These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

873 related articles for article (PubMed ID: 16461887)

  • 1. Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody.
    McClintock D; Gordon LB; Djabali K
    Proc Natl Acad Sci U S A; 2006 Feb; 103(7):2154-9. PubMed ID: 16461887
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition.
    Glynn MW; Glover TW
    Hum Mol Genet; 2005 Oct; 14(20):2959-69. PubMed ID: 16126733
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dermal fibroblasts in Hutchinson-Gilford progeria syndrome with the lamin A G608G mutation have dysmorphic nuclei and are hypersensitive to heat stress.
    Paradisi M; McClintock D; Boguslavsky RL; Pedicelli C; Worman HJ; Djabali K
    BMC Cell Biol; 2005 Jun; 6():27. PubMed ID: 15982412
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of mitochondrial dysfunction in Hutchinson-Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture.
    Rivera-Torres J; Acín-Perez R; Cabezas-Sánchez P; Osorio FG; Gonzalez-Gómez C; Megias D; Cámara C; López-Otín C; Enríquez JA; Luque-García JL; Andrés V
    J Proteomics; 2013 Oct; 91():466-77. PubMed ID: 23969228
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome.
    Capell BC; Erdos MR; Madigan JP; Fiordalisi JJ; Varga R; Conneely KN; Gordon LB; Der CJ; Cox AD; Collins FS
    Proc Natl Acad Sci U S A; 2005 Sep; 102(36):12879-84. PubMed ID: 16129833
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Progerin impairs chromosome maintenance by depleting CENP-F from metaphase kinetochores in Hutchinson-Gilford progeria fibroblasts.
    Eisch V; Lu X; Gabriel D; Djabali K
    Oncotarget; 2016 Apr; 7(17):24700-18. PubMed ID: 27015553
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford progeria syndrome cells.
    Mehta IS; Eskiw CH; Arican HD; Kill IR; Bridger JM
    Genome Biol; 2011 Aug; 12(8):R74. PubMed ID: 21838864
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Defective lamin A-Rb signaling in Hutchinson-Gilford Progeria Syndrome and reversal by farnesyltransferase inhibition.
    Marji J; O'Donoghue SI; McClintock D; Satagopam VP; Schneider R; Ratner D; Worman HJ; Gordon LB; Djabali K
    PLoS One; 2010 Jun; 5(6):e11132. PubMed ID: 20559568
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sulforaphane enhances progerin clearance in Hutchinson-Gilford progeria fibroblasts.
    Gabriel D; Roedl D; Gordon LB; Djabali K
    Aging Cell; 2015 Feb; 14(1):78-91. PubMed ID: 25510262
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Vitamin D receptor signaling improves Hutchinson-Gilford progeria syndrome cellular phenotypes.
    Kreienkamp R; Croke M; Neumann MA; Bedia-Diaz G; Graziano S; Dusso A; Dorsett D; Carlberg C; Gonzalo S
    Oncotarget; 2016 May; 7(21):30018-31. PubMed ID: 27145372
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson-Gilford progeria syndrome mutation.
    Yang SH; Bergo MO; Toth JI; Qiao X; Hu Y; Sandoval S; Meta M; Bendale P; Gelb MH; Young SG; Fong LG
    Proc Natl Acad Sci U S A; 2005 Jul; 102(29):10291-6. PubMed ID: 16014412
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cellular stress and AMPK activation as a common mechanism of action linking the effects of metformin and diverse compounds that alleviate accelerated aging defects in Hutchinson-Gilford progeria syndrome.
    Finley J
    Med Hypotheses; 2018 Sep; 118():151-162. PubMed ID: 30037605
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Epigenetic involvement in Hutchinson-Gilford progeria syndrome: a mini-review.
    Arancio W; Pizzolanti G; Genovese SI; Pitrone M; Giordano C
    Gerontology; 2014; 60(3):197-203. PubMed ID: 24603298
    [TBL] [Abstract][Full Text] [Related]  

  • 14. All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype.
    Pellegrini C; Columbaro M; Capanni C; D'Apice MR; Cavallo C; Murdocca M; Lattanzi G; Squarzoni S
    Oncotarget; 2015 Oct; 6(30):29914-28. PubMed ID: 26359359
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hutchinson-Gilford progeria syndrome through the lens of transcription.
    Prokocimer M; Barkan R; Gruenbaum Y
    Aging Cell; 2013 Aug; 12(4):533-43. PubMed ID: 23496208
    [TBL] [Abstract][Full Text] [Related]  

  • 16. LMNA-associated cardiocutaneous progeria: an inherited autosomal dominant premature aging syndrome with late onset.
    Kane MS; Lindsay ME; Judge DP; Barrowman J; Ap Rhys C; Simonson L; Dietz HC; Michaelis S
    Am J Med Genet A; 2013 Jul; 161A(7):1599-611. PubMed ID: 23666920
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rescue of heterochromatin organization in Hutchinson-Gilford progeria by drug treatment.
    Columbaro M; Capanni C; Mattioli E; Novelli G; Parnaik VK; Squarzoni S; Maraldi NM; Lattanzi G
    Cell Mol Life Sci; 2005 Nov; 62(22):2669-78. PubMed ID: 16261260
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Presence and distribution of progerin in HGPS cells is ameliorated by drugs that impact on the mevalonate and mTOR pathways.
    Clements CS; Bikkul MU; Ofosu W; Eskiw C; Tree D; Makarov E; Kill IR; Bridger JM
    Biogerontology; 2019 Jun; 20(3):337-358. PubMed ID: 31041622
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin.
    McClintock D; Ratner D; Lokuge M; Owens DM; Gordon LB; Collins FS; Djabali K
    PLoS One; 2007 Dec; 2(12):e1269. PubMed ID: 18060063
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Status of treatment strategies for Hutchinson-Gilford progeria syndrome with a focus on prelamin: A posttranslational modification.
    Chen X; Yao H; Andrés V; Bergo MO; Kashif M
    Basic Clin Pharmacol Toxicol; 2022 Oct; 131(4):217-223. PubMed ID: 35790078
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 44.