BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 16469876)

  • 1. Molecular dissection of Meis1 reveals 2 domains required for leukemia induction and a key role for Hoxa gene activation.
    Mamo A; Krosl J; Kroon E; Bijl J; Thompson A; Mayotte N; Girard S; Bisaillon R; Beslu N; Featherstone M; Sauvageau G
    Blood; 2006 Jul; 108(2):622-9. PubMed ID: 16469876
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the MLL-Rearranged Disease.
    Li Z; Chen P; Su R; Hu C; Li Y; Elkahloun AG; Zuo Z; Gurbuxani S; Arnovitz S; Weng H; Wang Y; Li S; Huang H; Neilly MB; Wang GG; Jiang X; Liu PP; Jin J; Chen J
    Cancer Res; 2016 Feb; 76(3):619-29. PubMed ID: 26747896
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Persistent transactivation by meis1 replaces hox function in myeloid leukemogenesis models: evidence for co-occupancy of meis1-pbx and hox-pbx complexes on promoters of leukemia-associated genes.
    Wang GG; Pasillas MP; Kamps MP
    Mol Cell Biol; 2006 May; 26(10):3902-16. PubMed ID: 16648484
    [TBL] [Abstract][Full Text] [Related]  

  • 4. C-terminal domain of MEIS1 converts PKNOX1 (PREP1) into a HOXA9-collaborating oncoprotein.
    Bisaillon R; Wilhelm BT; Krosl J; Sauvageau G
    Blood; 2011 Oct; 118(17):4682-9. PubMed ID: 21900201
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires interaction with Pbx and a novel function of the Meis1 C-terminus.
    Wang GG; Pasillas MP; Kamps MP
    Blood; 2005 Jul; 106(1):254-64. PubMed ID: 15755900
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Grist for the MLL: how do MLL oncogenic fusion proteins generate leukemia stem cells?
    Somervaille TC; Cleary ML
    Int J Hematol; 2010 Jun; 91(5):735-41. PubMed ID: 20454944
    [TBL] [Abstract][Full Text] [Related]  

  • 7. c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells.
    Hess JL; Bittner CB; Zeisig DT; Bach C; Fuchs U; Borkhardt A; Frampton J; Slany RK
    Blood; 2006 Jul; 108(1):297-304. PubMed ID: 16507773
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A role for MEIS1 in MLL-fusion gene leukemia.
    Kumar AR; Li Q; Hudson WA; Chen W; Sam T; Yao Q; Lund EA; Wu B; Kowal BJ; Kersey JH
    Blood; 2009 Feb; 113(8):1756-8. PubMed ID: 19109563
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential.
    Wong P; Iwasaki M; Somervaille TC; So CW; Cleary ML
    Genes Dev; 2007 Nov; 21(21):2762-74. PubMed ID: 17942707
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9.
    So CW; Karsunky H; Wong P; Weissman IL; Cleary ML
    Blood; 2004 Apr; 103(8):3192-9. PubMed ID: 15070702
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The miR-17∼92 cluster contributes to MLL leukemia through the repression of MEIS1 competitor PKNOX1.
    Mian YA; Zeleznik-Le NJ
    Leuk Res; 2016 Jul; 46():51-60. PubMed ID: 27123834
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HoxA9-mediated immortalization of myeloid progenitors requires functional interactions with TALE cofactors Pbx and Meis.
    Schnabel CA; Jacobs Y; Cleary ML
    Oncogene; 2000 Feb; 19(5):608-16. PubMed ID: 10698505
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Meis1-mediated apoptosis is caspase dependent and can be suppressed by coexpression of HoxA9 in murine and human cell lines.
    Wermuth PJ; Buchberg AM
    Blood; 2005 Feb; 105(3):1222-30. PubMed ID: 15479723
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4 : 11) abnormality.
    Rozovskaia T; Feinstein E; Mor O; Foa R; Blechman J; Nakamura T; Croce CM; Cimino G; Canaani E
    Oncogene; 2001 Feb; 20(7):874-8. PubMed ID: 11314021
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization.
    Zeisig BB; Milne T; García-Cuéllar MP; Schreiner S; Martin ME; Fuchs U; Borkhardt A; Chanda SK; Walker J; Soden R; Hess JL; Slany RK
    Mol Cell Biol; 2004 Jan; 24(2):617-28. PubMed ID: 14701735
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice.
    Moskow JJ; Bullrich F; Huebner K; Daar IO; Buchberg AM
    Mol Cell Biol; 1995 Oct; 15(10):5434-43. PubMed ID: 7565694
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interaction of MLL amino terminal sequences with menin is required for transformation.
    Caslini C; Yang Z; El-Osta M; Milne TA; Slany RK; Hess JL
    Cancer Res; 2007 Aug; 67(15):7275-83. PubMed ID: 17671196
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Down-regulation of homeobox genes MEIS1 and HOXA in MLL-rearranged acute leukemia impairs engraftment and reduces proliferation.
    Orlovsky K; Kalinkovich A; Rozovskaia T; Shezen E; Itkin T; Alder H; Ozer HG; Carramusa L; Avigdor A; Volinia S; Buchberg A; Mazo A; Kollet O; Largman C; Croce CM; Nakamura T; Lapidot T; Canaani E
    Proc Natl Acad Sci U S A; 2011 May; 108(19):7956-61. PubMed ID: 21518888
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MLL is essential for NUP98-HOXA9-induced leukemia.
    Shima Y; Yumoto M; Katsumoto T; Kitabayashi I
    Leukemia; 2017 Oct; 31(10):2200-2210. PubMed ID: 28210005
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nup98-HoxA9 immortalizes myeloid progenitors, enforces expression of Hoxa9, Hoxa7 and Meis1, and alters cytokine-specific responses in a manner similar to that induced by retroviral co-expression of Hoxa9 and Meis1.
    Calvo KR; Sykes DB; Pasillas MP; Kamps MP
    Oncogene; 2002 Jun; 21(27):4247-56. PubMed ID: 12082612
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.