BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

276 related articles for article (PubMed ID: 16467110)

  • 1. BMS-345541 targets inhibitor of kappaB kinase and induces apoptosis in melanoma: involvement of nuclear factor kappaB and mitochondria pathways.
    Yang J; Amiri KI; Burke JR; Schmid JA; Richmond A
    Clin Cancer Res; 2006 Feb; 12(3 Pt 1):950-60. PubMed ID: 16467110
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Curcumin-induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IkappaB kinase and nuclear factor kappaB activity and are independent of the B-Raf/mitogen-activated/extracellular signal-regulated protein kinase pathway and the Akt pathway.
    Siwak DR; Shishodia S; Aggarwal BB; Kurzrock R
    Cancer; 2005 Aug; 104(4):879-90. PubMed ID: 16007726
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sensitization of melanoma cells for TRAIL-induced apoptosis by BMS-345541 correlates with altered phosphorylation and activation of Bax.
    Berger A; Quast SA; Plötz M; Kammermeier A; Eberle J
    Cell Death Dis; 2013 Jan; 4(1):e477. PubMed ID: 23348591
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular determinants of melanoma malignancy: selecting targets for improved efficacy of chemotherapy.
    Yang J; Zaja-Milatovic S; Thu YM; Lee F; Smykla R; Richmond A
    Mol Cancer Ther; 2009 Mar; 8(3):636-47. PubMed ID: 19276165
    [TBL] [Abstract][Full Text] [Related]  

  • 5. KINK-1, a novel small-molecule inhibitor of IKKbeta, and the susceptibility of melanoma cells to antitumoral treatment.
    Schön M; Wienrich BG; Kneitz S; Sennefelder H; Amschler K; Vöhringer V; Weber O; Stiewe T; Ziegelbauer K; Schön MP
    J Natl Cancer Inst; 2008 Jun; 100(12):862-75. PubMed ID: 18544741
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Constitutive IkappaB kinase activity correlates with nuclear factor-kappaB activation in human melanoma cells.
    Yang J; Richmond A
    Cancer Res; 2001 Jun; 61(12):4901-9. PubMed ID: 11406569
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p65 activity and ZAP-70 status predict the sensitivity of chronic lymphocytic leukemia cells to the selective IkappaB kinase inhibitor BMS-345541.
    López-Guerra M; Roué G; Pérez-Galán P; Alonso R; Villamor N; Montserrat E; Campo E; Colomer D
    Clin Cancer Res; 2009 Apr; 15(8):2767-76. PubMed ID: 19351760
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting IKK/NF-κB pathway reduces infiltration of inflammatory cells and apoptosis after spinal cord injury in rats.
    Han X; Lu M; Wang S; Lv D; Liu H
    Neurosci Lett; 2012 Mar; 511(1):28-32. PubMed ID: 22289688
    [TBL] [Abstract][Full Text] [Related]  

  • 9. IKK inhibitor suppresses epithelial-mesenchymal transition and induces cell death in prostate cancer.
    Ping H; Yang F; Wang M; Niu Y; Xing N
    Oncol Rep; 2016 Sep; 36(3):1658-64. PubMed ID: 27432067
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activity of the selective IκB kinase inhibitor BMS-345541 against T-cell acute lymphoblastic leukemia: involvement of FOXO3a.
    Buontempo F; Chiarini F; Bressanin D; Tabellini G; Melchionda F; Pession A; Fini M; Neri LM; McCubrey JA; Martelli AM
    Cell Cycle; 2012 Jul; 11(13):2467-75. PubMed ID: 22713244
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cell-selective inhibition of NF-κB signaling improves therapeutic index in a melanoma chemotherapy model.
    Enzler T; Sano Y; Choo MK; Cottam HB; Karin M; Tsao H; Park JM
    Cancer Discov; 2011 Nov; 1(6):496-507. PubMed ID: 22389871
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Imiquimod-induced apoptosis of melanoma cells is mediated by ER stress-dependent Noxa induction and enhanced by NF-κB inhibition.
    El-Khattouti A; Selimovic D; Hannig M; Taylor EB; Abd Elmageed ZY; Hassan SY; Haikel Y; Kandil E; Leverkus M; Brodell RT; Megahed M; Hassan M
    J Cell Mol Med; 2016 Feb; 20(2):266-86. PubMed ID: 26578344
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of type I interferon-mediated antiviral action in human glioma cells by the IKK inhibitors BMS-345541 and TPCA-1.
    Du Z; Whitt MA; Baumann J; Garner JM; Morton CL; Davidoff AM; Pfeffer LM
    J Interferon Cytokine Res; 2012 Aug; 32(8):368-77. PubMed ID: 22509977
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of PI3K/Akt/IKK-alpha/NF-kappaB signaling pathway is required for the apoptosis-evasion in human salivary adenoid cystic carcinoma: its inhibition by quercetin.
    Sun ZJ; Chen G; Hu X; Zhang W; Liu Y; Zhu LX; Zhou Q; Zhao YF
    Apoptosis; 2010 Jul; 15(7):850-63. PubMed ID: 20386985
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induction of apoptosis in melanoma A375 cells by a chloroform fraction of Centratherum anthelminticum (L.) seeds involves NF-kappaB, p53 and Bcl-2-controlled mitochondrial signaling pathways.
    Looi CY; Moharram B; Paydar M; Wong YL; Leong KH; Mohamad K; Arya A; Wong WF; Mustafa MR
    BMC Complement Altern Med; 2013 Jul; 13():166. PubMed ID: 23837445
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Isoalantolactone inhibits IKKβ kinase activity to interrupt the NF-κB/COX-2-mediated signaling cascade and induces apoptosis regulated by the mitochondrial translocation of cofilin in glioblastoma.
    Xing JS; Wang X; Lan YL; Lou JC; Ma B; Zhu T; Zhang H; Wang D; Yu Z; Yuan Z; Li XY; Zhang B
    Cancer Med; 2019 Apr; 8(4):1655-1670. PubMed ID: 30740911
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice.
    Burke JR; Pattoli MA; Gregor KR; Brassil PJ; MacMaster JF; McIntyre KW; Yang X; Iotzova VS; Clarke W; Strnad J; Qiu Y; Zusi FC
    J Biol Chem; 2003 Jan; 278(3):1450-6. PubMed ID: 12403772
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cyanidin-3-o-β-Glucoside Induces Megakaryocyte Apoptosis via PI3K/Akt- and MAPKs-Mediated Inhibition of NF-κB Signalling.
    Ya F; Li Q; Wang D; Xie S; Song F; Gallant RC; Tian Z; Wan J; Ling W; Yang Y
    Thromb Haemost; 2018 Jul; 118(7):1215-1229. PubMed ID: 29864778
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lauroside B, a megastigmane glycoside from Laurus nobilis (bay laurel) leaves, induces apoptosis in human melanoma cell lines by inhibiting NF-κB activation.
    Panza E; Tersigni M; Iorizzi M; Zollo F; De Marino S; Festa C; Napolitano M; Castello G; Ialenti A; Ianaro A
    J Nat Prod; 2011 Feb; 74(2):228-33. PubMed ID: 21188975
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nitric Oxide Inhibits NF-κB-mediated Survival Signaling: Possible Role in Overcoming TRAIL Resistance.
    Bauer JA; Lupica JA; Didonato JA; Lindner DJ
    Anticancer Res; 2020 Dec; 40(12):6751-6763. PubMed ID: 33288568
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.