95 related articles for article (PubMed ID: 16446090)
21. Synthesis and biological evaluation of 3-ethylidene-1,3-dihydro-indol-2-ones as novel checkpoint 1 inhibitors.
Lin NH; Xia P; Kovar P; Park C; Chen Z; Zhang H; Rosenberg SH; Sham HL
Bioorg Med Chem Lett; 2006 Jan; 16(2):421-6. PubMed ID: 16242328
[TBL] [Abstract][Full Text] [Related]
22. Identification of inhibitors of checkpoint kinase 1 through template screening.
Matthews TP; Klair S; Burns S; Boxall K; Cherry M; Fisher M; Westwood IM; Walton MI; McHardy T; Cheung KM; Van Montfort R; Williams D; Aherne GW; Garrett MD; Reader J; Collins I
J Med Chem; 2009 Aug; 52(15):4810-9. PubMed ID: 19572549
[TBL] [Abstract][Full Text] [Related]
23. Discovery of a novel class of triazolones as checkpoint kinase inhibitors--hit to lead exploration.
Oza V; Ashwell S; Brassil P; Breed J; Deng C; Ezhuthachan J; Haye H; Horn C; Janetka J; Lyne P; Newcombe N; Otterbien L; Pass M; Read J; Roswell S; Su M; Toader D; Yu D; Yu Y; Valentine A; Webborn P; White A; Zabludoff S; Zheng X
Bioorg Med Chem Lett; 2010 Sep; 20(17):5133-8. PubMed ID: 20673630
[TBL] [Abstract][Full Text] [Related]
24. Synthesis and evaluation of substituted benzoisoquinolinones as potent inhibitors of Chk1 kinase.
Garbaccio RM; Huang S; Tasber ES; Fraley ME; Yan Y; Munshi S; Ikuta M; Kuo L; Kreatsoulas C; Stirdivant S; Drakas B; Rickert K; Walsh ES; Hamilton KA; Buser CA; Hardwick J; Mao X; Beck SC; Abrams MT; Tao W; Lobell R; Sepp-Lorenzino L; Hartman GD
Bioorg Med Chem Lett; 2007 Nov; 17(22):6280-5. PubMed ID: 17900896
[TBL] [Abstract][Full Text] [Related]
25. Synthesis and biological evaluation of new 3-(6-hydroxyindol-2-yl)-5-(Phenyl) pyridine or pyrazine V-Shaped molecules as kinase inhibitors and cytotoxic agents.
Kassis P; Brzeszcz J; Bénéteau V; Lozach O; Meijer L; Le Guével R; Guillouzo C; Lewiński K; Bourg S; Colliandre L; Routier S; Mérour JY
Eur J Med Chem; 2011 Nov; 46(11):5416-34. PubMed ID: 21944287
[TBL] [Abstract][Full Text] [Related]
26. Synthesis and biological activities of new checkpoint kinase 1 inhibitors structurally related to granulatimide.
Conchon E; Anizon F; Aboab B; Prudhomme M
J Med Chem; 2007 Sep; 50(19):4669-80. PubMed ID: 17722905
[TBL] [Abstract][Full Text] [Related]
27. Kinase drug discovery by affinity selection/mass spectrometry (ASMS): application to DNA damage checkpoint kinase Chk1.
Comess KM; Trumbull JD; Park C; Chen Z; Judge RA; Voorbach MJ; Coen M; Gao L; Tang H; Kovar P; Cheng X; Schurdak ME; Zhang H; Sowin T; Burns DJ
J Biomol Screen; 2006 Oct; 11(7):755-64. PubMed ID: 16956998
[TBL] [Abstract][Full Text] [Related]
28. Carcinogen-induced S-phase arrest is Chk1 mediated and caffeine sensitive.
Guo N; Faller DV; Vaziri C
Cell Growth Differ; 2002 Feb; 13(2):77-86. PubMed ID: 11864911
[TBL] [Abstract][Full Text] [Related]
29. Novel 5-azaindolocarbazoles as cytotoxic agents and Chk1 inhibitors.
Lefoix M; Coudert G; Routier S; Pfeiffer B; Caignard DH; Hickman J; Pierré A; Golsteyn RM; Léonce S; Bossard C; Mérour JY
Bioorg Med Chem; 2008 May; 16(9):5303-21. PubMed ID: 18342518
[TBL] [Abstract][Full Text] [Related]
30. Novel inhibitors of checkpoint kinase 1.
Arrington KL; Dudkin VY
ChemMedChem; 2007 Nov; 2(11):1571-85. PubMed ID: 17854022
[No Abstract] [Full Text] [Related]
31. 4-(Aminoalkylamino)-3-benzimidazole-quinolinones as potent CHK-1 inhibitors.
