BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 16432160)

  • 1. Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons.
    Yamada HY; Gorbsky GJ
    Mol Cancer Ther; 2006 Jan; 5(1):29-38. PubMed ID: 16432160
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Induction of apoptosis by monastrol, an inhibitor of the mitotic kinesin Eg5, is independent of the spindle checkpoint.
    Chin GM; Herbst R
    Mol Cancer Ther; 2006 Oct; 5(10):2580-91. PubMed ID: 17041103
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human Sug1/p45 is involved in the proteasome-dependent degradation of Sp1.
    Su K; Yang X; Roos MD; Paterson AJ; Kudlow JE
    Biochem J; 2000 Jun; 348 Pt 2(Pt 2):281-9. PubMed ID: 10816420
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mitotic spindle checkpoint inactivation by trichostatin a defines a mechanism for increasing cancer cell killing by microtubule-disrupting agents.
    Dowling M; Voong KR; Kim M; Keutmann MK; Harris E; Kao GD
    Cancer Biol Ther; 2005 Feb; 4(2):197-206. PubMed ID: 15753652
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The docking protein HEF1 is an apoptotic mediator at focal adhesion sites.
    Law SF; O'Neill GM; Fashena SJ; Einarson MB; Golemis EA
    Mol Cell Biol; 2000 Jul; 20(14):5184-95. PubMed ID: 10866674
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Caspase-mediated specific cleavage of BubR1 is a determinant of mitotic progression.
    Kim M; Murphy K; Liu F; Parker SE; Dowling ML; Baff W; Kao GD
    Mol Cell Biol; 2005 Nov; 25(21):9232-48. PubMed ID: 16227576
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The 19S proteasome ATPase Sug1 plays a critical role in regulating MHC class II transcription.
    Bhat KP; Turner JD; Myers SE; Cape AD; Ting JP; Greer SF
    Mol Immunol; 2008 Apr; 45(8):2214-24. PubMed ID: 18215421
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mitotic arrest-associated apoptosis induced by sodium arsenite in A375 melanoma cells is BUBR1-dependent.
    McNeely SC; Taylor BF; States JC
    Toxicol Appl Pharmacol; 2008 Aug; 231(1):61-7. PubMed ID: 18501396
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Low concentrations of taxol cause mitotic delay followed by premature dissociation of p55CDC from Mad2 and BubR1 and abrogation of the spindle checkpoint, leading to aneuploidy.
    Ikui AE; Yang CP; Matsumoto T; Horwitz SB
    Cell Cycle; 2005 Oct; 4(10):1385-8. PubMed ID: 16138009
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Imbalance of the spindle-assembly checkpoint promotes spindle poison-mediated cytotoxicity with distinct kinetics.
    Zeng X; Xu WK; Lok TM; Ma HT; Poon RYC
    Cell Death Dis; 2019 Apr; 10(4):314. PubMed ID: 30952840
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A high throughput, whole cell screen for small molecule inhibitors of the mitotic spindle checkpoint identifies OM137, a novel Aurora kinase inhibitor.
    DeMoe JH; Santaguida S; Daum JR; Musacchio A; Gorbsky GJ
    Cancer Res; 2009 Feb; 69(4):1509-16. PubMed ID: 19190331
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The ubiquitin-proteasome pathway is required for the function of the viral VP16 transcriptional activation domain.
    Zhu Q; Yao J; Wani G; Chen J; Wang QE; Wani AA
    FEBS Lett; 2004 Jan; 556(1-3):19-25. PubMed ID: 14706819
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MCAK is present at centromeres, midspindle and chiasmata and involved in silencing of the spindle assembly checkpoint in mammalian oocytes.
    Vogt E; Sanhaji M; Klein W; Seidel T; Wordeman L; Eichenlaub-Ritter U
    Mol Hum Reprod; 2010 Sep; 16(9):665-84. PubMed ID: 20406800
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The inhibition of Aurora A abrogates the mitotic delay induced by microtubule perturbing agents.
    Wysong DR; Chakravarty A; Hoar K; Ecsedy JA
    Cell Cycle; 2009 Mar; 8(6):876-88. PubMed ID: 19221504
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CDK1 inhibitors antagonize the immediate apoptosis triggered by spindle disruption but promote apoptosis following the subsequent rereplication and abnormal mitosis.
    Chan YW; Ma HT; Wong W; Ho CC; On KF; Poon RY
    Cell Cycle; 2008 May; 7(10):1449-61. PubMed ID: 18418077
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC.
    Chan GK; Jablonski SA; Sudakin V; Hittle JC; Yen TJ
    J Cell Biol; 1999 Sep; 146(5):941-54. PubMed ID: 10477750
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Silencing of the novel p53 target gene Snk/Plk2 leads to mitotic catastrophe in paclitaxel (taxol)-exposed cells.
    Burns TF; Fei P; Scata KA; Dicker DT; El-Deiry WS
    Mol Cell Biol; 2003 Aug; 23(16):5556-71. PubMed ID: 12897130
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p55CDC/hCDC20 mutant induces mitotic catastrophe by inhibiting the MAD2-dependent spindle checkpoint activity in tumor cells.
    Sihn CR; Suh EJ; Lee KH; Kim TY; Kim SH
    Cancer Lett; 2003 Nov; 201(2):203-10. PubMed ID: 14607335
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BubR1 deficiency results in enhanced activation of MEK and ERKs upon microtubule stresses.
    Yang YL; Duan Q; Guo TB; Wang XX; Ruan Q; Xu GT; Zhang JW; Lu ZY; Xu M; Lu L; Dai W
    Cell Prolif; 2007 Jun; 40(3):397-410. PubMed ID: 17531083
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p53 activation in response to mitotic spindle damage requires signaling via BubR1-mediated phosphorylation.
    Ha GH; Baek KH; Kim HS; Jeong SJ; Kim CM; McKeon F; Lee CW
    Cancer Res; 2007 Aug; 67(15):7155-64. PubMed ID: 17671183
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.