R; Tazzari PL; Billi AM; Falà F; Cocco L; Martelli AM
    Leukemia; 2003 Nov; 17(11):2157-67. PubMed ID: 12931221
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Androgen suppresses proliferation of castration-resistant LNCaP 104-R2 prostate cancer cells through androgen receptor, Skp2, and c-Myc.
    Chuu CP; Kokontis JM; Hiipakka RA; Fukuchi J; Lin HP; Lin CY; Huo C; Su LC; Liao S
    Cancer Sci; 2011 Nov; 102(11):2022-8. PubMed ID: 21781227
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Induction of cell cycle arrest and apoptosis in human prostate carcinoma cells by a recombinant adenovirus expressing p27(Kip1).
    Katner AL; Hoang QB; Gootam P; Jaruga E; Ma Q; Gnarra J; Rayford W
    Prostate; 2002 Sep; 53(1):77-87. PubMed ID: 12210483
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Inhibition of F-Box protein p45(SKP2) expression and stabilization of cyclin-dependent kinase inhibitor p27(KIP1) in vitamin D analog-treated cancer cells.
    Lin R; Wang TT; Miller WH; White JH
    Endocrinology; 2003 Mar; 144(3):749-53. PubMed ID: 12586749
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.
    McCubrey JA; Steelman LS; Abrams SL; Lee JT; Chang F; Bertrand FE; Navolanic PM; Terrian DM; Franklin RA; D'Assoro AB; Salisbury JL; Mazzarino MC; Stivala F; Libra M
    Adv Enzyme Regul; 2006; 46():249-79. PubMed ID: 16854453
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression.
    Graff JR; Konicek BW; McNulty AM; Wang Z; Houck K; Allen S; Paul JD; Hbaiu A; Goode RG; Sandusky GE; Vessella RL; Neubauer BL
    J Biol Chem; 2000 Aug; 275(32):24500-5. PubMed ID: 10827191
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Exogenous p27KIP1 expression induces anti-tumour effects and inhibits the EGFR/PI3K/Akt signalling pathway in PC3 cells.
    Chen J; Xia D; Luo JD; Wang P
    Asian J Androl; 2009 Nov; 11(6):669-77. PubMed ID: 19734935
    [TBL] [Abstract][Full Text] [Related]  

  • 28. ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways.
    Lenferink AE; Busse D; Flanagan WM; Yakes FM; Arteaga CL
    Cancer Res; 2001 Sep; 61(17):6583-91. PubMed ID: 11522658
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Prodigiosin down-regulates SKP2 to induce p27(KIP1) stabilization and antiproliferation in human lung adenocarcinoma cells.
    Hsieh HY; Shieh JJ; Chen CJ; Pan MY; Yang SY; Lin SC; Chang JS; Lee AY; Chang CC
    Br J Pharmacol; 2012 Aug; 166(7):2095-108. PubMed ID: 22372491
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.
    Choi HJ; Chung TW; Kang SK; Lee YC; Ko JH; Kim JG; Kim CH
    Glycobiology; 2006 Jul; 16(7):573-83. PubMed ID: 16574813
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Sulforaphane down-regulates SKP2 to stabilize p27(KIP1) for inducing antiproliferation in human colon adenocarcinoma cells.
    Chung YK; Chi-Hung Or R; Lu CH; Ouyang WT; Yang SY; Chang CC
    J Biosci Bioeng; 2015 Jan; 119(1):35-42. PubMed ID: 25070589
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Vitamin D arrests thyroid carcinoma cell growth and induces p27 dephosphorylation and accumulation through PTEN/akt-dependent and -independent pathways.
    Liu W; Asa SL; Fantus IG; Walfish PG; Ezzat S
    Am J Pathol; 2002 Feb; 160(2):511-9. PubMed ID: 11839571
    [TBL] [Abstract][Full Text] [Related]  

  • 33. CKS1B overexpression implicates clinical aggressiveness of hepatocellular carcinomas but not p27(Kip1) protein turnover: an independent prognosticator with potential p27 (Kip1)-independent oncogenic attributes?
    Huang CW; Lin CY; Huang HY; Liu HW; Chen YJ; Shih DF; Chen HY; Juan CC; Ker CG; Huang CY; Li CF; Shiue YL
    Ann Surg Oncol; 2010 Mar; 17(3):907-22. PubMed ID: 19866239
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Early mitotic inhibitor-1, an anaphase-promoting complex/cyclosome inhibitor, can control tumor cell proliferation in hepatocellular carcinoma: correlation with Skp2 stability and degradation of p27(Kip1).
    Zhao Y; Tang Q; Ni R; Huang X; Wang Y; Lu C; Shen A; Wang Y; Li C; Yuan Q; Chen H; Cheng C; He S
    Hum Pathol; 2013 Mar; 44(3):365-73. PubMed ID: 22995332
    [TBL] [Abstract][Full Text] [Related]  

  • 35. PTEN expression controls cellular response to cetuximab by mediating PI3K/AKT and RAS/RAF/MAPK downstream signaling in KRAS wild-type, hormone refractory prostate cancer cells.
    Bouali S; Chrétien AS; Ramacci C; Rouyer M; Becuwe P; Merlin JL
    Oncol Rep; 2009 Mar; 21(3):731-5. PubMed ID: 19212633
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Elevated Skp2 protein expression in human prostate cancer: association with loss of the cyclin-dependent kinase inhibitor p27 and PTEN and with reduced recurrence-free survival.
    Yang G; Ayala G; De Marzo A; Tian W; Frolov A; Wheeler TM; Thompson TC; Harper JW
    Clin Cancer Res; 2002 Nov; 8(11):3419-26. PubMed ID: 12429629
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Mechanisms in cardiac fibroblast growth: an obligate role for Skp2 and FOXO3a in ERK1/2 MAPK-dependent regulation of p27kip1.
    Pramod S; Shivakumar K
    Am J Physiol Heart Circ Physiol; 2014 Mar; 306(6):H844-55. PubMed ID: 24441545
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Id-1 activates Akt-mediated Wnt signaling and p27(Kip1) phosphorylation through PTEN inhibition.
    Lee JY; Kang MB; Jang SH; Qian T; Kim HJ; Kim CH; Kim Y; Kong G
    Oncogene; 2009 Feb; 28(6):824-31. PubMed ID: 19079342
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells.
    Koga H; Harada M; Ohtsubo M; Shishido S; Kumemura H; Hanada S; Taniguchi E; Yamashita K; Kumashiro R; Ueno T; Sata M
    Hepatology; 2003 May; 37(5):1086-96. PubMed ID: 12717389
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Knockdown of Phospholipase Cε (PLCε) Inhibits Cell Proliferation via Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN)/AKT Signaling Pathway in Human Prostate Cancer.
    Wang X; Fan Y; Du Z; Fan J; Hao Y; Wang J; Wu X; Luo C
    Med Sci Monit; 2018 Jan; 24():254-263. PubMed ID: 29330357
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.