194 related articles for article (PubMed ID: 16464479)
1. Phenacetin acts as a weak genotoxic compound preferentially in the kidney of DNA repair deficient Xpa mice.
Luijten M; Speksnijder EN; van Alphen N; Westerman A; Heisterkamp SH; van Benthem J; van Kreijl CF; Beems RB; van Steeg H
Mutat Res; 2006 Apr; 596(1-2):143-50. PubMed ID: 16464479
[TBL] [Abstract][Full Text] [Related]
2. Effect of heterozygous loss of p53 on benzo[a]pyrene-induced mutations and tumors in DNA repair-deficient XPA mice.
van Oostrom CT; Boeve M; van Den Berg J; de Vries A; Dollé ME; Beems RB; van Kreijl CF; Vijg J; van Steeg H
Environ Mol Mutagen; 1999; 34(2-3):124-30. PubMed ID: 10529736
[TBL] [Abstract][Full Text] [Related]
3. p53 heterozygosity results in an increased 2-acetylaminofluorene-induced urinary bladder but not liver tumor response in DNA repair-deficient Xpa mice.
Hoogervorst EM; van Oostrom CT; Beems RB; van Benthem J; Gielis S; Vermeulen JP; Wester PW; Vos JG; de Vries A; van Steeg H
Cancer Res; 2004 Aug; 64(15):5118-26. PubMed ID: 15289314
[TBL] [Abstract][Full Text] [Related]
4. Finding transcriptomics biomarkers for in vivo identification of (non-)genotoxic carcinogens using wild-type and Xpa/p53 mutant mouse models.
Jonker MJ; Bruning O; van Iterson M; Schaap MM; van der Hoeven TV; Vrieling H; Beems RB; de Vries A; van Steeg H; Breit TM; Luijten M
Carcinogenesis; 2009 Oct; 30(10):1805-12. PubMed ID: 19696161
[TBL] [Abstract][Full Text] [Related]
5. Evaluation of the Xpa-deficient transgenic mouse model for short-term carcinogenicity testing: 9-month studies with haloperidol, reserpine, phenacetin, and D-mannitol.
Lina BA; Woutersen RA; Bruijntjes JP; van Benthem J; van den Berg JA; Monbaliu J; Thoolen BJ; Beems RB; van Kreijl CF
Toxicol Pathol; 2004; 32(2):192-201. PubMed ID: 15200157
[TBL] [Abstract][Full Text] [Related]
6. Mutation spectrum in UVB-exposed skin epidermis of Xpa-knockout mice: frequent recovery of triplet mutations.
Ikehata H; Yanase F; Mori T; Nikaido O; Tanaka K; Ono T
Environ Mol Mutagen; 2007 Jan; 48(1):1-13. PubMed ID: 17163503
[TBL] [Abstract][Full Text] [Related]
7. Deregulation of cancer-related pathways in primary hepatocytes derived from DNA repair-deficient Xpa-/-p53+/- mice upon exposure to benzo[a]pyrene.
van Kesteren PC; Zwart PE; Pennings JL; Gottschalk WH; Kleinjans JC; van Delft JH; van Steeg H; Luijten M
Toxicol Sci; 2011 Sep; 123(1):123-32. PubMed ID: 21715664
[TBL] [Abstract][Full Text] [Related]
8. Detection of genotoxic and non-genotoxic carcinogens in Xpc(-/-)p53(+/-) mice.
Melis JP; Speksnijder EN; Kuiper RV; Salvatori DC; Schaap MM; Maas S; Robinson J; Verhoef A; van Benthem J; Luijten M; van Steeg H
Toxicol Appl Pharmacol; 2013 Jan; 266(2):289-97. PubMed ID: 23153559
[TBL] [Abstract][Full Text] [Related]
9. Role of nucleotide excision repair deficiency in intestinal tumorigenesis in multiple intestinal neoplasia (Min) mice.
