BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

509 related articles for article (PubMed ID: 16449235)

  • 1. Impaired helix 12 dynamics due to proline 892 substitutions in the androgen receptor are associated with complete androgen insensitivity.
    Elhaji YA; Stoica I; Dennis S; Purisima EO; Lumbroso R; Beitel LK; Trifiro MA
    Hum Mol Genet; 2006 Mar; 15(6):921-31. PubMed ID: 16449235
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Partial androgen insensitivity with phenotypic variation caused by androgen receptor mutations that disrupt activation function 2 and the NH(2)- and carboxyl-terminal interaction.
    Quigley CA; Tan JA; He B; Zhou ZX; Mebarki F; Morel Y; Forest MG; Chatelain P; Ritzén EM; French FS; Wilson EM
    Mech Ageing Dev; 2004; 125(10-11):683-95. PubMed ID: 15541764
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bridging structural biology and genetics by computational methods: an investigation into how the R774C mutation in the AR gene can result in complete androgen insensitivity syndrome.
    Wu JH; Gottlieb B; Batist G; Sulea T; Purisima EO; Beitel LK; Trifiro M
    Hum Mutat; 2003 Dec; 22(6):465-75. PubMed ID: 14635106
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel mutation F826L in the human androgen receptor in partial androgen insensitivity syndrome; increased NH2-/COOH-terminal domain interaction and TIF2 co-activation.
    Wong HY; Hoogerbrugge JW; Pang KL; van Leeuwen M; van Royen ME; Molier M; Berrevoets CA; Dooijes D; Dubbink HJ; van de Wijngaart DJ; Wolffenbuttel KP; Trapman J; Kleijer WJ; Drop SL; Grootegoed JA; Brinkmann AO
    Mol Cell Endocrinol; 2008 Sep; 292(1-2):69-78. PubMed ID: 18656523
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Five novel androgen receptor gene mutations associated with complete androgen insensitivity syndrome.
    Jääskeläinen J; Mongan NP; Harland S; Hughes IA
    Hum Mutat; 2006 Mar; 27(3):291. PubMed ID: 16470553
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An examination of how different mutations at arginine 855 of the androgen receptor result in different androgen insensitivity phenotypes.
    Elhaji YA; Wu JH; Gottlieb B; Beitel LK; Alvarado C; Batist G; Trifiro MA
    Mol Endocrinol; 2004 Aug; 18(8):1876-86. PubMed ID: 15118070
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparison of the molecular consequences of different mutations at residue 754 and 690 of the androgen receptor (AR) and androgen insensitivity syndrome (AIS) phenotype.
    Tadokoro R; Bunch T; Schwabe JW; Hughes IA; Murphy JC
    Clin Endocrinol (Oxf); 2009 Aug; 71(2):253-60. PubMed ID: 19178528
    [TBL] [Abstract][Full Text] [Related]  

  • 8. L859F mutation in androgen receptor gene results in complete loss of androgen binding to the receptor.
    Rajender S; Singh L; Thangaraj K
    J Androl; 2007; 28(5):772-6. PubMed ID: 17522416
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Study of the impact of the T877A mutation on ligand-induced helix-12 positioning of the androgen receptor resulted in design and synthesis of novel antiandrogens.
    Zhou J; Liu B; Geng G; Wu JH
    Proteins; 2010 Feb; 78(3):623-37. PubMed ID: 19787772
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human androgen insensitivity due to point mutations encoding amino acid substitutions in the androgen receptor steroid-binding domain.
    Murono K; Mendonca BB; Arnhold IJ; Rigon AC; Migeon CJ; Brown TR
    Hum Mutat; 1995; 6(2):152-62. PubMed ID: 7581399
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Impaired nuclear translocation, nuclear matrix targeting, and intranuclear mobility of mutant androgen receptors carrying amino acid substitutions in the deoxyribonucleic acid-binding domain derived from androgen insensitivity syndrome patients.
    Kawate H; Wu Y; Ohnaka K; Tao RH; Nakamura K; Okabe T; Yanase T; Nawata H; Takayanagi R
    J Clin Endocrinol Metab; 2005 Nov; 90(11):6162-9. PubMed ID: 16118342
    [TBL] [Abstract][Full Text] [Related]  

  • 12. G708E mutation in the androgen receptor results in complete loss of androgen function.
    Rajender S; Pooja S; Gupta NJ; Chakrabarty B; Singh L; Thangaraj K
    J Androl; 2011; 32(2):193-8. PubMed ID: 20671138
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ala 586 Asp mutation in androgen receptor disrupts transactivation function without affecting androgen binding.
    Rajender S; Gupta NJ; Chakrabarty B; Singh L; Thangaraj K
    Fertil Steril; 2009 Mar; 91(3):933.e23-8. PubMed ID: 19062009
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The androgen receptor T877A mutant recruits LXXLL and FXXLF peptides differently than wild-type androgen receptor in a time-resolved fluorescence resonance energy transfer assay.
    Ozers MS; Marks BD; Gowda K; Kupcho KR; Ervin KM; De Rosier T; Qadir N; Eliason HC; Riddle SM; Shekhani MS
    Biochemistry; 2007 Jan; 46(3):683-95. PubMed ID: 17223690
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional in vivo interaction between the amino-terminal, transactivation domain and the ligand binding domain of the androgen receptor.
    Doesburg P; Kuil CW; Berrevoets CA; Steketee K; Faber PW; Mulder E; Brinkmann AO; Trapman J
    Biochemistry; 1997 Feb; 36(5):1052-64. PubMed ID: 9033395
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Leu-676-Pro mutation of the androgen receptor causes complete androgen insensitivity syndrome in a large Hutterite kindred.
    Belsham DD; Pereira F; Greenberg CR; Liao S; Wrogemann K
    Hum Mutat; 1995; 5(1):28-33. PubMed ID: 7537149
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel mutation in the ligand-binding domain of the androgen receptor gene (l790p) associated with complete androgen insensitivity syndrome.
    Raicu F; Giuliani R; Gatta V; Palka C; Franchi PG; Lelli-Chiesa P; Tumini S; Stuppia L
    Asian J Androl; 2008 Jul; 10(4):687-91. PubMed ID: 18097502
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutations in the amino-terminal domain of the human androgen receptor may be associated with partial androgen insensitivity and impaired transactivation in vitro.
    Holterhus PM; Werner R; Struve D; Hauffa BP; Schroeder C; Hiort O
    Exp Clin Endocrinol Diabetes; 2005 Sep; 113(8):457-63. PubMed ID: 16151980
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel androgen receptor gene mutations in Australian patients with complete androgen insensitivity syndrome.
    MacLean HE; Ball EM; Rekaris G; Warne GL; Zajac JD
    Hum Mutat; 2004 Mar; 23(3):287. PubMed ID: 14974091
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Mutation analysis of the androgen receptor gene in a complete androgen insensitivity syndrome family].
    Wu W; Luo F; Geng Q; Hao Y; Chen W; Cai J; Xie J
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2009 Dec; 26(6):606-9. PubMed ID: 19953479
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.