These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
113 related articles for article (PubMed ID: 16442274)
21. Screening of potential a disintegrin and metalloproteinase with thrombospondin motifs-4 inhibitors using a collagen model fluorescence resonance energy transfer substrate. Lauer-Fields JL; Spicer TP; Chase PS; Cudic M; Burstein GD; Nagase H; Hodder P; Fields GB Anal Biochem; 2008 Feb; 373(1):43-51. PubMed ID: 17949675 [TBL] [Abstract][Full Text] [Related]
22. Arylsulfonamide inhibitors of aggrecanases as potential therapeutic agents for osteoarthritis: synthesis and biological evaluation. Nuti E; Santamaria S; Casalini F; Yamamoto K; Marinelli L; La Pietra V; Novellino E; Orlandini E; Nencetti S; Marini AM; Salerno S; Taliani S; Da Settimo F; Nagase H; Rossello A Eur J Med Chem; 2013 Apr; 62():379-94. PubMed ID: 23376997 [TBL] [Abstract][Full Text] [Related]
23. The nutraceutical flavonoid luteolin inhibits ADAMTS-4 and ADAMTS-5 aggrecanase activities. Moncada-Pazos A; Obaya AJ; Viloria CG; López-Otín C; Cal S J Mol Med (Berl); 2011 Jun; 89(6):611-9. PubMed ID: 21365186 [TBL] [Abstract][Full Text] [Related]
24. Truncation of the amino-terminus of the recombinant aggrecan rAgg1mut leads to reduced cleavage at the aggrecanase site. Efficient aggrecanase catabolism may depend on multiple substrate interactions. Hörber C; Büttner FH; Kern C; Schmiedeknecht G; Bartnik E Matrix Biol; 2000 Nov; 19(6):533-43. PubMed ID: 11068207 [TBL] [Abstract][Full Text] [Related]
25. Drug insight: aggrecanases as therapeutic targets for osteoarthritis. Fosang AJ; Little CB Nat Clin Pract Rheumatol; 2008 Aug; 4(8):420-7. PubMed ID: 18577998 [TBL] [Abstract][Full Text] [Related]
26. A quantitative assay for aggrecanase activity. Will H; Dettloff M; Bendzkô P; Sveshnikov P J Biomol Tech; 2005 Dec; 16(4):459-72. PubMed ID: 16522869 [TBL] [Abstract][Full Text] [Related]
27. The development and characterization of a competitive ELISA for measuring active ADAMTS-4 in a bovine cartilage ex vivo model. He Y; Zheng Q; Simonsen O; Petersen KK; Christiansen TG; Karsdal MA; Bay-Jensen AC Matrix Biol; 2013 Apr; 32(3-4):143-51. PubMed ID: 23295731 [TBL] [Abstract][Full Text] [Related]
28. Synthesis and biological evaluation of biphenylsulfonamide carboxylate aggrecanase-1 inhibitors. Xiang JS; Hu Y; Rush TS; Thomason JR; Ipek M; Sum PE; Abrous L; Sabatini JJ; Georgiadis K; Reifenberg E; Majumdar M; Morris EA; Tam S Bioorg Med Chem Lett; 2006 Jan; 16(2):311-6. PubMed ID: 16275085 [TBL] [Abstract][Full Text] [Related]
29. Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases. Troeberg L; Fushimi K; Khokha R; Emonard H; Ghosh P; Nagase H FASEB J; 2008 Oct; 22(10):3515-24. PubMed ID: 18632849 [TBL] [Abstract][Full Text] [Related]
30. Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5. Song RH; Tortorella MD; Malfait AM; Alston JT; Yang Z; Arner EC; Griggs DW Arthritis Rheum; 2007 Feb; 56(2):575-85. PubMed ID: 17265492 [TBL] [Abstract][Full Text] [Related]
31. Current and emerging therapeutic strategies for preventing inflammation and aggrecanase-mediated cartilage destruction in arthritis. Dancevic CM; McCulloch DR Arthritis Res Ther; 2014; 16(5):429. PubMed ID: 25606593 [TBL] [Abstract][Full Text] [Related]
32. Effects of RNAi-mediated inhibition of aggrecanase-1 and aggrecanase-2 on rat costochondral chondrocytes in vitro. Wang ZH; Yang ZQ; He XJ; Wang L; Li LX; Tu JB Acta Pharmacol Sin; 2008 Oct; 29(10):1215-26. PubMed ID: 18817627 [TBL] [Abstract][Full Text] [Related]
33. Variations in aggrecan structure modulate its susceptibility to aggrecanases. Roughley PJ; Barnett J; Zuo F; Mort JS Biochem J; 2003 Oct; 375(Pt 1):183-9. PubMed ID: 12859252 [TBL] [Abstract][Full Text] [Related]
34. Thyroid hormone enhances aggrecanase-2/ADAM-TS5 expression and proteoglycan degradation in growth plate cartilage. Makihira S; Yan W; Murakami H; Furukawa M; Kawai T; Nikawa H; Yoshida E; Hamada T; Okada Y; Kato Y Endocrinology; 2003 Jun; 144(6):2480-8. PubMed ID: 12746310 [TBL] [Abstract][Full Text] [Related]
35. Synthesis and biological evaluation of ((4-keto)-phenoxy)methyl biphenyl-4-sulfonamides: a class of potent aggrecanase-1 inhibitors. Hopper DW; Vera MD; How D; Sabatini J; Xiang JS; Ipek M; Thomason J; Hu Y; Feyfant E; Wang Q; Georgiadis KE; Reifenberg E; Sheldon RT; Keohan CC; Majumdar MK; Morris EA; Skotnicki J; Sum PE Bioorg Med Chem Lett; 2009 May; 19(9):2487-91. PubMed ID: 19329309 [TBL] [Abstract][Full Text] [Related]
36. The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation. Tortorella MD; Malfait AM; Deccico C; Arner E Osteoarthritis Cartilage; 2001 Aug; 9(6):539-52. PubMed ID: 11520168 [TBL] [Abstract][Full Text] [Related]
37. Effects of transforming growth factor-beta on aggrecanase production and proteoglycan degradation by human chondrocytes in vitro. Moulharat N; Lesur C; Thomas M; Rolland-Valognes G; Pastoureau P; Anract P; De Ceuninck F; Sabatini M Osteoarthritis Cartilage; 2004 Apr; 12(4):296-305. PubMed ID: 15023381 [TBL] [Abstract][Full Text] [Related]
38. Reactive-site mutants of N-TIMP-3 that selectively inhibit ADAMTS-4 and ADAMTS-5: biological and structural implications. Lim NH; Kashiwagi M; Visse R; Jones J; Enghild JJ; Brew K; Nagase H Biochem J; 2010 Oct; 431(1):113-22. PubMed ID: 20645923 [TBL] [Abstract][Full Text] [Related]
39. Removal of O-linked and N-linked oligosaccharides is required for optimum detection of NITEGE neoepitope on ADAMTS4-digested fetal aggrecans: implications for specific N-linked glycan-dependent aggrecanolysis at Glu373-Ala374. Frank JE; Thompson VP; Brown MP; Sandy JD Osteoarthritis Cartilage; 2009 Jun; 17(6):777-81. PubMed ID: 19071032 [TBL] [Abstract][Full Text] [Related]
40. Neoepitope antibodies against MMP-cleaved and aggrecanase-cleaved aggrecan. Fosang AJ; Last K; Stanton H; Golub SB; Little CB; Brown L; Jackson DC Methods Mol Biol; 2010; 622():312-47. PubMed ID: 20135291 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]