Steffensen IL; Schut HA; Nesland JM; Tanaka K; Alexander J
Mutat Res; 2006 Dec; 611(1-2):71-82. PubMed ID: 16962818
[TBL] [Abstract][Full Text] [Related]
10. Accelerated accumulation of somatic mutations in mice deficient in the nucleotide excision repair gene XPA.
Giese H; Dollé ME; Hezel A; van Steeg H; Vijg J
Oncogene; 1999 Feb; 18(5):1257-60. PubMed ID: 10022133
[TBL] [Abstract][Full Text] [Related]
11. Mouse models for xeroderma pigmentosum group A and group C show divergent cancer phenotypes.
Melis JP; Wijnhoven SW; Beems RB; Roodbergen M; van den Berg J; Moon H; Friedberg E; van der Horst GT; Hoeijmakers JH; Vijg J; van Steeg H
Cancer Res; 2008 Mar; 68(5):1347-53. PubMed ID: 18316597
[TBL] [Abstract][Full Text] [Related]
12. The relationship between benzo[a]pyrene-induced mutagenesis and carcinogenesis in repair-deficient Cockayne syndrome group B mice.
Wijnhoven SW; Kool HJ; van Oostrom CT; Beems RB; Mullenders LH; van Zeeland AA; van der Horst GT; Vrieling H; van Steeg H
Cancer Res; 2000 Oct; 60(20):5681-7. PubMed ID: 11059760
[TBL] [Abstract][Full Text] [Related]
13. Elevated frequencies of benzo(a)pyrene-induced Hprt mutations in internal tissue of XPA-deficient mice.
Bol SA; van Steeg H; Jansen JG; Van Oostrom C; de Vries A; de Groot AJ; Tates AD; Vrieling H; van Zeeland AA; Mullenders LH
Cancer Res; 1998 Jul; 58(13):2850-6. PubMed ID: 9661901
[TBL] [Abstract][Full Text] [Related]
14. Cell-type-specific consequences of nucleotide excision repair deficiencies: Embryonic stem cells versus fibroblasts.
de Waard H; Sonneveld E; de Wit J; Esveldt-van Lange R; Hoeijmakers JH; Vrieling H; van der Horst GT
DNA Repair (Amst); 2008 Oct; 7(10):1659-69. PubMed ID: 18634906
[TBL] [Abstract][Full Text] [Related]
15. DNA repair-deficient Xpa and Xpa/p53+/- knock-out mice: nature of the models.
van Steeg H; de Vries A; van Oostrom CTh ; van Benthem J; Beems RB; van Kreijl CF
Toxicol Pathol; 2001; 29 Suppl():109-16. PubMed ID: 11695546
[TBL] [Abstract][Full Text] [Related]
16. Relationship between UV-induced mutant p53 patches and skin tumours, analysed by mutation spectra and by induction kinetics in various DNA-repair-deficient mice.
Rebel H; Kram N; Westerman A; Banus S; van Kranen HJ; de Gruijl FR
Carcinogenesis; 2005 Dec; 26(12):2123-30. PubMed ID: 16051635
[TBL] [Abstract][Full Text] [Related]
17. Mice deficient in the nucleotide excision repair gene XPA have elevated sensitivity to benzo[a]pyrene induction of lung tumors.
Ide F; Iida N; Nakatsuru Y; Oda H; Tanaka K; Ishikawa T
Carcinogenesis; 2000 Jun; 21(6):1263-5. PubMed ID: 10837020
[TBL] [Abstract][Full Text] [Related]
18. DNA repair-deficient Xpa/p53 knockout mice are sensitive to the non-genotoxic carcinogen cyclosporine A: escape of initiated cells from immunosurveillance?
van Kesteren PC; Beems RB; Luijten M; Robinson J; de Vries A; van Steeg H
Carcinogenesis; 2009 Mar; 30(3):538-43. PubMed ID: 19136475
[TBL] [Abstract][Full Text] [Related]
19. Spontaneous liver tumors and benzo[a]pyrene-induced lymphomas in XPA-deficient mice.
de Vries A; van Oostrom CT; Dortant PM; Beems RB; van Kreijl CF; Capel PJ; van Steeg H
Mol Carcinog; 1997 May; 19(1):46-53. PubMed ID: 9180928
[TBL] [Abstract][Full Text] [Related]
20. XPA-deficiency in hairless mice causes a shift in skin tumor types and mutational target genes after exposure to low doses of U.V.B.
de Vries A; Berg RJ; Wijnhoven S; Westerman A; Wester PW; van Kreijl CF; Capel PJ; de Gruijl FR; van Kranen HJ; van Steeg H
Oncogene; 1998 Apr; 16(17):2205-12. PubMed ID: 9619829
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]