652 related articles for article (PubMed ID: 16439544)
1. Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus.
Vandekerckhove L; Christ F; Van Maele B; De Rijck J; Gijsbers R; Van den Haute C; Witvrouw M; Debyser Z
J Virol; 2006 Feb; 80(4):1886-96. PubMed ID: 16439544
[TBL] [Abstract][Full Text] [Related]
2. Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV.
Hombrouck A; De Rijck J; Hendrix J; Vandekerckhove L; Voet A; De Maeyer M; Witvrouw M; Engelborghs Y; Christ F; Gijsbers R; Debyser Z
PLoS Pathog; 2007 Mar; 3(3):e47. PubMed ID: 17397262
[TBL] [Abstract][Full Text] [Related]
3. An essential role for LEDGF/p75 in HIV integration.
Llano M; Saenz DT; Meehan A; Wongthida P; Peretz M; Walker WH; Teo W; Poeschla EM
Science; 2006 Oct; 314(5798):461-4. PubMed ID: 16959972
[TBL] [Abstract][Full Text] [Related]
4. Identification of the LEDGF/p75 binding site in HIV-1 integrase.
Busschots K; Voet A; De Maeyer M; Rain JC; Emiliani S; Benarous R; Desender L; Debyser Z; Christ F
J Mol Biol; 2007 Feb; 365(5):1480-92. PubMed ID: 17137594
[TBL] [Abstract][Full Text] [Related]
5. Biochemical and genetic analyses of integrase-interacting proteins lens epithelium-derived growth factor (LEDGF)/p75 and hepatoma-derived growth factor related protein 2 (HRP2) in preintegration complex function and HIV-1 replication.
Vandegraaff N; Devroe E; Turlure F; Silver PA; Engelman A
Virology; 2006 Mar; 346(2):415-26. PubMed ID: 16337983
[TBL] [Abstract][Full Text] [Related]
6. Overexpression of the lens epithelium-derived growth factor/p75 integrase binding domain inhibits human immunodeficiency virus replication.
De Rijck J; Vandekerckhove L; Gijsbers R; Hombrouck A; Hendrix J; Vercammen J; Engelborghs Y; Christ F; Debyser Z
J Virol; 2006 Dec; 80(23):11498-509. PubMed ID: 16987986
[TBL] [Abstract][Full Text] [Related]
7. Differential interaction of HIV-1 integrase and JPO2 with the C terminus of LEDGF/p75.
Bartholomeeusen K; De Rijck J; Busschots K; Desender L; Gijsbers R; Emiliani S; Benarous R; Debyser Z; Christ F
J Mol Biol; 2007 Sep; 372(2):407-21. PubMed ID: 17669426
[TBL] [Abstract][Full Text] [Related]
8. D77, one benzoic acid derivative, functions as a novel anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75.
Du L; Zhao Y; Chen J; Yang L; Zheng Y; Tang Y; Shen X; Jiang H
Biochem Biophys Res Commun; 2008 Oct; 375(1):139-44. PubMed ID: 18691555
[TBL] [Abstract][Full Text] [Related]
9. Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLS-independent chromatin tethering.
Vanegas M; Llano M; Delgado S; Thompson D; Peretz M; Poeschla E
J Cell Sci; 2005 Apr; 118(Pt 8):1733-43. PubMed ID: 15797927
[TBL] [Abstract][Full Text] [Related]
10. Structure-based mutagenesis of the integrase-LEDGF/p75 interface uncouples a strict correlation between in vitro protein binding and HIV-1 fitness.
Rahman S; Lu R; Vandegraaff N; Cherepanov P; Engelman A
Virology; 2007 Jan; 357(1):79-90. PubMed ID: 16959283
[TBL] [Abstract][Full Text] [Related]
11. Characterization of rare lens epithelium-derived growth factor/p75 genetic variants identified in HIV-1 long-term nonprogressors.
Schrijvers R; Demeulemeester J; De Rijck J; Christ F; Gérard M; Debyser Z; Gijsbers R
AIDS; 2013 Feb; 27(4):539-43. PubMed ID: 23211777
[TBL] [Abstract][Full Text] [Related]
12. Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: insight into integrase-DNA complex formation and catalysis.
Al-Mawsawi LQ; Christ F; Dayam R; Debyser Z; Neamati N
FEBS Lett; 2008 Apr; 582(10):1425-30. PubMed ID: 18331842
[TBL] [Abstract][Full Text] [Related]
13. LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes.
Llano M; Vanegas M; Fregoso O; Saenz D; Chung S; Peretz M; Poeschla EM
J Virol; 2004 Sep; 78(17):9524-37. PubMed ID: 15308744
[TBL] [Abstract][Full Text] [Related]
14. Peptides derived from the HIV-1 integrase promote HIV-1 infection and multi-integration of viral cDNA in LEDGF/p75-knockdown cells.
Levin A; Hayouka Z; Friedler A; Loyter A
Virol J; 2010 Aug; 7():177. PubMed ID: 20678206
[TBL] [Abstract][Full Text] [Related]
15. The LEDGF/p75 integrase interaction, a novel target for anti-HIV therapy.
Christ F; Debyser Z
Virology; 2013 Jan; 435(1):102-9. PubMed ID: 23217620
[TBL] [Abstract][Full Text] [Related]
16. Transcriptional coactivator LEDGF/p75 modulates human immunodeficiency virus type 1 integrase-mediated concerted integration.
Pandey KK; Sinha S; Grandgenett DP
J Virol; 2007 Apr; 81(8):3969-79. PubMed ID: 17267486
[TBL] [Abstract][Full Text] [Related]
17. In vitro DNA tethering of HIV-1 integrase by the transcriptional coactivator LEDGF/p75.
McNeely M; Hendrix J; Busschots K; Boons E; Deleersnijder A; Gerard M; Christ F; Debyser Z
J Mol Biol; 2011 Jul; 410(5):811-30. PubMed ID: 21763490
[TBL] [Abstract][Full Text] [Related]
18. The Structure-Specific Recognition Protein 1 Associates with Lens Epithelium-Derived Growth Factor Proteins and Modulates HIV-1 Replication.
Lopez AP; Kugelman JR; Garcia-Rivera J; Urias E; Salinas SA; Fernandez-Zapico ME; Llano M
J Mol Biol; 2016 Jul; 428(14):2814-31. PubMed ID: 27216501
[TBL] [Abstract][Full Text] [Related]
19. Structure-based virtual screening toward the discovery of novel inhibitors for impeding the protein-protein interaction between HIV-1 integrase and human lens epithelium-derived growth factor (LEDGF/p75).
Panwar U; Singh SK
J Biomol Struct Dyn; 2018 Sep; 36(12):3199-3217. PubMed ID: 28948865
[TBL] [Abstract][Full Text] [Related]
20. Pharmacophore-based discovery of small-molecule inhibitors of protein-protein interactions between HIV-1 integrase and cellular cofactor LEDGF/p75.
De Luca L; Barreca ML; Ferro S; Christ F; Iraci N; Gitto R; Monforte AM; Debyser Z; Chimirri A
ChemMedChem; 2009 Aug; 4(8):1311-6. PubMed ID: 19565598
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
