177 related articles for article (PubMed ID: 16434211)
21. Stable expression of human cytochrome P450 3A4 in conjunction with human NADPH-cytochrome P450 oxidoreductase in V79 Chinese hamster cells.
Schneider A; Schmalix WA; Siruguri V; de Groene EM; Horbach GJ; Kleingeist B; Lang D; Böcker R; Belloc C; Beaune P; Greim H; Doehmer J
Arch Biochem Biophys; 1996 Aug; 332(2):295-304. PubMed ID: 8806738
[TBL] [Abstract][Full Text] [Related]
22. Comparison of CYP3A4 and CYP3A5: the effects of cytochrome b5 and NADPH-cytochrome P450 reductase on testosterone hydroxylation activities.
Lee SJ; Goldstein JA
Drug Metab Pharmacokinet; 2012; 27(6):663-7. PubMed ID: 22785258
[TBL] [Abstract][Full Text] [Related]
23. Genetically engineered modification of P450 monooxygenases: functional analysis of the amino-terminal hydrophobic region and hinge region of the P450/reductase fused enzyme.
Yabusaki Y; Murakami H; Sakaki T; Shibata M; Ohkawa H
DNA; 1988 Dec; 7(10):701-11. PubMed ID: 3148446
[TBL] [Abstract][Full Text] [Related]
24. Coexpression of CPR from various origins enhances biotransformation activity of human CYPs in S. pombe.
Neunzig I; Widjaja M; Peters FT; Maurer HH; Hehn A; Bourgaud F; Bureik M
Appl Biochem Biotechnol; 2013 Aug; 170(7):1751-66. PubMed ID: 23737303
[TBL] [Abstract][Full Text] [Related]
25. Development of Caco-2 cells co-expressing CYP3A4 and NADPH-cytochrome P450 reductase using a human artificial chromosome for the prediction of intestinal extraction ratio of CYP3A4 substrates.
Takenaka T; Kazuki K; Harada N; Kuze J; Chiba M; Iwao T; Matsunaga T; Abe S; Oshimura M; Kazuki Y
Drug Metab Pharmacokinet; 2017 Feb; 32(1):61-68. PubMed ID: 28139373
[TBL] [Abstract][Full Text] [Related]
26. Sensing the Generation of Intracellular Free Electrons Using the Inactive Catalytic Subunit of Cytochrome P450s as a Sink.
Akintade DD; Chaudhuri B
Sensors (Basel); 2020 Jul; 20(14):. PubMed ID: 32708163
[TBL] [Abstract][Full Text] [Related]
27. Xenobiotic metabolism in humanized yeast: engineered yeast cells producing human NADPH-cytochrome P-450 reductase, cytochrome b5, epoxide hydrolase and P-450s.
Urban P; Truan G; Gautier JC; Pompon D
Biochem Soc Trans; 1993 Nov; 21(4):1028-34. PubMed ID: 8131892
[No Abstract] [Full Text] [Related]
28. Progesterone metabolism in recombinant yeast simultaneously expressing bovine cytochromes P450c17 (CYP17A1) and P450c21 (CYP21B1) and yeast NADPH-P450 oxidoreductase.
Sakaki T; Akiyoshi-Shibata M; Yabusaki Y; Manabe K; Murakami H; Ohkawa H
Pharmacogenetics; 1991 Nov; 1(2):86-93. PubMed ID: 1844874
[TBL] [Abstract][Full Text] [Related]
29. Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450.
Campelo D; Esteves F; Brito Palma B; Costa Gomes B; Rueff J; Lautier T; Urban P; Truan G; Kranendonk M
Int J Mol Sci; 2018 Dec; 19(12):. PubMed ID: 30563285
[TBL] [Abstract][Full Text] [Related]
30. The expression of human cytochrome P450IA1 in the yeast Saccharomyces cerevisiae.
Ching MS; Lennard MS; Tucker GT; Woods HF; Kelly DE; Kelly SL
Biochem Pharmacol; 1991 Jul; 42(4):753-8. PubMed ID: 1867632
[TBL] [Abstract][Full Text] [Related]
31. Reconstitution premixes for assays using purified recombinant human cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b5.
