139 related articles for article (PubMed ID: 16432163)
1. The sulindac derivatives OSI-461, OSIP486823, and OSIP487703 arrest colon cancer cells in mitosis by causing microtubule depolymerization.
Xiao D; Deguchi A; Gundersen GG; Oehlen B; Arnold L; Weinstein IB
Mol Cancer Ther; 2006 Jan; 5(1):60-7. PubMed ID: 16432163
[TBL] [Abstract][Full Text] [Related]
2. CP248, a derivative of exisulind, causes growth inhibition, mitotic arrest, and abnormalities in microtubule polymerization in glioma cells.
Yoon JT; Palazzo AF; Xiao D; Delohery TM; Warburton PE; Bruce JN; Thompson WJ; Sperl G; Whitehead C; Fetter J; Pamukcu R; Gundersen GG; Weinstein IB
Mol Cancer Ther; 2002 Apr; 1(6):393-404. PubMed ID: 12477052
[TBL] [Abstract][Full Text] [Related]
3. Benzylamide sulindac analogues induce changes in cell shape, loss of microtubules and G(2)-M arrest in a chronic lymphocytic leukemia (CLL) cell line and apoptosis in primary CLL cells.
Moon EY; Lerner A
Cancer Res; 2002 Oct; 62(20):5711-9. PubMed ID: 12384529
[TBL] [Abstract][Full Text] [Related]
4. Induction of apoptosis by the garlic-derived compound S-allylmercaptocysteine (SAMC) is associated with microtubule depolymerization and c-Jun NH(2)-terminal kinase 1 activation.
Xiao D; Pinto JT; Soh JW; Deguchi A; Gundersen GG; Palazzo AF; Yoon JT; Shirin H; Weinstein IB
Cancer Res; 2003 Oct; 63(20):6825-37. PubMed ID: 14583480
[TBL] [Abstract][Full Text] [Related]
5. Activation of protein kinase G up-regulates expression of 15-lipoxygenase-1 in human colon cancer cells.
Deguchi A; Xing SW; Shureiqi I; Yang P; Newman RA; Lippman SM; Feinmark SJ; Oehlen B; Weinstein IB
Cancer Res; 2005 Sep; 65(18):8442-7. PubMed ID: 16166323
[TBL] [Abstract][Full Text] [Related]
6. Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve beta-catenin and cyclin D1 down-regulation.
Li H; Liu L; David ML; Whitehead CM; Chen M; Fetter JR; Sperl GJ; Pamukcu R; Thompson WJ
Biochem Pharmacol; 2002 Nov; 64(9):1325-36. PubMed ID: 12392815
[TBL] [Abstract][Full Text] [Related]
7. Effects of a series of organosulfur compounds on mitotic arrest and induction of apoptosis in colon cancer cells.
Xiao D; Pinto JT; Gundersen GG; Weinstein IB
Mol Cancer Ther; 2005 Sep; 4(9):1388-98. PubMed ID: 16170031
[TBL] [Abstract][Full Text] [Related]
8. Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of c-Jun NH2-terminal kinase 1.
Soh JW; Mao Y; Kim MG; Pamukcu R; Li H; Piazza GA; Thompson WJ; Weinstein IB
Clin Cancer Res; 2000 Oct; 6(10):4136-41. PubMed ID: 11051267
[TBL] [Abstract][Full Text] [Related]
9. Cyclic GMP-dependent protein kinase activation and induction by exisulind and CP461 in colon tumor cells.
Liu L; Li H; Underwood T; Lloyd M; David M; Sperl G; Pamukcu R; Thompson WJ
J Pharmacol Exp Ther; 2001 Nov; 299(2):583-92. PubMed ID: 11602670
[TBL] [Abstract][Full Text] [Related]
10. Arsenic trioxide produces polymerization of microtubules and mitotic arrest before apoptosis in human tumor cell lines.
Ling YH; Jiang JD; Holland JF; Perez-Soler R
Mol Pharmacol; 2002 Sep; 62(3):529-38. PubMed ID: 12181429
[TBL] [Abstract][Full Text] [Related]
11. Sulindac derivatives inhibit growth and induce apoptosis in human prostate cancer cell lines.
Lim JT; Piazza GA; Han EK; Delohery TM; Li H; Finn TS; Buttyan R; Yamamoto H; Sperl GJ; Brendel K; Gross PH; Pamukcu R; Weinstein IB
Biochem Pharmacol; 1999 Oct; 58(7):1097-107. PubMed ID: 10484067
[TBL] [Abstract][Full Text] [Related]
12. 2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules.
Kamath K; Okouneva T; Larson G; Panda D; Wilson L; Jordan MA
Mol Cancer Ther; 2006 Sep; 5(9):2225-33. PubMed ID: 16985056
[TBL] [Abstract][Full Text] [Related]
13. Exisulind and guanylyl cyclase C induce distinct antineoplastic signaling mechanisms in human colon cancer cells.
Pitari GM; Li T; Baksh RI; Waldman SA
Mol Cancer Ther; 2006 May; 5(5):1190-6. PubMed ID: 16731751
[TBL] [Abstract][Full Text] [Related]
14. Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells.
Deguchi A; Thompson WJ; Weinstein IB
Cancer Res; 2004 Jun; 64(11):3966-73. PubMed ID: 15173009
[TBL] [Abstract][Full Text] [Related]
15. Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis.
Piazza GA; Rahm AL; Krutzsch M; Sperl G; Paranka NS; Gross PH; Brendel K; Burt RW; Alberts DS; Pamukcu R
Cancer Res; 1995 Jul; 55(14):3110-6. PubMed ID: 7606732
[TBL] [Abstract][Full Text] [Related]
16. The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth.
Jordan MA; Kamath K; Manna T; Okouneva T; Miller HP; Davis C; Littlefield BA; Wilson L
Mol Cancer Ther; 2005 Jul; 4(7):1086-95. PubMed ID: 16020666
[TBL] [Abstract][Full Text] [Related]
17. Synergistic effects of acyclic retinoid and OSI-461 on growth inhibition and gene expression in human hepatoma cells.
Shimizu M; Suzui M; Deguchi A; Lim JT; Xiao D; Hayes JH; Papadopoulos KP; Weinstein IB
Clin Cancer Res; 2004 Oct; 10(19):6710-21. PubMed ID: 15475462
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of extracellular signal-regulated kinase 1/2 phosphorylation and induction of apoptosis by sulindac metabolites.
Rice PL; Goldberg RJ; Ray EC; Driggers LJ; Ahnen DJ
Cancer Res; 2001 Feb; 61(4):1541-7. PubMed ID: 11245463
[TBL] [Abstract][Full Text] [Related]
19. Exisulind induction of apoptosis involves guanosine 3',5'-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin.
Thompson WJ; Piazza GA; Li H; Liu L; Fetter J; Zhu B; Sperl G; Ahnen D; Pamukcu R
Cancer Res; 2000 Jul; 60(13):3338-42. PubMed ID: 10910034
[TBL] [Abstract][Full Text] [Related]
20. Exisulind: Aptosyn, FGN 1, Prevatac, sulindac sulfone.
Drugs R D; 2004; 5(4):220-6. PubMed ID: 15230629
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]