These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 16439135)

  • 1. Chlamydocin analogs bearing carbonyl group as possible ligand toward zinc atom in histone deacetylases.
    Bhuiyan MP; Kato T; Okauchi T; Nishino N; Maeda S; Nishino TG; Yoshida M
    Bioorg Med Chem; 2006 May; 14(10):3438-46. PubMed ID: 16439135
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular design of histone deacetylase inhibitors by aromatic ring shifting in chlamydocin framework.
    Shivashimpi GM; Amagai S; Kato T; Nishino N; Maeda S; Nishino TG; Yoshida M
    Bioorg Med Chem; 2007 Dec; 15(24):7830-9. PubMed ID: 17881232
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chlamydocin-hydroxamic acid analogues as histone deacetylase inhibitors.
    Nishino N; Jose B; Shinta R; Kato T; Komatsu Y; Yoshida M
    Bioorg Med Chem; 2004 Nov; 12(22):5777-84. PubMed ID: 15498654
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction of aliphatic cap group in inhibition of histone deacetylases by cyclic tetrapeptides.
    Nishino N; Shivashimpi GM; Soni PB; Bhuiyan MP; Kato T; Maeda S; Nishino TG; Yoshida M
    Bioorg Med Chem; 2008 Jan; 16(1):437-45. PubMed ID: 17900911
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and histone deacetylase inhibitory activity of cyclic tetrapeptides containing a retrohydroxamate as zinc ligand.
    Nishino N; Yoshikawa D; Watanabe LA; Kato T; Jose B; Komatsu Y; Sumida Y; Yoshida M
    Bioorg Med Chem Lett; 2004 May; 14(10):2427-31. PubMed ID: 15109626
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of functional groups on amino acids in cyclic tetrapeptides in histone deacetylase inhibition.
    Islam MS; Bhuiyan MP; Islam MN; Nsiama TK; Oishi N; Kato T; Nishino N; Ito A; Yoshida M
    Amino Acids; 2012 Jun; 42(6):2103-10. PubMed ID: 21638021
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel histone deacetylase inhibitors: cyclic tetrapeptide with trifluoromethyl and pentafluoroethyl ketones.
    Jose B; Oniki Y; Kato T; Nishino N; Sumida Y; Yoshida M
    Bioorg Med Chem Lett; 2004 Nov; 14(21):5343-6. PubMed ID: 15454224
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis, and evaluation of cyclic amide/imide-bearing hydroxamic acid derivatives as class-selective histone deacetylase (HDAC) inhibitors.
    Shinji C; Maeda S; Imai K; Yoshida M; Hashimoto Y; Miyachi H
    Bioorg Med Chem; 2006 Nov; 14(22):7625-51. PubMed ID: 16877001
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Carbonyl- and sulfur-containing analogs of suberoylanilide hydroxamic acid: Potent inhibition of histone deacetylases.
    Gu W; Nusinzon I; Smith RD; Horvath CM; Silverman RB
    Bioorg Med Chem; 2006 May; 14(10):3320-9. PubMed ID: 16434199
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 2-Trifluoroacetylthiophenes, a novel series of potent and selective class II histone deacetylase inhibitors.
    Jones P; Bottomley MJ; Carfí A; Cecchetti O; Ferrigno F; Lo Surdo P; Ontoria JM; Rowley M; Scarpelli R; Schultz-Fademrecht C; Steinkühler C
    Bioorg Med Chem Lett; 2008 Jun; 18(11):3456-61. PubMed ID: 18440229
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Optimization of a series of potent and selective ketone histone deacetylase inhibitors.
    Pescatore G; Kinzel O; Attenni B; Cecchetti O; Fiore F; Fonsi M; Rowley M; Schultz-Fademrecht C; Serafini S; Steinkühler C; Jones P
    Bioorg Med Chem Lett; 2008 Oct; 18(20):5528-32. PubMed ID: 18809328
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel series of potent and selective ketone histone deacetylase inhibitors with antitumor activity in vivo.
    Jones P; Altamura S; De Francesco R; Paz OG; Kinzel O; Mesiti G; Monteagudo E; Pescatore G; Rowley M; Verdirame M; Steinkühler C
    J Med Chem; 2008 Apr; 51(8):2350-3. PubMed ID: 18370373
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Histone deacetylase inhibitors with a primary amide zinc binding group display antitumor activity in xenograft model.
    Attenni B; Ontoria JM; Cruz JC; Rowley M; Schultz-Fademrecht C; Steinkühler C; Jones P
    Bioorg Med Chem Lett; 2009 Jun; 19(11):3081-4. PubMed ID: 19410459
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A series of novel, potent, and selective histone deacetylase inhibitors.
    Jones P; Altamura S; Chakravarty PK; Cecchetti O; De Francesco R; Gallinari P; Ingenito R; Meinke PT; Petrocchi A; Rowley M; Scarpelli R; Serafini S; Steinkühler C
    Bioorg Med Chem Lett; 2006 Dec; 16(23):5948-52. PubMed ID: 16987657
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design and synthesis of cyclopeptide analogues of the potent histone deacetylase inhibitor FR235222.
    Gomez-Paloma L; Bruno I; Cini E; Khochbin S; Rodriquez M; Taddei M; Terracciano S; Sadoul K
    ChemMedChem; 2007 Oct; 2(10):1511-9. PubMed ID: 17694590
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Total synthesis, NMR solution structure, and binding model of the potent histone deacetylase inhibitor FR235222.
    Rodriquez M; Terracciano S; Cini E; Settembrini G; Bruno I; Bifulco G; Taddei M; Gomez-Paloma L
    Angew Chem Int Ed Engl; 2006 Jan; 45(3):423-7. PubMed ID: 16311994
    [No Abstract]   [Full Text] [Related]  

  • 17. Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin.
    Furumai R; Komatsu Y; Nishino N; Khochbin S; Yoshida M; Horinouchi S
    Proc Natl Acad Sci U S A; 2001 Jan; 98(1):87-92. PubMed ID: 11134513
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design and synthesis of a potent histone deacetylase inhibitor.
    Liu T; Kapustin G; Etzkorn FA
    J Med Chem; 2007 May; 50(9):2003-6. PubMed ID: 17419603
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Toward an HDAC6 inhibitor: synthesis and conformational analysis of cyclic hexapeptide hydroxamic acid designed from alpha-tubulin sequence.
    Jose B; Okamura S; Kato T; Nishino N; Sumida Y; Yoshida M
    Bioorg Med Chem; 2004 Mar; 12(6):1351-6. PubMed ID: 15018907
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, biological evaluation, and molecular docking of Ugi products containing a zinc-chelating moiety as novel inhibitors of histone deacetylases.
    Grolla AA; Podestà V; Chini MG; Di Micco S; Vallario A; Genazzani AA; Canonico PL; Bifulco G; Tron GC; Sorba G; Pirali T
    J Med Chem; 2009 May; 52(9):2776-85. PubMed ID: 19344175
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.