262 related articles for article (PubMed ID: 16454525)
1. Regulation of recombinant monoclonal antibody production in chinese hamster ovary cells: a comparative study of gene copy number, mRNA level, and protein expression.
Jiang Z; Huang Y; Sharfstein ST
Biotechnol Prog; 2006; 22(1):313-8. PubMed ID: 16454525
[TBL] [Abstract][Full Text] [Related]
2. A study of monoclonal antibody-producing CHO cell lines: what makes a stable high producer?
Chusainow J; Yang YS; Yeo JH; Toh PC; Asvadi P; Wong NS; Yap MG
Biotechnol Bioeng; 2009 Mar; 102(4):1182-96. PubMed ID: 18979540
[TBL] [Abstract][Full Text] [Related]
3. On the optimal ratio of heavy to light chain genes for efficient recombinant antibody production by CHO cells.
Schlatter S; Stansfield SH; Dinnis DM; Racher AJ; Birch JR; James DC
Biotechnol Prog; 2005; 21(1):122-33. PubMed ID: 15903249
[TBL] [Abstract][Full Text] [Related]
4. Clonal variability within dihydrofolate reductase-mediated gene amplified Chinese hamster ovary cells: stability in the absence of selective pressure.
Kim NS; Kim SJ; Lee GM
Biotechnol Bioeng; 1998 Dec; 60(6):679-88. PubMed ID: 10099478
[TBL] [Abstract][Full Text] [Related]
5. The absence of effect of gene copy number and mRNA level on the amount of mAb secretion from mammalian cells.
Reisinger H; Steinfellner W; Stern B; Katinger H; Kunert R
Appl Microbiol Biotechnol; 2008 Dec; 81(4):701-10. PubMed ID: 18810429
[TBL] [Abstract][Full Text] [Related]
6. Key determinants in the occurrence of clonal variation in humanized antibody expression of cho cells during dihydrofolate reductase mediated gene amplification.
Kim NS; Byun TH; Lee GM
Biotechnol Prog; 2001; 17(1):69-75. PubMed ID: 11170482
[TBL] [Abstract][Full Text] [Related]
7. Characterization of chimeric antibody producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure.
Kim SJ; Kim NS; Ryu CJ; Hong HJ; Lee GM
Biotechnol Bioeng; 1998 Apr; 58(1):73-84. PubMed ID: 10099263
[TBL] [Abstract][Full Text] [Related]
8. Cell line-specific control of recombinant monoclonal antibody production by CHO cells.
O'Callaghan PM; McLeod J; Pybus LP; Lovelady CS; Wilkinson SJ; Racher AJ; Porter A; James DC
Biotechnol Bioeng; 2010 Aug; 106(6):938-51. PubMed ID: 20589672
[TBL] [Abstract][Full Text] [Related]
9. Sodium butyrate stimulates monoclonal antibody over-expression in CHO cells by improving gene accessibility.
Jiang Z; Sharfstein ST
Biotechnol Bioeng; 2008 May; 100(1):189-94. PubMed ID: 18023047
[TBL] [Abstract][Full Text] [Related]
10. Adaptation of Chinese hamster ovary cells to low culture temperature: cell growth and recombinant protein production.
Yoon SK; Hong JK; Choo SH; Song JY; Park HW; Lee GM
J Biotechnol; 2006 Apr; 122(4):463-72. PubMed ID: 16253368
[TBL] [Abstract][Full Text] [Related]
11. Comparison of expression of a humanized monoclonal antibody in mouse NSO myeloma cells and Chinese hamster ovary cells.
Peakman TC; Worden J; Harris RH; Cooper H; Tite J; Page MJ; Gewert DR; Bartholemew M; Crowe JS; Brett S
Hum Antibodies Hybridomas; 1994; 5(1-2):65-74. PubMed ID: 7532024
[TBL] [Abstract][Full Text] [Related]
12. Auditioning of CHO host cell lines using the artificial chromosome expression (ACE) technology.
Kennard ML; Goosney DL; Monteith D; Roe S; Fischer D; Mott J
Biotechnol Bioeng; 2009 Oct; 104(3):526-39. PubMed ID: 19544304
[TBL] [Abstract][Full Text] [Related]
13. Impact of gene vector design on the control of recombinant monoclonal antibody production by Chinese hamster ovary cells.
Davies SL; O'Callaghan PM; McLeod J; Pybus LP; Sung YH; Rance J; Wilkinson SJ; Racher AJ; Young RJ; James DC
Biotechnol Prog; 2011; 27(6):1689-99. PubMed ID: 21882365
[TBL] [Abstract][Full Text] [Related]
14. Control of culture environment for improved polyethylenimine-mediated transient production of recombinant monoclonal antibodies by CHO cells.
Galbraith DJ; Tait AS; Racher AJ; Birch JR; James DC
Biotechnol Prog; 2006; 22(3):753-62. PubMed ID: 16739959
[TBL] [Abstract][Full Text] [Related]
15. Effects of cloned gene dosage on the response of recombinant CHO cells to hyperosmotic pressure in regard to cell growth and antibody production.
Ryu JS; Lee MS; Lee GM
Biotechnol Prog; 2001; 17(6):993-9. PubMed ID: 11735431
[TBL] [Abstract][Full Text] [Related]
16. mRNA stability and antibody production in CHO cells: improvement through gene optimization.
Hung F; Deng L; Ravnikar P; Condon R; Li B; Do L; Saha D; Tsao YS; Merchant A; Liu Z; Shi S
Biotechnol J; 2010 Apr; 5(4):393-401. PubMed ID: 20222103
[TBL] [Abstract][Full Text] [Related]
17. Enhancing effect of low culture temperature on specific antibody productivity of recombinant Chinese hamster ovary cells: clonal variation.
Yoon SK; Hwang SO; Lee GM
Biotechnol Prog; 2004; 20(6):1683-8. PubMed ID: 15575699
[TBL] [Abstract][Full Text] [Related]
18. Cytogenetic analysis of chimeric antibody-producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure.
Kim SJ; Lee GM
Biotechnol Bioeng; 1999 Sep; 64(6):741-9. PubMed ID: 10417224
[TBL] [Abstract][Full Text] [Related]
19. A clone screening method using mRNA levels to determine specific productivity and product quality for monoclonal antibodies.
Lee CJ; Seth G; Tsukuda J; Hamilton RW
Biotechnol Bioeng; 2009 Mar; 102(4):1107-18. PubMed ID: 18985612
[TBL] [Abstract][Full Text] [Related]
20. Characterisation of recombinant CHO cell lines by investigation of protein productivities and genetic parameters.
Lattenmayer C; Trummer E; Schriebl K; Vorauer-Uhl K; Mueller D; Katinger H; Kunert R
J Biotechnol; 2007 Mar; 128(4):716-25. PubMed ID: 17324483
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
