BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

237 related articles for article (PubMed ID: 16467077)

  • 1. Handicapping the race to develop inhibitors of the phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway.
    Granville CA; Memmott RM; Gills JJ; Dennis PA
    Clin Cancer Res; 2006 Feb; 12(3 Pt 1):679-89. PubMed ID: 16467077
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting Akt in cancer therapy.
    LoPiccolo J; Granville CA; Gills JJ; Dennis PA
    Anticancer Drugs; 2007 Sep; 18(8):861-74. PubMed ID: 17667591
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting the PI3K/AKT/mTOR signaling network in acute myelogenous leukemia.
    Martelli AM; Evangelisti C; Chiarini F; Grimaldi C; Manzoli L; McCubrey JA
    Expert Opin Investig Drugs; 2009 Sep; 18(9):1333-49. PubMed ID: 19678801
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Noradrenaline enhances the expression of the neuronal monocarboxylate transporter MCT2 by translational activation via stimulation of PI3K/Akt and the mTOR/S6K pathway.
    Chenal J; Pellerin L
    J Neurochem; 2007 Jul; 102(2):389-97. PubMed ID: 17394554
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins.
    Xu Y; Chen SY; Ross KN; Balk SP
    Cancer Res; 2006 Aug; 66(15):7783-92. PubMed ID: 16885382
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphatidylinositol-3-kinase/Akt signaling pathway and kidney cancer, and the therapeutic potential of phosphatidylinositol-3-kinase/Akt inhibitors.
    Porta C; Figlin RA
    J Urol; 2009 Dec; 182(6):2569-77. PubMed ID: 19836781
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting the PI3K-AKT-mTOR pathway: progress, pitfalls, and promises.
    Yap TA; Garrett MD; Walton MI; Raynaud F; de Bono JS; Workman P
    Curr Opin Pharmacol; 2008 Aug; 8(4):393-412. PubMed ID: 18721898
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antimyeloma activity of the orally bioavailable dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235.
    McMillin DW; Ooi M; Delmore J; Negri J; Hayden P; Mitsiades N; Jakubikova J; Maira SM; Garcia-Echeverria C; Schlossman R; Munshi NC; Richardson PG; Anderson KC; Mitsiades CS
    Cancer Res; 2009 Jul; 69(14):5835-42. PubMed ID: 19584292
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of class I phosphoinositide 3-kinase activity impairs proliferation and triggers apoptosis in acute promyelocytic leukemia without affecting atra-induced differentiation.
    Billottet C; Banerjee L; Vanhaesebroeck B; Khwaja A
    Cancer Res; 2009 Feb; 69(3):1027-36. PubMed ID: 19176369
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting mTOR signaling in lung cancer.
    Marinov M; Fischer B; Arcaro A
    Crit Rev Oncol Hematol; 2007 Aug; 63(2):172-82. PubMed ID: 17540577
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A role for Akt in epidermal growth factor-stimulated cell cycle progression in cultured hepatocytes: generation of a hyperproliferative window after adenoviral expression of constitutively active Akt.
    Luo Y; Dixon CJ; Hall JF; White PJ; Boarder MR
    J Pharmacol Exp Ther; 2007 Jun; 321(3):884-91. PubMed ID: 17371807
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Down-regulation of phosphatidylinositol 3'-kinase/AKT/molecular target of rapamycin metabolic pathway by primary letrozole-based therapy in human breast cancer.
    Generali D; Fox SB; Brizzi MP; Allevi G; Bonardi S; Aguggini S; Milani M; Bersiga A; Campo L; Dionisio R; Vergoni F; Giardini R; Dogliotti L; Bottini A; Harris AL; Berruti A
    Clin Cancer Res; 2008 May; 14(9):2673-80. PubMed ID: 18451231
    [TBL] [Abstract][Full Text] [Related]  

  • 13. From Rapa Nui to rapamycin: targeting PI3K/Akt/mTOR for cancer therapy.
    Georgakis GV; Younes A
    Expert Rev Anticancer Ther; 2006 Jan; 6(1):131-40. PubMed ID: 16375650
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design and synthesis of novel furoquinoline based inhibitors of multiple targets in the PI3K/Akt-mTOR pathway.
    Lohar MV; Mundada R; Bhonde M; Padgaonkar A; Deore V; Yewalkar N; Bhatia D; Rathos M; Joshi K; Vishwakarma RA; Kumar S
    Bioorg Med Chem Lett; 2008 Jun; 18(12):3603-6. PubMed ID: 18501601
    [TBL] [Abstract][Full Text] [Related]  

  • 15. IGF-1-stimulated protein synthesis in oligodendrocyte progenitors requires PI3K/mTOR/Akt and MEK/ERK pathways.
    Bibollet-Bahena O; Almazan G
    J Neurochem; 2009 Jun; 109(5):1440-51. PubMed ID: 19453943
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Emodin negatively affects the phosphoinositide 3-kinase/AKT signalling pathway: a study on its mechanism of action.
    Olsen BB; Bjørling-Poulsen M; Guerra B
    Int J Biochem Cell Biol; 2007; 39(1):227-37. PubMed ID: 17018259
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutations in the PI3K/PTEN/TSC2 pathway contribute to mammalian target of rapamycin activity and increased translation under hypoxic conditions.
    Kaper F; Dornhoefer N; Giaccia AJ
    Cancer Res; 2006 Feb; 66(3):1561-9. PubMed ID: 16452213
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Statin-dependent suppression of the Akt/mammalian target of rapamycin signaling cascade and programmed cell death 4 up-regulation in renal cell carcinoma.
    Woodard J; Sassano A; Hay N; Platanias LC
    Clin Cancer Res; 2008 Jul; 14(14):4640-9. PubMed ID: 18628479
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Drug discovery approaches targeting the PI3K/Akt pathway in cancer.
    Garcia-Echeverria C; Sellers WR
    Oncogene; 2008 Sep; 27(41):5511-26. PubMed ID: 18794885
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting the phosphatidylinositol-3 kinase/Akt pathway for the treatment of cancer.
    Kim D; Cheng GZ; Lindsley CW; Yang H; Cheng JQ
    Curr Opin Investig Drugs; 2005 Dec; 6(12):1250-8. PubMed ID: 16370391
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.