These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 16436456)

  • 1. Differential expression of novel naturally occurring splice variants of PTEN and their functional consequences in Cowden syndrome and sporadic breast cancer.
    Agrawal S; Eng C
    Hum Mol Genet; 2006 Mar; 15(5):777-87. PubMed ID: 16436456
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Distinct expression profiles for PTEN transcript and its splice variants in Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome.
    Sarquis MS; Agrawal S; Shen L; Pilarski R; Zhou XP; Eng C
    Am J Hum Genet; 2006 Jul; 79(1):23-30. PubMed ID: 16773562
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Germline PTEN promoter mutations and deletions in Cowden/Bannayan-Riley-Ruvalcaba syndrome result in aberrant PTEN protein and dysregulation of the phosphoinositol-3-kinase/Akt pathway.
    Zhou XP; Waite KA; Pilarski R; Hampel H; Fernandez MJ; Bos C; Dasouki M; Feldman GL; Greenberg LA; Ivanovich J; Matloff E; Patterson A; Pierpont ME; Russo D; Nassif NT; Eng C
    Am J Hum Genet; 2003 Aug; 73(2):404-11. PubMed ID: 12844284
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cowden syndrome-affected patients with PTEN promoter mutations demonstrate abnormal protein translation.
    Teresi RE; Zbuk KM; Pezzolesi MG; Waite KA; Eng C
    Am J Hum Genet; 2007 Oct; 81(4):756-67. PubMed ID: 17847000
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparative genomic and functional analyses reveal a novel cis-acting PTEN regulatory element as a highly conserved functional E-box motif deleted in Cowden syndrome.
    Pezzolesi MG; Zbuk KM; Waite KA; Eng C
    Hum Mol Genet; 2007 May; 16(9):1058-71. PubMed ID: 17341483
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential regulation of PTEN expression by androgen receptor in prostate and breast cancers.
    Wang Y; Romigh T; He X; Tan MH; Orloff MS; Silverman RH; Heston WD; Eng C
    Oncogene; 2011 Oct; 30(42):4327-38. PubMed ID: 21532617
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel mutation of the PTEN gene in a Japanese patient with Cowden syndrome and bilateral breast cancer.
    Tate G; Suzuki T; Endo Y; Mitsuya T
    Cancer Genet Cytogenet; 2008 Jul; 184(1):67-71. PubMed ID: 18558293
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PTEN regulates phospholipase D and phospholipase C.
    Alvarez-Breckenridge CA; Waite KA; Eng C
    Hum Mol Genet; 2007 May; 16(10):1157-63. PubMed ID: 17405772
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Germline epigenetic regulation of KILLIN in Cowden and Cowden-like syndrome.
    Bennett KL; Mester J; Eng C
    JAMA; 2010 Dec; 304(24):2724-31. PubMed ID: 21177507
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Germline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function.
    Lobo GP; Waite KA; Planchon SM; Romigh T; Nassif NT; Eng C
    Hum Mol Genet; 2009 Aug; 18(15):2851-62. PubMed ID: 19457929
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Breast cancer risk and clinical implications for germline PTEN mutation carriers.
    Ngeow J; Sesock K; Eng C
    Breast Cancer Res Treat; 2017 Aug; 165(1):1-8. PubMed ID: 26700035
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Germline mutations and variants in the succinate dehydrogenase genes in Cowden and Cowden-like syndromes.
    Ni Y; Zbuk KM; Sadler T; Patocs A; Lobo G; Edelman E; Platzer P; Orloff MS; Waite KA; Eng C
    Am J Hum Genet; 2008 Aug; 83(2):261-8. PubMed ID: 18678321
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Naturally occurring germline and tumor-associated mutations within the ATP-binding motifs of PTEN lead to oxidative damage of DNA associated with decreased nuclear p53.
    He X; Ni Y; Wang Y; Romigh T; Eng C
    Hum Mol Genet; 2011 Jan; 20(1):80-9. PubMed ID: 20926450
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Germline SDHx variants modify breast and thyroid cancer risks in Cowden and Cowden-like syndrome via FAD/NAD-dependant destabilization of p53.
    Ni Y; He X; Chen J; Moline J; Mester J; Orloff MS; Ringel MD; Eng C
    Hum Mol Genet; 2012 Jan; 21(2):300-10. PubMed ID: 21979946
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Germline PTEN mutations in Cowden syndrome-like families.
    Marsh DJ; Dahia PL; Caron S; Kum JB; Frayling IM; Tomlinson IP; Hughes KS; Eeles RA; Hodgson SV; Murday VA; Houlston R; Eng C
    J Med Genet; 1998 Nov; 35(11):881-5. PubMed ID: 9832031
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PTEN lipid phosphatase activity and proper subcellular localization are necessary and sufficient for down-regulating AKT phosphorylation in the nucleus in Cowden syndrome.
    He X; Saji M; Radhakrishnan D; Romigh T; Ngeow J; Yu Q; Wang Y; Ringel MD; Eng C
    J Clin Endocrinol Metab; 2012 Nov; 97(11):E2179-87. PubMed ID: 22962422
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Utility of PTEN protein dosage in predicting for underlying germline PTEN mutations among patients presenting with thyroid cancer and Cowden-like phenotypes.
    Ngeow J; He X; Mester JL; Lei J; Romigh T; Orloff MS; Milas M; Eng C
    J Clin Endocrinol Metab; 2012 Dec; 97(12):E2320-7. PubMed ID: 23066114
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PTEN autoregulates its expression by stabilization of p53 in a phosphatase-independent manner.
    Tang Y; Eng C
    Cancer Res; 2006 Jan; 66(2):736-42. PubMed ID: 16424003
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of a novel PTEN mutation in MDA-MB-453 breast carcinoma cell line.
    Singh G; Odriozola L; Guan H; Kennedy CR; Chan AM
    BMC Cancer; 2011 Nov; 11():490. PubMed ID: 22103913
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Analysis of PTEN gene mutations in a Turkish patient with Cowden syndrome.
    Soysal Y; Tate G; Polat C; Polat N; Aktepe F; Sivaci Y; Imirzalioglu N
    Genet Test Mol Biomarkers; 2009 Aug; 13(4):547-51. PubMed ID: 19604110
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.