These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

481 related articles for article (PubMed ID: 16449638)

  • 1. CAND1-mediated substrate adaptor recycling is required for efficient repression of Nrf2 by Keap1.
    Lo SC; Hannink M
    Mol Cell Biol; 2006 Feb; 26(4):1235-44. PubMed ID: 16449638
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.
    Zhang DD; Lo SC; Cross JV; Templeton DJ; Hannink M
    Mol Cell Biol; 2004 Dec; 24(24):10941-53. PubMed ID: 15572695
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases.
    Villeneuve NF; Lau A; Zhang DD
    Antioxid Redox Signal; 2010 Dec; 13(11):1699-712. PubMed ID: 20486766
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.
    Kobayashi A; Kang MI; Okawa H; Ohtsuji M; Zenke Y; Chiba T; Igarashi K; Yamamoto M
    Mol Cell Biol; 2004 Aug; 24(16):7130-9. PubMed ID: 15282312
    [TBL] [Abstract][Full Text] [Related]  

  • 5. BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.
    Furukawa M; Xiong Y
    Mol Cell Biol; 2005 Jan; 25(1):162-71. PubMed ID: 15601839
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Zinc-binding triggers a conformational-switch in the cullin-3 substrate adaptor protein KEAP1 that controls transcription factor NRF2.
    McMahon M; Swift SR; Hayes JD
    Toxicol Appl Pharmacol; 2018 Dec; 360():45-57. PubMed ID: 30261176
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway.
    Zhang DD; Lo SC; Sun Z; Habib GM; Lieberman MW; Hannink M
    J Biol Chem; 2005 Aug; 280(34):30091-9. PubMed ID: 15983046
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2.
    Sun Z; Zhang S; Chan JY; Zhang DD
    Mol Cell Biol; 2007 Sep; 27(18):6334-49. PubMed ID: 17636022
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase.
    Cullinan SB; Gordan JD; Jin J; Harper JW; Diehl JA
    Mol Cell Biol; 2004 Oct; 24(19):8477-86. PubMed ID: 15367669
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CAND1 exchange factor promotes Keap1 integration into cullin 3-RING ubiquitin ligase during adipogenesis.
    Dubiel D; Ordemann J; Pratschke J; Dubiel W; Naumann M
    Int J Biochem Cell Biol; 2015 Sep; 66():95-100. PubMed ID: 26219975
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62.
    Lau A; Wang XJ; Zhao F; Villeneuve NF; Wu T; Jiang T; Sun Z; White E; Zhang DD
    Mol Cell Biol; 2010 Jul; 30(13):3275-85. PubMed ID: 20421418
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Drosophila Cand1 regulates Cullin3-dependent E3 ligases by affecting the neddylation of Cullin3 and by controlling the stability of Cullin3 and adaptor protein.
    Kim SH; Kim HJ; Kim S; Yim J
    Dev Biol; 2010 Oct; 346(2):247-57. PubMed ID: 20691177
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Keap1-Nrf2 system as an in vivo sensor for electrophiles.
    Uruno A; Motohashi H
    Nitric Oxide; 2011 Aug; 25(2):153-60. PubMed ID: 21385624
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells.
    Iso T; Suzuki T; Baird L; Yamamoto M
    Mol Cell Biol; 2016 Dec; 36(24):3100-3112. PubMed ID: 27697860
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CRL3s: The BTB-CUL3-RING E3 Ubiquitin Ligases.
    Wang P; Song J; Ye D
    Adv Exp Med Biol; 2020; 1217():211-223. PubMed ID: 31898230
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CACUL1/CAC1 Regulates the Antioxidant Response by Stabilizing Nrf2.
    Kigoshi Y; Fukuda T; Endo T; Hayasaka N; Iemura S; Natsume T; Tsuruta F; Chiba T
    Sci Rep; 2015 Aug; 5():12857. PubMed ID: 26238671
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway.
    Hayes JD; McMahon M; Chowdhry S; Dinkova-Kostova AT
    Antioxid Redox Signal; 2010 Dec; 13(11):1713-48. PubMed ID: 20446772
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PGAM5, a Bcl-XL-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex.
    Lo SC; Hannink M
    J Biol Chem; 2006 Dec; 281(49):37893-903. PubMed ID: 17046835
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The gasotransmitter hydrogen sulfide induces nrf2-target genes by inactivating the keap1 ubiquitin ligase substrate adaptor through formation of a disulfide bond between cys-226 and cys-613.
    Hourihan JM; Kenna JG; Hayes JD
    Antioxid Redox Signal; 2013 Aug; 19(5):465-81. PubMed ID: 23145493
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antioxidant-induced INrf2 (Keap1) tyrosine 85 phosphorylation controls the nuclear export and degradation of the INrf2-Cul3-Rbx1 complex to allow normal Nrf2 activation and repression.
    Kaspar JW; Niture SK; Jaiswal AK
    J Cell Sci; 2012 Feb; 125(Pt 4):1027-38. PubMed ID: 22448038
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.