405 related articles for article (PubMed ID: 16451055)
1. Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole.
Benaim G; Sanders JM; Garcia-Marchán Y; Colina C; Lira R; Caldera AR; Payares G; Sanoja C; Burgos JM; Leon-Rossell A; Concepcion JL; Schijman AG; Levin M; Oldfield E; Urbina JA
J Med Chem; 2006 Feb; 49(3):892-9. PubMed ID: 16451055
[TBL] [Abstract][Full Text] [Related]
2. Targeting calcium homeostasis as the therapy of Chagas' disease and leishmaniasis - a review.
Benaim B; Garcia CR
Trop Biomed; 2011 Dec; 28(3):471-81. PubMed ID: 22433874
[TBL] [Abstract][Full Text] [Related]
3. Anti-Trypanosoma cruzi action of a new benzofuran derivative based on amiodarone structure.
Pinto-Martinez A; Hernández-Rodríguez V; Rodríguez-Durán J; Hejchman E; Benaim G
Exp Parasitol; 2018 Jun; 189():8-15. PubMed ID: 29684665
[TBL] [Abstract][Full Text] [Related]
4. Effects of amiodarone and posaconazole on the growth and ultrastructure of Trypanosoma cruzi.
Veiga-Santos P; Barrias ES; Santos JF; de Barros Moreira TL; de Carvalho TM; Urbina JA; de Souza W
Int J Antimicrob Agents; 2012 Jul; 40(1):61-71. PubMed ID: 22591838
[TBL] [Abstract][Full Text] [Related]
5. Comparative efficacies of TAK-187, a long-lasting ergosterol biosynthesis inhibitor, and benznidazole in preventing cardiac damage in a murine model of Chagas' disease.
Corrales M; Cardozo R; Segura MA; Urbina JA; Basombrío MA
Antimicrob Agents Chemother; 2005 Apr; 49(4):1556-60. PubMed ID: 15793138
[TBL] [Abstract][Full Text] [Related]
6. Development of Trypanosoma cruzi in vitro assays to identify compounds suitable for progression in Chagas' disease drug discovery.
MacLean LM; Thomas J; Lewis MD; Cotillo I; Gray DW; De Rycker M
PLoS Negl Trop Dis; 2018 Jul; 12(7):e0006612. PubMed ID: 30001347
[TBL] [Abstract][Full Text] [Related]
7. Match-making for posaconazole through systems thinking.
Fügi MA; Kaiser M; Tanner M; Schneiter R; Mäser P; Guan XL
Trends Parasitol; 2015 Feb; 31(2):46-51. PubMed ID: 25486978
[TBL] [Abstract][Full Text] [Related]
8. [The chemotherapy of Chagas disease].
Stoppani AO
Medicina (B Aires); 1999; 59 Suppl 2():147-65. PubMed ID: 10668258
[TBL] [Abstract][Full Text] [Related]
9. In vitro and in vivo antiparasital activity against Trypanosoma cruzi of three novel 5-methyl-1,2,4-triazolo[1,5-a]pyrimidin-7(4H)-one-based complexes.
Caballero AB; Marín C; Rodríguez-Diéguez A; Ramírez-Macías I; Barea E; Sánchez-Moreno M; Salas JM
J Inorg Biochem; 2011 Jun; 105(6):770-6. PubMed ID: 21497152
[TBL] [Abstract][Full Text] [Related]
10. Trypanocidal activity of ergosterol peroxide from Pleurotus ostreatus.
Ramos-Ligonio A; López-Monteon A; Trigos A
Phytother Res; 2012 Jun; 26(6):938-43. PubMed ID: 22083593
[TBL] [Abstract][Full Text] [Related]
11. Amiodarone inhibits Trypanosoma cruzi infection and promotes cardiac cell recovery with gap junction and cytoskeleton reassembly in vitro.
