These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

98 related articles for article (PubMed ID: 16434397)

  • 61. The role of Kinesin neck linker and neck in velocity regulation.
    Kalchishkova N; Böhm KJ
    J Mol Biol; 2008 Sep; 382(1):127-35. PubMed ID: 18640125
    [TBL] [Abstract][Full Text] [Related]  

  • 62. Identification of novel scaffolds to inhibit human mitotic kinesin Eg5 targeting the second allosteric binding site using in silico methods.
    Makala H; Ulaganathan V
    J Recept Signal Transduct Res; 2018 Feb; 38(1):12-19. PubMed ID: 29041840
    [TBL] [Abstract][Full Text] [Related]  

  • 63. Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen.
    Mayer TU; Kapoor TM; Haggarty SJ; King RW; Schreiber SL; Mitchison TJ
    Science; 1999 Oct; 286(5441):971-4. PubMed ID: 10542155
    [TBL] [Abstract][Full Text] [Related]  

  • 64. Allosteric drug discrimination is coupled to mechanochemical changes in the kinesin-5 motor core.
    Kim ED; Buckley R; Learman S; Richard J; Parke C; Worthylake DK; Wojcik EJ; Walker RA; Kim S
    J Biol Chem; 2010 Jun; 285(24):18650-61. PubMed ID: 20299460
    [TBL] [Abstract][Full Text] [Related]  

  • 65. A posttranslational modification of the mitotic kinesin Eg5 that enhances its mechanochemical coupling and alters its mitotic function.
    Muretta JM; Reddy BJN; Scarabelli G; Thompson AF; Jariwala S; Major J; Venere M; Rich JN; Willard B; Thomas DD; Stumpff J; Grant BJ; Gross SP; Rosenfeld SS
    Proc Natl Acad Sci U S A; 2018 Feb; 115(8):E1779-E1788. PubMed ID: 29432173
    [TBL] [Abstract][Full Text] [Related]  

  • 66. Rapid preparation of the mitotic kinesin Eg5 inhibitor monastrol using controlled microwave-assisted synthesis.
    Dallinger D; Kappe CO
    Nat Protoc; 2007; 2(2):317-21. PubMed ID: 17406591
    [TBL] [Abstract][Full Text] [Related]  

  • 67. Comparison of the Effects of Monastrol and Oxomonastrol on Human Hepatoma Cell Line HepG2/C3A.
    Marques LA; Semprebon SC; Sartori D; DE Fátima Â; Ribeiro LR; Mantovani MS
    Anticancer Res; 2017 Mar; 37(3):1197-1204. PubMed ID: 28314282
    [TBL] [Abstract][Full Text] [Related]  

  • 68. Development of high-throughput screens for discovery of kinesin adenosine triphosphatase modulators.
    Funk CJ; Davis AS; Hopkins JA; Middleton KM
    Anal Biochem; 2004 Jun; 329(1):68-76. PubMed ID: 15136168
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Antiproliferative activity of monastrol in human adenocarcinoma (MCF-7) and non-tumor (HB4a) breast cells.
    Marques LA; Semprebon SC; Niwa AM; D'Epiro GF; Sartori D; de Fátima Â; Ribeiro LR; Mantovani MS
    Naunyn Schmiedebergs Arch Pharmacol; 2016 Dec; 389(12):1279-1288. PubMed ID: 27592117
    [TBL] [Abstract][Full Text] [Related]  

  • 70. Kinesin-5 motors are required for organization of spindle microtubules in Silvetia compressa zygotes.
    Peters NT; Kropf DL
    BMC Plant Biol; 2006 Aug; 6():19. PubMed ID: 16945151
    [TBL] [Abstract][Full Text] [Related]  

  • 71. Structural rearrangements in the active site of smooth-muscle myosin.
    Robertson CI; Gaffney DP; Chrin LR; Berger CL
    Biophys J; 2005 Sep; 89(3):1882-92. PubMed ID: 15951390
    [TBL] [Abstract][Full Text] [Related]  

  • 72. Eg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrix.
    Kapoor TM; Mitchison TJ
    J Cell Biol; 2001 Sep; 154(6):1125-33. PubMed ID: 11564753
    [TBL] [Abstract][Full Text] [Related]  

  • 73. Removal of tightly bound ADP induces distinct structural changes of the two tryptophan-containing regions of the ncd motor domain.
    Morii H; Shimizu T; Mizuno N; Edamatsu M; Ogawa K; Shimizu Y; Toyoshima YY
    J Biochem; 2005 Jul; 138(1):95-104. PubMed ID: 16046453
    [TBL] [Abstract][Full Text] [Related]  

  • 74. Novel Allosteric Pathway of Eg5 Regulation Identified through Multivariate Statistical Analysis of Hydrogen-Exchange Mass Spectrometry (HX-MS) Ligand Screening Data.
    Sheff JG; Farshidfar F; Bathe OF; Kopciuk K; Gentile F; Tuszynski J; Barakat K; Schriemer DC
    Mol Cell Proteomics; 2017 Mar; 16(3):428-437. PubMed ID: 28062800
    [TBL] [Abstract][Full Text] [Related]  

  • 75. Helix capping interactions stabilize the N-terminus of the kinesin neck coiled-coil.
    Tripet B; Hodges RS
    J Struct Biol; 2002; 137(1-2):220-35. PubMed ID: 12064948
    [TBL] [Abstract][Full Text] [Related]  

  • 76. The role of microtubules in processive kinesin movement.
    Kikkawa M
    Trends Cell Biol; 2008 Mar; 18(3):128-35. PubMed ID: 18280159
    [TBL] [Abstract][Full Text] [Related]  

  • 77. Dimeric Eg5 maintains processivity through alternating-site catalysis with rate-limiting ATP hydrolysis.
    Krzysiak TC; Gilbert SP
    J Biol Chem; 2006 Dec; 281(51):39444-54. PubMed ID: 17062577
    [TBL] [Abstract][Full Text] [Related]  

  • 78. Identification of MAC1: A Small Molecule That Rescues Spindle Bipolarity in Monastrol-Treated Cells.
    Al-Obaidi N; Mitchison TJ; Crews CM; Mayer TU
    ACS Chem Biol; 2016 Jun; 11(6):1544-51. PubMed ID: 27121275
    [TBL] [Abstract][Full Text] [Related]  

  • 79. Structure-activity relationship of S-trityl-L-cysteine analogues as inhibitors of the human mitotic kinesin Eg5.
    Debonis S; Skoufias DA; Indorato RL; Liger F; Marquet B; Laggner C; Joseph B; Kozielski F
    J Med Chem; 2008 Mar; 51(5):1115-25. PubMed ID: 18266314
    [TBL] [Abstract][Full Text] [Related]  

  • 80. Two conformations in the human kinesin power stroke defined by X-ray crystallography and EPR spectroscopy.
    Sindelar CV; Budny MJ; Rice S; Naber N; Fletterick R; Cooke R
    Nat Struct Biol; 2002 Nov; 9(11):844-8. PubMed ID: 12368902
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.