BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

110 related articles for article (PubMed ID: 16426077)

  • 1. Evaluating chemical structure similarity as an indicator of cellular growth inhibition.
    Wallqvist A; Huang R; Thanki N; Covell DG
    J Chem Inf Model; 2006; 46(1):430-7. PubMed ID: 16426077
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Assessment of in vitro and in vivo activities in the National Cancer Institute's anticancer screen with respect to chemical structure, target specificity, and mechanism of action.
    Huang R; Wallqvist A; Covell DG
    J Med Chem; 2006 Mar; 49(6):1964-79. PubMed ID: 16539384
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment.
    Mayer SC; Banker AL; Boschelli F; Di L; Johnson M; Kenny CH; Krishnamurthy G; Kutterer K; Moy F; Petusky S; Ravi M; Tkach D; Tsou HR; Xu W
    Bioorg Med Chem Lett; 2008 Jun; 18(12):3641-5. PubMed ID: 18501599
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Integrating high-content screening and ligand-target prediction to identify mechanism of action.
    Young DW; Bender A; Hoyt J; McWhinnie E; Chirn GW; Tao CY; Tallarico JA; Labow M; Jenkins JL; Mitchison TJ; Feng Y
    Nat Chem Biol; 2008 Jan; 4(1):59-68. PubMed ID: 18066055
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of imidazol-2-one derivatives as potential antitumor agents.
    Xue N; Yang X; Wu R; Chen J; He Q; Yang B; Lu X; Hu Y
    Bioorg Med Chem; 2008 Mar; 16(5):2550-7. PubMed ID: 18226907
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In silico chemical library screening and experimental validation of a novel 9-aminoacridine based lead-inhibitor of human S-adenosylmethionine decarboxylase.
    Brooks WH; McCloskey DE; Daniel KG; Ealick SE; Secrist JA; Waud WR; Pegg AE; Guida WC
    J Chem Inf Model; 2007; 47(5):1897-905. PubMed ID: 17676832
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and biological evaluation of 2,5-diaminobenzamide derivatives as anti-proliferating agents.
    Lee SH; Park JW; Hong JE; Park JW; Lee J
    Arch Pharm Res; 2009 Jun; 32(6):803-12. PubMed ID: 19557356
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Predicting antitrichomonal activity: a computational screening using atom-based bilinear indices and experimental proofs.
    Marrero-Ponce Y; Meneses-Marcel A; Castillo-Garit JA; Machado-Tugores Y; Escario JA; Barrio AG; Pereira DM; Nogal-Ruiz JJ; Arán VJ; Martínez-Fernández AR; Torrens F; Rotondo R; Ibarra-Velarde F; Alvarado YJ
    Bioorg Med Chem; 2006 Oct; 14(19):6502-24. PubMed ID: 16875830
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and structure-activity relationships of taxuyunnanine C derivatives as multidrug resistance modulator in MDR cancer cells.
    Hasegawa T; Bai J; Dai J; Bai L; Sakai J; Nishizawa S; Bai Y; Kikuchi M; Abe M; Yamori T; Tomida A; Tsuruo T; Hirose K; Ando M
    Bioorg Med Chem Lett; 2007 Jul; 17(13):3722-8. PubMed ID: 17490878
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NTP toxicology and carcinogenesis studies of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) in female Harlan Sprague-Dawley rats (Gavage Studies).
    National Toxicology Program
    Natl Toxicol Program Tech Rep Ser; 2006 Jan; (520):4-246. PubMed ID: 16628245
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Psoralen analogues: synthesis, inhibitory activity of growth of human tumor cell lines and computational studies.
    Oliveira AM; Raposo MM; Oliveira-Campos AM; Machado AE; Puapairoj P; Pedro M; Nascimento MS; Portela C; Afonso C; Pinto M
    Eur J Med Chem; 2006 Mar; 41(3):367-72. PubMed ID: 16439037
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and characterization of di-phenyl-tin(IV)-salicyliden-ortho-aminophenols: analysis of in vitro antitumor/antioxidant activities and molecular structures.
    Beltrán HI; Damian-Zea C; Hernández-Ortega S; Nieto-Camacho A; Ramírez-Apan MT
    J Inorg Biochem; 2007 Jul; 101(7):1070-85. PubMed ID: 17555822
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antitumor activity of substituted E-3-(3,4,5-trimethoxybenzylidene)-1,3-dihydroindol-2-ones1.
    Andreani A; Burnelli S; Granaiola M; Leoni A; Locatelli A; Morigi R; Rambaldi M; Varoli L; Kunkel MW
    J Med Chem; 2006 Nov; 49(23):6922-4. PubMed ID: 17154522
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
    Romagnoli R; Baraldi PG; Carrion MD; Cara CL; Cruz-Lopez O; Preti D; Tolomeo M; Grimaudo S; Di Cristina A; Zonta N; Balzarini J; Brancale A; Sarkar T; Hamel E
    Bioorg Med Chem; 2008 May; 16(10):5367-76. PubMed ID: 18440234
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure activity relationship of antiproliferative agents using multiple linear regression.
    Winfield LL; Inniss TR; Smith DM
    Chem Biol Drug Des; 2009 Sep; 74(3):309-16. PubMed ID: 19703034
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of tetrahydrotetramethylnaphthalene analogs as adult T-cell leukemia cell-selective proliferation inhibitors in a small chemical library constructed based on multi-template hypothesis.
    Nakamura M; Hamasaki T; Tokitou M; Baba M; Hashimoto Y; Aoyama H
    Bioorg Med Chem; 2009 Jul; 17(13):4740-6. PubMed ID: 19443225
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and structure-activity relationships of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide derivatives as potential agents against A549 lung cancer cells.
    Xia Y; Dong ZW; Zhao BX; Ge X; Meng N; Shin DS; Miao JY
    Bioorg Med Chem; 2007 Nov; 15(22):6893-9. PubMed ID: 17804244
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of compounds with antiproliferative activity as analogues of prenylated natural products existing in Brazilian propolis.
    Pisco L; Kordian M; Peseke K; Feist H; Michalik D; Estrada E; Carvalho J; Hamilton G; Rando D; Quincoces J
    Eur J Med Chem; 2006 Mar; 41(3):401-7. PubMed ID: 16443308
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Probing cell-division phenotype space and Polo-like kinase function using small molecules.
    Peters U; Cherian J; Kim JH; Kwok BH; Kapoor TM
    Nat Chem Biol; 2006 Nov; 2(11):618-26. PubMed ID: 17028580
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Semisynthesis and in vitro anticancer activities of andrographolide analogues.
    Jada SR; Subur GS; Matthews C; Hamzah AS; Lajis NH; Saad MS; Stevens MF; Stanslas J
    Phytochemistry; 2007 Mar; 68(6):904-12. PubMed ID: 17234223
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.