136 related articles for article (PubMed ID: 16434397)
21. An allosteric transition trapped in an intermediate state of a new kinesin-inhibitor complex.
Kaan HY; Ulaganathan V; Hackney DD; Kozielski F
Biochem J; 2009 Dec; 425(1):55-60. PubMed ID: 19793049
[TBL] [Abstract][Full Text] [Related]
22. Application of molecular modeling to analysis of inhibition of kinesin motor proteins of the BimC subfamily by monastrol and related compounds.
Bevan DR; Garst JF; Osborne CK; Sims AM
Chem Biodivers; 2005 Nov; 2(11):1525-32. PubMed ID: 17191952
[TBL] [Abstract][Full Text] [Related]
23. Kinesin has three nucleotide-dependent conformations. Implications for strain-dependent release.
Xing J; Wriggers W; Jefferson GM; Stein R; Cheung HC; Rosenfeld SS
J Biol Chem; 2000 Nov; 275(45):35413-23. PubMed ID: 10852922
[TBL] [Abstract][Full Text] [Related]
24. Inhibition of a mitotic motor protein: where, how, and conformational consequences.
Yan Y; Sardana V; Xu B; Homnick C; Halczenko W; Buser CA; Schaber M; Hartman GD; Huber HE; Kuo LC
J Mol Biol; 2004 Jan; 335(2):547-54. PubMed ID: 14672662
[TBL] [Abstract][Full Text] [Related]
25. Thermodynamics of nucleotide and inhibitor binding to wild-type and ispinesib-resistant forms of human kinesin spindle protein.
Sheth PR; Basso A; Duca JS; Lesburg CA; Ogas P; Gray K; Nale L; Mannarino AF; Prongay AJ; Le HV
Biochemistry; 2009 Nov; 48(46):11045-55. PubMed ID: 19824700
[TBL] [Abstract][Full Text] [Related]
26. Small-molecule and mutational analysis of allosteric Eg5 inhibition by monastrol.
Maliga Z; Mitchison TJ
BMC Chem Biol; 2006 Feb; 6():2. PubMed ID: 16504166
[TBL] [Abstract][Full Text] [Related]
27. Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells.
Müller C; Gross D; Sarli V; Gartner M; Giannis A; Bernhardt G; Buschauer A
Cancer Chemother Pharmacol; 2007 Feb; 59(2):157-64. PubMed ID: 16703323
[TBL] [Abstract][Full Text] [Related]
28. Induction of apoptosis by monastrol, an inhibitor of the mitotic kinesin Eg5, is independent of the spindle checkpoint.
Chin GM; Herbst R
Mol Cancer Ther; 2006 Oct; 5(10):2580-91. PubMed ID: 17041103
[TBL] [Abstract][Full Text] [Related]
29. Bioisosteric approach in designing new monastrol derivatives: an investigation on their ADMET prediction using in silico derived parameters.
Hassan SF; Rashid U; Ansari FL; Ul-Haq Z
J Mol Graph Model; 2013 Sep; 45():202-10. PubMed ID: 24080467
[TBL] [Abstract][Full Text] [Related]
30. The conserved L5 loop establishes the pre-powerstroke conformation of the Kinesin-5 motor, eg5.
Larson AG; Naber N; Cooke R; Pate E; Rice SE
Biophys J; 2010 Jun; 98(11):2619-27. PubMed ID: 20513406
[TBL] [Abstract][Full Text] [Related]
31. Interaction of the mitotic kinesin Eg5 inhibitor monastrol with P-glycoprotein.
Peters T; Lindenmaier H; Haefeli WE; Weiss J
Naunyn Schmiedebergs Arch Pharmacol; 2006 Jan; 372(4):291-9. PubMed ID: 16365780
[TBL] [Abstract][Full Text] [Related]
32. Mechanistic analysis of the mitotic kinesin Eg5.
Cochran JC; Sontag CA; Maliga Z; Kapoor TM; Correia JJ; Gilbert SP
J Biol Chem; 2004 Sep; 279(37):38861-70. PubMed ID: 15247293
[TBL] [Abstract][Full Text] [Related]
33. The effect of monastrol on the processive motility of a dimeric kinesin-5 head/kinesin-1 stalk chimera.
Lakämper S; Thiede C; Düselder A; Reiter S; Korneev MJ; Kapitein LC; Peterman EJ; Schmidt CF
J Mol Biol; 2010 May; 399(1):1-8. PubMed ID: 20227420
[TBL] [Abstract][Full Text] [Related]
34. Analysis of the interaction of the Eg5 Loop5 with the nucleotide site.
Harrington TD; Naber N; Larson AG; Cooke R; Rice SE; Pate E
J Theor Biol; 2011 Nov; 289():107-15. PubMed ID: 21872609
[TBL] [Abstract][Full Text] [Related]
35. New chemical tools for investigating human mitotic kinesin Eg5.
Klein E; DeBonis S; Thiede B; Skoufias DA; Kozielski F; Lebeau L
Bioorg Med Chem; 2007 Oct; 15(19):6474-88. PubMed ID: 17587586
[TBL] [Abstract][Full Text] [Related]
36. Centrin: another target of monastrol, an inhibitor of mitotic spindle.
Duan L; Wang TQ; Bian W; Liu W; Sun Y; Yang BS
Spectrochim Acta A Mol Biomol Spectrosc; 2015 Feb; 137():1086-91. PubMed ID: 25300040
[TBL] [Abstract][Full Text] [Related]
37. Photocontrol of mitotic kinesin Eg5 facilitated by thiol-reactive photochromic molecules incorporated into the loop L5 functional loop.
Ishikawa K; Tamura Y; Maruta S
J Biochem; 2014 Mar; 155(3):195-206. PubMed ID: 24334276
[TBL] [Abstract][Full Text] [Related]
38. Biochemical and Biophysical characterization of curcumin binding to human mitotic kinesin Eg5: Insights into the inhibitory mechanism of curcumin on Eg5.
Raghav D; Sebastian J; Rathinasamy K
Int J Biol Macromol; 2018 Apr; 109():1189-1208. PubMed ID: 29162464
[TBL] [Abstract][Full Text] [Related]
39. The loop 5 element structurally and kinetically coordinates dimers of the human kinesin-5, Eg5.
Waitzman JS; Larson AG; Cochran JC; Naber N; Cooke R; Jon Kull F; Pate E; Rice SE
Biophys J; 2011 Dec; 101(11):2760-9. PubMed ID: 22261065
[TBL] [Abstract][Full Text] [Related]
40. Transient exposure to the Eg5 kinesin inhibitor monastrol leads to syntelic orientation of chromosomes and aneuploidy in mouse oocytes.
Mailhes JB; Mastromatteo C; Fuseler JW
Mutat Res; 2004 Apr; 559(1-2):153-67. PubMed ID: 15066583
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]