260 related articles for article (PubMed ID: 16468742)
1. Design, total synthesis, and evaluation of novel open-chain epothilone analogues.
Alhamadsheh MM; Hudson RA; Viranga Tillekeratne LM
Org Lett; 2006 Feb; 8(4):685-8. PubMed ID: 16468742
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis, and biological properties of highly potent epothilone B analogues.
Nicolaou KC; Sasmal PK; Rassias G; Reddy MV; Altmann KH; Wartmann M; O'Brate A; Giannakakou P
Angew Chem Int Ed Engl; 2003 Aug; 42(30):3515-20. PubMed ID: 12900969
[No Abstract] [Full Text] [Related]
3. C-15 thiazol-4-yl analogues of (E)-9,10-didehydroepothilone D: synthesis and cytotoxicity.
Hearn BR; Zhang D; Li Y; Myles DC
Org Lett; 2006 Jul; 8(14):3057-9. PubMed ID: 16805551
[TBL] [Abstract][Full Text] [Related]
4. Total synthesis and biological assessment of benzimidazole-based analogues of epothilone A: ambivalent effects on cancer cell growth inhibition.
Cachoux F; Isarno T; Wartmann M; Altmann KH
Chembiochem; 2006 Jan; 7(1):54-7. PubMed ID: 16345113
[No Abstract] [Full Text] [Related]
5. Design, synthesis, and biological evaluation of artificial macrosphelides in the search for new apoptosis-inducing agents.
Matsuya Y; Kobayashi Y; Kawaguchi T; Hori A; Watanabe Y; Ishihara K; Ahmed K; Wei ZL; Yu DY; Zhao QL; Kondo T; Nemoto H
Chemistry; 2009 Jun; 15(23):5799-813. PubMed ID: 19370747
[TBL] [Abstract][Full Text] [Related]
6. Total synthesis of hypermodified epothilone analogs with potent in vitro antitumor activity.
Kuzniewski CN; Gertsch J; Wartmann M; Altmann KH
Org Lett; 2008 Mar; 10(6):1183-6. PubMed ID: 18303900
[TBL] [Abstract][Full Text] [Related]
7. Epothilone analogues with benzimidazole and quinoline side chains: chemical synthesis, antiproliferative activity, and interactions with tubulin.
Dietrich SA; Lindauer R; Stierlin C; Gertsch J; Matesanz R; Notararigo S; Díaz JF; Altmann KH
Chemistry; 2009 Oct; 15(39):10144-57. PubMed ID: 19697384
[TBL] [Abstract][Full Text] [Related]
8. Complex target-oriented total synthesis in the drug discovery process: the discovery of a highly promising family of second generation epothilones.
Rivkin A; Yoshimura F; Gabarda AE; Chou TC; Dong H; Tong WP; Danishefsky SJ
J Am Chem Soc; 2003 Mar; 125(10):2899-901. PubMed ID: 12617656
[TBL] [Abstract][Full Text] [Related]
9. Epothilones as lead structures for the synthesis-based discovery of new chemotypes for microtubule stabilization.
Feyen F; Cachoux F; Gertsch J; Wartmann M; Altmann KH
Acc Chem Res; 2008 Jan; 41(1):21-31. PubMed ID: 18159935
[TBL] [Abstract][Full Text] [Related]
10. Conformation-activity relationships in polyketide natural products: a new perspective on the rational design of epothilone analogues.
Taylor RE; Chen Y; Beatty A; Myles DC; Zhou Y
J Am Chem Soc; 2003 Jan; 125(1):26-7. PubMed ID: 12515494
[TBL] [Abstract][Full Text] [Related]
11. Scaffolds for microtubule inhibition through extensive modification of the epothilone template.
Cachoux F; Isarno T; Wartmann M; Altmann KH
Angew Chem Int Ed Engl; 2005 Dec; 44(45):7469-73. PubMed ID: 16240301
[No Abstract] [Full Text] [Related]
12. Design and total synthesis of a superior family of epothilone analogues, which eliminate xenograft tumors to a nonrelapsable state.
Chou TC; Dong H; Rivkin A; Yoshimura F; Gabarda AE; Cho YS; Tong WP; Danishefsky SJ
Angew Chem Int Ed Engl; 2003 Oct; 42(39):4762-7. PubMed ID: 14562342
[No Abstract] [Full Text] [Related]
13. Application of ring-closing metathesis reactions in the synthesis of epothilones.
Rivkin A; Cho YS; Gabarda AE; Yoshimura F; Danishefsky SJ
J Nat Prod; 2004 Feb; 67(2):139-43. PubMed ID: 14987048
[TBL] [Abstract][Full Text] [Related]
14. Isolation and characterization of new epothilone analogues from recombinant Myxococcus xanthus fermentations.
Starks CM; Zhou Y; Liu F; Licari PJ
J Nat Prod; 2003 Oct; 66(10):1313-7. PubMed ID: 14575429
[TBL] [Abstract][Full Text] [Related]
15. Regioselective synthesis of folate receptor-targeted agents derived from epothilone analogs and folic acid.
Vlahov IR; Vite GD; Kleindl PJ; Wang Y; Santhapuram HK; You F; Howard SJ; Kim SH; Lee FF; Leamon CP
Bioorg Med Chem Lett; 2010 Aug; 20(15):4578-81. PubMed ID: 20594844
[TBL] [Abstract][Full Text] [Related]
16. Design and synthesis of 12-aza-epothilones (azathilones)--"non-natural" natural products with potent anticancer activity.
Feyen F; Gertsch J; Wartmann M; Altmann KH
Angew Chem Int Ed Engl; 2006 Sep; 45(35):5880-5. PubMed ID: 16871640
[No Abstract] [Full Text] [Related]
17. 12,13-Aziridinyl Epothilones. Stereoselective Synthesis of Trisubstituted Olefinic Bonds from Methyl Ketones and Heteroaromatic Phosphonates and Design, Synthesis, and Biological Evaluation of Potent Antitumor Agents.
Nicolaou KC; Rhoades D; Wang Y; Bai R; Hamel E; Aujay M; Sandoval J; Gavrilyuk J
J Am Chem Soc; 2017 May; 139(21):7318-7334. PubMed ID: 28513142
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis, and evaluation of carbamate-substituted analogues of (+)-discodermolide.
Smith AB; Freeze BS; Lamarche MJ; Hirose T; Brouard I; Rucker PV; Xian M; Sundermann KF; Shaw SJ; Burlingame MA; Horwitz SB; Myles DC
Org Lett; 2005 Jan; 7(2):311-4. PubMed ID: 15646985
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and Biological Evaluation of Novel Epothilone B Side Chain Analogues.
Nicolaou KC; Rhoades D; Wang Y; Totokotsopoulos S; Bai R; Hamel E
ChemMedChem; 2015 Dec; 10(12):1974-9. PubMed ID: 26447977
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis, and biological evaluation of simplified analogues of (+)-discodermolide. Additional insights on the importance of the diene, the C7 hydroxyl, and the lactone.
Smith AB; Xian M
Org Lett; 2005 Nov; 7(23):5229-32. PubMed ID: 16268545
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
