BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 16458512)

  • 1. Specific inhibitors of Plasmodium falciparum thioredoxin reductase as potential antimalarial agents.
    Andricopulo AD; Akoachere MB; Krogh R; Nickel C; McLeish MJ; Kenyon GL; Arscott LD; Williams CH; Davioud-Charvet E; Becker K
    Bioorg Med Chem Lett; 2006 Apr; 16(8):2283-92. PubMed ID: 16458512
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism-based inactivation of thioredoxin reductase from Plasmodium falciparum by Mannich bases. Implication for cytotoxicity.
    Davioud-Charvet E; McLeish MJ; Veine DM; Giegel D; Arscott LD; Andricopulo AD; Becker K; Müller S; Schirmer RH; Williams CH; Kenyon GL
    Biochemistry; 2003 Nov; 42(45):13319-30. PubMed ID: 14609342
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thioredoxin reductase from Plasmodium falciparum: evidence for interaction between the C-terminal cysteine residues and the active site disulfide-dithiol.
    Wang PF; Arscott LD; Gilberger TW; Müller S; Williams CH
    Biochemistry; 1999 Mar; 38(10):3187-96. PubMed ID: 10074374
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Preliminary LC-MS Based Screening for Inhibitors of Plasmodium falciparum Thioredoxin Reductase (PfTrxR) among a Set of Antimalarials from the Malaria Box.
    Tiwari NK; Reynolds PJ; Calderón AI
    Molecules; 2016 Mar; 21(4):424. PubMed ID: 27043496
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of liquid chromatography/mass spectrometry based screening assay for PfTrxR inhibitors using relative quantitation of intact thioredoxin.
    Munigunti R; Calderón AI
    Rapid Commun Mass Spectrom; 2012 Sep; 26(17):2051-6. PubMed ID: 22847705
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of the Plasmodium falciparum thioredoxin reductase-thioredoxin complex.
    Fritz-Wolf K; Jortzik E; Stumpf M; Preuss J; Iozef R; Rahlfs S; Becker K
    J Mol Biol; 2013 Sep; 425(18):3446-60. PubMed ID: 23845423
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery and biochemical characterization of Plasmodium thioredoxin reductase inhibitors from an antimalarial set.
    Theobald AJ; Caballero I; Coma I; Colmenarejo G; Cid C; Gamo FJ; Hibbs MJ; Bass AL; Thomas DA
    Biochemistry; 2012 Jun; 51(23):4764-71. PubMed ID: 22612231
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of oleamide in Guatteria recurvisepala by LC/MS-based Plasmodium falciparum thioredoxin reductase ligand binding method.
    Munigunti R; Nelson N; Mulabagal V; Gupta MP; Brun R; Calderón AI
    Planta Med; 2011 Oct; 77(15):1749-53. PubMed ID: 21567357
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Determination of antiplasmodial activity and binding affinity of curcumin and demethoxycurcumin towards PfTrxR.
    Munigunti R; Gathiaka S; Acevedo O; Sahu R; Tekwani B; Calderón AI
    Nat Prod Res; 2014; 28(6):359-64. PubMed ID: 24443991
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential inhibition of high and low Mr thioredoxin reductases of parasites by organotelluriums supports the concept that low Mr thioredoxin reductases are good drug targets.
    McMillan PJ; Patzewitz EM; Young SE; Westrop GD; Coombs GH; Engman L; Müller S
    Parasitology; 2009 Jan; 136(1):27-33. PubMed ID: 18980703
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Double-drug development against antioxidant enzymes from Plasmodium falciparum.
    Biot C; Dessolin J; Grellier P; Davioud-Charvet E
    Redox Rep; 2003; 8(5):280-3. PubMed ID: 14962365
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystal structure of Plasmodium falciparum thioredoxin reductase, a validated drug target.
    Boumis G; Giardina G; Angelucci F; Bellelli A; Brunori M; Dimastrogiovanni D; Saccoccia F; Miele AE
    Biochem Biophys Res Commun; 2012 Sep; 425(4):806-11. PubMed ID: 22889878
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Plasmodium falciparum Thioredoxin Reductase (PfTrxR) and Its Role as a Target for New Antimalarial Discovery.
    McCarty SE; Schellenberger A; Goodwin DC; Fuanta NR; Tekwani BL; Calderón AI
    Molecules; 2015 Jun; 20(6):11459-73. PubMed ID: 26111176
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of 5,5'-dithiobis(2-nitrobenzamides) as alternative substrates for trypanothione reductase and thioredoxin reductase: a microtiter colorimetric assay for inhibitor screening.
    Davioud-Charvet E; Becker K; Landry V; Gromer S; Logé C; Sergheraert C
    Anal Biochem; 1999 Mar; 268(1):1-8. PubMed ID: 10036154
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of Mammalian thioredoxin reductase by some flavonoids: implications for myricetin and quercetin anticancer activity.
    Lu J; Papp LV; Fang J; Rodriguez-Nieto S; Zhivotovsky B; Holmgren A
    Cancer Res; 2006 Apr; 66(8):4410-8. PubMed ID: 16618767
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Screening of natural compounds for ligands to PfTrxR by ultrafiltration and LC-MS based binding assay.
    Munigunti R; Mulabagal V; Calderón AI
    J Pharm Biomed Anal; 2011 May; 55(2):265-71. PubMed ID: 21353756
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The relationship of the redox potentials of thioredoxin and thioredoxin reductase from Drosophila melanogaster to the enzymatic mechanism: reduced thioredoxin is the reductant of glutathione in Drosophila.
    Cheng Z; Arscott LD; Ballou DP; Williams CH
    Biochemistry; 2007 Jul; 46(26):7875-85. PubMed ID: 17550271
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ebselen: a substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant.
    Zhao R; Masayasu H; Holmgren A
    Proc Natl Acad Sci U S A; 2002 Jun; 99(13):8579-84. PubMed ID: 12070343
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antimalarial dual drugs based on potent inhibitors of glutathione reductase from Plasmodium falciparum.
    Friebolin W; Jannack B; Wenzel N; Furrer J; Oeser T; Sanchez CP; Lanzer M; Yardley V; Becker K; Davioud-Charvet E
    J Med Chem; 2008 Mar; 51(5):1260-77. PubMed ID: 18260613
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural model of the Plasmodium falciparum thioredoxin reductase:a novel target for antimalarial drugs.
    Banerjee AK; Arora N; Murty US
    J Vector Borne Dis; 2009 Sep; 46(3):171-83. PubMed ID: 19724080
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.