BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

231 related articles for article (PubMed ID: 16451082)

  • 1. Mono- and polynuclear [alkylamine]platinum(II) complexes of [1,2-bis(4-fluorophenyl)ethylenediamine]platinum(II): synthesis and investigations on cytotoxicity, cellular distribution, and DNA and protein binding.
    Kapp T; Dullin A; Gust R
    J Med Chem; 2006 Feb; 49(3):1182-90. PubMed ID: 16451082
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and cytotoxicity of enantiomerically pure [1,2-diamino-1-(4-fluorophenyl)-3-methylbutane]platinum(II) complexes.
    Dullin A; Dufrasne F; Gelbcke M; Gust R
    ChemMedChem; 2006 Jun; 1(6):644-53. PubMed ID: 16892405
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Platinum(II)-dendrimer conjugates: synthesis and investigations on cytotoxicity, cellular distribution, platinum release, DNA, and protein binding.
    Kapp T; Dullin A; Gust R
    Bioconjug Chem; 2010 Feb; 21(2):328-37. PubMed ID: 20104885
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dinuclear alkylamine platinum(II) complexes of [1,2-bis(4-fluorophenyl)ethylenediamine]platinum(II): influence of endocytosis and copper and organic cation transport systems on cellular uptake.
    Kapp T; Müller S; Gust R
    ChemMedChem; 2006 May; 1(5):560-4. PubMed ID: 16892392
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [N-ethyl- and [N,N'-diethyl-1,2-bis(2,6-difluoro-3-hydroxyphenyl)-ethylenediamine]dichloroplatinum(II): structure and cytotoxic/estrogenic activity in breast cancer cells.
    Gust R; Niebler K; Schönenberger H
    J Med Chem; 2005 Nov; 48(23):7132-44. PubMed ID: 16279771
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [1, 2-Bis(2, 6-difluoro-3-hydroxyphenyl)ethylene-diamine]platinum(II) complexes, compounds for the endocrine therapy of breast cancer - mode of action II: contribution of drug inactivation, cellular drug uptake and sterical factors in the drug-target interaction to the antitumor activity.
    Schertl S; Hartmann RW; Batzl-Hartmann C; Bernhardt G; Spruss T; Beckenlehner K; Koch M; Krauser R; Schlemmer R; Gust R; Schönenberger H
    Arch Pharm (Weinheim); 2004 Jun; 337(6):349-59. PubMed ID: 15188224
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and characterization of platinum(II) oxadiazoline complexes and their in vitro antitumor activity in platinum-sensitive and -resistant cancer cell lines.
    Coley HM; Sarju J; Wagner G
    J Med Chem; 2008 Jan; 51(1):135-41. PubMed ID: 18072719
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enantiomerically pure [1, 2-diamino-1-(4-fluorophenyl)butane]platinum(II) complexes: synthesis and antitumor activity against MCF-7 and MDA-MB 231 breast cancer and LnCaP/FGC prostate cancer cell lines.
    Dullin A; Dufrasne F; Gelbcke M; Gust R
    Arch Pharm (Weinheim); 2004 Dec; 337(12):654-67. PubMed ID: 15597399
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, cytotoxicity and DNA-binding levels of ammine/propylamine platinum(II) complexes with carboxylates.
    Zhang J; Zhao X
    Eur J Med Chem; 2007 Feb; 42(2):286-91. PubMed ID: 17084487
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and structure-activity relationship of novel antitumoral platinum xanthate complexes.
    Friebolin W; Schilling G; Zöller M; Amtmann E
    J Med Chem; 2004 Apr; 47(9):2256-63. PubMed ID: 15084124
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cytotoxic activities, cellular uptake, gene regulation, and optical imaging of novel platinum(II) complexes.
    Gao J; Liu YG; Zingaro RA
    Chem Res Toxicol; 2009 Oct; 22(10):1705-12. PubMed ID: 19694485
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Monofunctional platinum complexes showing potent cytotoxicity against human liver carcinoma cell line BEL-7402.
    Zhang J; Wang X; Tu C; Lin J; Ding J; Lin L; Wang Z; He C; Yan C; You X; Guo Z
    J Med Chem; 2003 Jul; 46(16):3502-7. PubMed ID: 12877588
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, DNA-binding affinity and cytotoxicity of the dinuclear platinum(II) complexes with berenil and amines ligands.
    Bielawski K; Bielawska A; Popławska B; Bołkun-Skórnicka U
    Acta Pol Pharm; 2008; 65(3):363-70. PubMed ID: 18646556
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and antitumor activity of enantiomerically pure [1,2-diamino-1-(4-fluorophenyl)propane]dichloroplatinum(II) complexes.
    Dufrasne F; Gelbcke M; Schnurr B; Gust R
    Arch Pharm (Weinheim); 2002 May; 335(5):229-39. PubMed ID: 12210780
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Studies of interaction of trichloro{eta2-cis-N,N-dimethyl-1-[6-(N',N'-dimethyl-ammoniummethyl)-cyclohex-3-ene-1-yl]-methylammonium}platinum(II) chloride with DNA: Effects on secondary and tertiary structures of DNA. Cytotoxic assays on human ovarian cancer cell lines, resistant and non-resistant to cisplatin.
    Gay M; Montaña AM; Moreno V; Prieto MJ; Pérez JM; Alonso C
    Bioorg Med Chem; 2006 Mar; 14(5):1565-72. PubMed ID: 16256352
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Platinum(II) compounds with chelating ligands based on pyridine and pyrimidine: synthesis, characterizations, DFT calculations, cytotoxic assays and binding to a DNA model base.
    Roy S; Westmaas JA; Buda F; Reedijk J
    J Inorg Biochem; 2009 Sep; 103(9):1278-87. PubMed ID: 19656572
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cellular accumulation and cytotoxicity of macromolecular platinum complexes in cisplatin-resistant tumor cells.
    Garmann D; Warnecke A; Kalayda GV; Kratz F; Jaehde U
    J Control Release; 2008 Oct; 131(2):100-6. PubMed ID: 18691617
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Platinum (II) complexes with stereochemically-defined thiepane dioxide diamine ligands as anticancer drugs.
    Cerè V; Grossi L; Munari D; Pollicino S; Martelli L; Martelli M
    Anticancer Res; 2006; 26(3A):1815-9. PubMed ID: 16827112
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytotoxicity of 2,2':6',2' '-terpyridineplatinum(II) complexes against human ovarian carcinoma.
    Lowe G; Droz AS; Vilaivan T; Weaver GW; Park JJ; Pratt JM; Tweedale L; Kelland LR
    J Med Chem; 1999 Aug; 42(16):3167-74. PubMed ID: 10447962
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biological effect of mono- and dinuclear alkylamine platinum(II) compounds on human lymphoma cells.
    Kapp T; Krueger M; Ott I; Steiner S; Schumacher P; Nachbaur D; Gastl G; Gust R; Kircher B
    J Inorg Biochem; 2008 Apr; 102(4):713-20. PubMed ID: 18078673
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.