120 related articles for article (PubMed ID: 1645192)
21. Fine structure-activity analysis of mutations at position 51 of tyrosyl-tRNA synthetase.
Fersht AR; Wilkinson AJ; Carter P; Winter G
Biochemistry; 1985 Oct; 24(21):5858-61. PubMed ID: 3002425
[TBL] [Abstract][Full Text] [Related]
22. Crystal structure of tryptophanyl-tRNA synthetase complexed with adenosine-5' tetraphosphate: evidence for distributed use of catalytic binding energy in amino acid activation by class I aminoacyl-tRNA synthetases.
Retailleau P; Weinreb V; Hu M; Carter CW
J Mol Biol; 2007 May; 369(1):108-28. PubMed ID: 17428498
[TBL] [Abstract][Full Text] [Related]
23. Analysis of the role of the KMSKS loop in the catalytic mechanism of the tyrosyl-tRNA synthetase using multimutant cycles.
First EA; Fersht AR
Biochemistry; 1995 Apr; 34(15):5030-43. PubMed ID: 7711024
[TBL] [Abstract][Full Text] [Related]
24. Natural variation of tyrosyl-tRNA synthetase and comparison with engineered mutants.
Jones MD; Lowe DM; Borgford T; Fersht AR
Biochemistry; 1986 Apr; 25(8):1887-91. PubMed ID: 3011073
[TBL] [Abstract][Full Text] [Related]
25. Use of binding energy in catalysis analyzed by mutagenesis of the tyrosyl-tRNA synthetase.
Wells TN; Fersht AR
Biochemistry; 1986 Apr; 25(8):1881-6. PubMed ID: 3518794
[TBL] [Abstract][Full Text] [Related]
26. Protection of an unstable reaction intermediate examined with linear free energy relationships in tyrosyl-tRNA synthetase.
Wells TN; Fersht AR
Biochemistry; 1989 Nov; 28(23):9201-9. PubMed ID: 2690955
[TBL] [Abstract][Full Text] [Related]
27. Site-directed mutagenesis as a probe of enzyme structure and catalysis: tyrosyl-tRNA synthetase cysteine-35 to glycine-35 mutation.
Wilkinson AJ; Fersht AR; Blow DM; Winter G
Biochemistry; 1983 Jul; 22(15):3581-6. PubMed ID: 6615786
[TBL] [Abstract][Full Text] [Related]
28. The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus).
Carter PJ; Winter G; Wilkinson AJ; Fersht AR
Cell; 1984 Oct; 38(3):835-40. PubMed ID: 6488318
[TBL] [Abstract][Full Text] [Related]
29. Modification of the amino acid specificity of tyrosyl-tRNA synthetase by protein engineering.
de Prat Gay G; Duckworth HW; Fersht AR
FEBS Lett; 1993 Mar; 318(2):167-71. PubMed ID: 8440372
[TBL] [Abstract][Full Text] [Related]
30. Asymmetry of tyrosyl-tRNA synthetase in solution.
Ward WH; Fersht AR
Biochemistry; 1988 Feb; 27(3):1041-9. PubMed ID: 3365365
[TBL] [Abstract][Full Text] [Related]
31. Structure-activity relationships in engineered proteins: characterization of disruptive deletions in the alpha-ammonium group binding site of tyrosyl-tRNA synthetase.
Lowe DM; Winter G; Fersht AR
Biochemistry; 1987 Sep; 26(19):6038-43. PubMed ID: 3480006
[TBL] [Abstract][Full Text] [Related]
32. Potassium functionally replaces the second lysine of the KMSKS signature sequence in human tyrosyl-tRNA synthetase.
Austin J; First EA
J Biol Chem; 2002 Jun; 277(23):20243-8. PubMed ID: 11927599
[TBL] [Abstract][Full Text] [Related]
33. Site-directed mutagenesis reveals transition-state stabilization as a general catalytic mechanism for aminoacyl-tRNA synthetases.
Borgford TJ; Gray TE; Brand NJ; Fersht AR
Biochemistry; 1987 Nov; 26(23):7246-50. PubMed ID: 3427072
[TBL] [Abstract][Full Text] [Related]
34. Mechanism of aminoacylation of tRNA. Proof of the aminoacyl adenylate pathway for the isoleucyl- and tyrosyl-tRNA synthetases from Escherichia coli K12.
Fersht AR; Kaethner MM
Biochemistry; 1976 Feb; 15(4):818-23. PubMed ID: 764868
[TBL] [Abstract][Full Text] [Related]
35. Protein engineering of homodimeric tyrosyl-tRNA synthetase to produce active heterodimers.
Ward WH; Jones DH; Fersht AR
J Biol Chem; 1986 Jul; 261(21):9576-8. PubMed ID: 3733687
[TBL] [Abstract][Full Text] [Related]
36. Spectrophotometric assays for monitoring tRNA aminoacylation and aminoacyl-tRNA hydrolysis reactions.
First EA; Richardson CJ
Methods; 2017 Jan; 113():3-12. PubMed ID: 27780756
[TBL] [Abstract][Full Text] [Related]
37. Metal ion dependence of phosphorothioate ATP analogues in the Bacillus stearothermophilus tyrosyl-tRNA synthetase reaction.
Garcia GA; Leatherbarrow RJ; Eckstein F; Fersht AR
Biochemistry; 1990 Feb; 29(6):1643-8. PubMed ID: 2334722
[TBL] [Abstract][Full Text] [Related]
38. Reconstruction by site-directed mutagenesis of the transition state for the activation of tyrosine by the tyrosyl-tRNA synthetase: a mobile loop envelopes the transition state in an induced-fit mechanism.
Fersht AR; Knill-Jones JW; Bedouelle H; Winter G
Biochemistry; 1988 Mar; 27(5):1581-7. PubMed ID: 3284584
[TBL] [Abstract][Full Text] [Related]
39. Dissection of the structure and activity of the tyrosyl-tRNA synthetase by site-directed mutagenesis.
Fersht AR
Biochemistry; 1987 Dec; 26(25):8031-7. PubMed ID: 3442641
[TBL] [Abstract][Full Text] [Related]
40. Investigation of transition-state stabilization by residues histidine-45 and threonine-40 in the tyrosyl-tRNA synthetase.
Leatherbarrow RJ; Fersht AR
Biochemistry; 1987 Dec; 26(26):8524-8. PubMed ID: 3126804
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