Adesse D; Azzam EM; Meirelles Mde N; Urbina JA; Garzoni LR
Antimicrob Agents Chemother; 2011 Jan; 55(1):203-10. PubMed ID: 21078932
[TBL] [Abstract][Full Text] [Related]
12. Limited Ability of Posaconazole To Cure both Acute and Chronic Trypanosoma cruzi Infections Revealed by Highly Sensitive In Vivo Imaging.
Francisco AF; Lewis MD; Jayawardhana S; Taylor MC; Chatelain E; Kelly JM
Antimicrob Agents Chemother; 2015 Aug; 59(8):4653-61. PubMed ID: 26014936
[TBL] [Abstract][Full Text] [Related]
13. Activity of "reversed" diamidines against Trypanosoma cruzi "in vitro".
Silva CF; Batista MM; Mota RA; de Souza EM; Stephens CE; Som P; Boykin DW; Soeiro Mde N
Biochem Pharmacol; 2007 Jun; 73(12):1939-46. PubMed ID: 17462605
[TBL] [Abstract][Full Text] [Related]
14. Ergosterol biosynthesis and drug development for Chagas disease.
Urbina JA
Mem Inst Oswaldo Cruz; 2009 Jul; 104 Suppl 1():311-8. PubMed ID: 19753490
[TBL] [Abstract][Full Text] [Related]
15. Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi.
Brand S; Ko EJ; Viayna E; Thompson S; Spinks D; Thomas M; Sandberg L; Francisco AF; Jayawardhana S; Smith VC; Jansen C; De Rycker M; Thomas J; MacLean L; Osuna-Cabello M; Riley J; Scullion P; Stojanovski L; Simeons FRC; Epemolu O; Shishikura Y; Crouch SD; Bakshi TS; Nixon CJ; Reid IH; Hill AP; Underwood TZ; Hindley SJ; Robinson SA; Kelly JM; Fiandor JM; Wyatt PG; Marco M; Miles TJ; Read KD; Gilbert IH
J Med Chem; 2017 Sep; 60(17):7284-7299. PubMed ID: 28844141
[TBL] [Abstract][Full Text] [Related]
16. Mevinolin (lovastatin) potentiates the antiproliferative effects of ketoconazole and terbinafine against Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies.
Urbina JA; Lazardi K; Marchan E; Visbal G; Aguirre T; Piras MM; Piras R; Maldonado RA; Payares G; de Souza W
Antimicrob Agents Chemother; 1993 Mar; 37(3):580-91. PubMed ID: 8460926
[TBL] [Abstract][Full Text] [Related]
17. Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi.
da Silva EN; Menna-Barreto RF; Pinto Mdo C; Silva RS; Teixeira DV; de Souza MC; De Simone CA; De Castro SL; Ferreira VF; Pinto AV
Eur J Med Chem; 2008 Aug; 43(8):1774-80. PubMed ID: 18045742
[TBL] [Abstract][Full Text] [Related]
18. Lipophilic antifolate trimetrexate is a potent inhibitor of Trypanosoma cruzi: prospect for chemotherapy of Chagas' disease.
Senkovich O; Bhatia V; Garg N; Chattopadhyay D
Antimicrob Agents Chemother; 2005 Aug; 49(8):3234-8. PubMed ID: 16048931
[TBL] [Abstract][Full Text] [Related]
19. The Anti-Trypanosoma cruzi activity of posaconazole in a murine model of acute Chagas' disease is less dependent on gamma interferon than that of benznidazole.
Ferraz ML; Gazzinelli RT; Alves RO; Urbina JA; Romanha AJ
Antimicrob Agents Chemother; 2007 Apr; 51(4):1359-64. PubMed ID: 17220408
[TBL] [Abstract][Full Text] [Related]
20. The Rationale for Use of Amiodarone and its Derivatives for the Treatment of Chagas' Disease and Leishmaniasis.
Benaim G; Paniz-Mondolfi AE; Sordillo EM
Curr Pharm Des; 2021; 27(15):1825-1833. PubMed ID: 32988342
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]