Shaw PM; Hosea NA; Thompson DV; Lenius JM; Guengerich FP
Arch Biochem Biophys; 1997 Dec; 348(1):107-15. PubMed ID: 9390180
[TBL] [Abstract][Full Text] [Related]
32. Reconstitution of the enzymatic activities of cytochrome P450s using recombinant flavocytochromes containing rat cytochrome b(5) fused to NADPH--cytochrome P450 reductase with various membrane-binding segments.
Gilep AA; Guryev OL; Usanov SA; Estabrook RW
Arch Biochem Biophys; 2001 Jun; 390(2):215-21. PubMed ID: 11396924
[TBL] [Abstract][Full Text] [Related]
33. Kinetics of testosterone 6beta-hydroxylation in the reconstituted system with similar ratios of purified CYP3A4, NADPH-cytochrome p450 oxidoreductase and cytochrome B5 to human liver microsomes.
Taguchi M; Imaoka S; Yoshii K; Kobayashi K; Hosokawa M; Shimada N; Funae Y; Chiba K
Res Commun Mol Pathol Pharmacol; 2001 Jul; 109(1-2):53-63. PubMed ID: 11458985
[TBL] [Abstract][Full Text] [Related]
34. Hepatic gene expression changes in mouse models with liver-specific deletion or global suppression of the NADPH-cytochrome P450 reductase gene. Mechanistic implications for the regulation of microsomal cytochrome P450 and the fatty liver phenotype.
Weng Y; DiRusso CC; Reilly AA; Black PN; Ding X
J Biol Chem; 2005 Sep; 280(36):31686-98. PubMed ID: 16006652
[TBL] [Abstract][Full Text] [Related]
35. Enhanced in vivo monooxygenase activities of mammalian P450s in engineered yeast cells producing high levels of NADPH-P450 reductase and human cytochrome b5.
Truan G; Cullin C; Reisdorf P; Urban P; Pompon D
Gene; 1993 Mar; 125(1):49-55. PubMed ID: 8449412
[TBL] [Abstract][Full Text] [Related]
36. Progesterone receptor membrane component 1 inhibits the activity of drug-metabolizing cytochromes P450 and binds to cytochrome P450 reductase.
Szczesna-Skorupa E; Kemper B
Mol Pharmacol; 2011 Mar; 79(3):340-50. PubMed ID: 21081644
[TBL] [Abstract][Full Text] [Related]
37. In vitro metabolism of quinidine: the (3S)-3-hydroxylation of quinidine is a specific marker reaction for cytochrome P-4503A4 activity in human liver microsomes.
Nielsen TL; Rasmussen BB; Flinois JP; Beaune P; Brosen K
J Pharmacol Exp Ther; 1999 Apr; 289(1):31-7. PubMed ID: 10086984
[TBL] [Abstract][Full Text] [Related]
38. Mechanism-based inactivation of cytochrome P-450-3A4 by mifepristone (RU486).
He K; Woolf TF; Hollenberg PF
J Pharmacol Exp Ther; 1999 Feb; 288(2):791-7. PubMed ID: 9918590
[TBL] [Abstract][Full Text] [Related]
39. Characterizing cytochrome P450 enzymes involved in plant apocarotenoid metabolism by using an engineered yeast system.
Alagoz Y; Mi J; Balakrishna A; Almarwaey L; Al-Babili S
Methods Enzymol; 2022; 671():527-552. PubMed ID: 35878993
[TBL] [Abstract][Full Text] [Related]
40. Inhibition of human cytochrome P450 3A4 activity by zinc(II) ion.
Kim JS; Yun CH
Toxicol Lett; 2005 Apr; 156(3):341-50. PubMed ID: 15763633
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