Ni ZJ; Barsanti P; Brammeier N; Diebes A; Poon DJ; Ng S; Pecchi S; Pfister K; Renhowe PA; Ramurthy S; Wagman AS; Bussiere DE; Le V; Zhou Y; Jansen JM; Ma S; Gesner TG
Bioorg Med Chem Lett; 2006 Jun; 16(12):3121-4. PubMed ID: 16603354
[TBL] [Abstract][Full Text] [Related]
32. Development of a screening assay for surrogate markers of CHK1 inhibitor-induced cell cycle release.
Fanton CP; Rowe MW; Moler EJ; Ison-Dugenny M; De Long SK; Rendahl K; Shao Y; Slabiak T; Gesner TG; MacKichan ML
J Biomol Screen; 2006 Oct; 11(7):792-806. PubMed ID: 17035625
[TBL] [Abstract][Full Text] [Related]
33. Synthesis and biological evaluation of di-aryl urea derivatives as c-Kit inhibitors.
Ravez S; Arsenlis S; Barczyk A; Dupont A; Frédérick R; Hesse S; Kirsch G; Depreux P; Goossens L
Bioorg Med Chem; 2015 Nov; 23(22):7340-7. PubMed ID: 26526740
[TBL] [Abstract][Full Text] [Related]
34. N-Phenyl-N-purin-6-yl ureas: the design and synthesis of p38alpha MAP kinase inhibitors.
Wan Z; Boehm JC; Bower MJ; Kassis S; Lee JC; Zhao B; Adams JL
Bioorg Med Chem Lett; 2003 Mar; 13(6):1191-4. PubMed ID: 12643941
[TBL] [Abstract][Full Text] [Related]
35. Synthesis and evaluation of debromohymenialdisine-derived Chk2 inhibitors.
Saleem RS; Lansdell TA; Tepe JJ
Bioorg Med Chem; 2012 Feb; 20(4):1475-81. PubMed ID: 22285028
[TBL] [Abstract][Full Text] [Related]
36. Synthesis and structure-activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases.
Smaill JB; Lee HH; Palmer BD; Thompson AM; Squire CJ; Baker EN; Booth RJ; Kraker A; Hook K; Denny WA
Bioorg Med Chem Lett; 2008 Feb; 18(3):929-33. PubMed ID: 18191399
[TBL] [Abstract][Full Text] [Related]
37. 4-Quinazolinyloxy-diaryl ureas as novel BRAFV600E inhibitors.
Holladay MW; Campbell BT; Rowbottom MW; Chao Q; Sprankle KG; Lai AG; Abraham S; Setti E; Faraoni R; Tran L; Armstrong RC; Gunawardane RN; Gardner MF; Cramer MD; Gitnick D; Ator MA; Dorsey BD; Ruggeri BR; Williams M; Bhagwat SS; James J
Bioorg Med Chem Lett; 2011 Sep; 21(18):5342-6. PubMed ID: 21807507
[TBL] [Abstract][Full Text] [Related]
38. Design, synthesis and evaluation of novel diaryl urea derivatives as potential antitumor agents.
Lu C; Tang K; Li Y; Li P; Lin Z; Yin D; Chen X; Huang H
Eur J Med Chem; 2014 Apr; 77():351-60. PubMed ID: 24675135
[TBL] [Abstract][Full Text] [Related]
39. Design and evaluation of 3,6-di(hetero)aryl imidazo[1,2-a]pyrazines as inhibitors of checkpoint and other kinases.
Matthews TP; McHardy T; Klair S; Boxall K; Fisher M; Cherry M; Allen CE; Addison GJ; Ellard J; Aherne GW; Westwood IM; van Montfort R; Garrett MD; Reader JC; Collins I
Bioorg Med Chem Lett; 2010 Jul; 20(14):4045-9. PubMed ID: 20561787
[TBL] [Abstract][Full Text] [Related]
40. Identification of novel aminothiazole and aminothiadiazole conjugated cyanopyridines as selective CHK1 inhibitors.
Gomha SM; Abdulla MM; Abou-Seri SM
Eur J Med Chem; 2015 Mar; 92():459-70. PubMed ID: 25594740
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]