BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

59 related articles for article (PubMed ID: 1647085)

  • 1. [Anti-retroviral activity and molecular-biochemical action mechanism of 2',3'-dideoxynucleoside analogs and 9-(2-phosphonylmethoxyethyl) purine derivatives].
    Balzarini J
    Verh K Acad Geneeskd Belg; 1991; 53(1):61-98. PubMed ID: 1647085
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives.
    Balzarini J
    Pharm World Sci; 1994 Apr; 16(2):113-26. PubMed ID: 8032337
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 2',3'-Dideoxycytidine: regulation of its metabolism and anti-retroviral potency by natural pyrimidine nucleosides and by inhibitors of pyrimidine nucleotide synthesis.
    Balzarini J; Cooney DA; Dalal M; Kang GJ; Cupp JE; DeClercq E; Broder S; Johns DG
    Mol Pharmacol; 1987 Dec; 32(6):798-806. PubMed ID: 2826994
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2',3'-Dideoxycytidine toxicity in cultured human CEM T lymphoblasts: effects of combination with 3'-azido-3'-deoxythymidine and thymidine.
    Törnevik Y; Eriksson S
    Mol Pharmacol; 1990 Aug; 38(2):237-43. PubMed ID: 2166904
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A human T lymphoid cell variant resistant to the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxyethyl)adenine shows a unique combination of a phosphorylation defect and increased efflux of the agent.
    Robbins BL; Connelly MC; Marshall DR; Srinivas RV; Fridland A
    Mol Pharmacol; 1995 Feb; 47(2):391-7. PubMed ID: 7870049
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Development of new potent and selective agents against HIV (human immunodeficiency virus).
    Pauwels R; Schols D
    Verh K Acad Geneeskd Belg; 1991; 53(6):629-55. PubMed ID: 1816706
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Anti-retrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in vivo increases when it is less frequently administered.
    Balzarini J; Naesens L; De Clercq E
    Int J Cancer; 1990 Aug; 46(2):337-40. PubMed ID: 2384280
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anti-retrovirus activity of 3'-fluoro- and 3'-azido-substituted pyrimidine 2',3'-dideoxynucleoside analogues.
    Balzarini J; Baba M; Pauwels R; Herdewijn P; De Clerq E
    Biochem Pharmacol; 1988 Jul; 37(14):2847-56. PubMed ID: 2840080
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The in vitro and in vivo anti-retrovirus activity, and intracellular metabolism of 3'-azido-2',3'-dideoxythymidine and 2',3'-dideoxycytidine are highly dependent on the cell species.
    Balzarini J; Pauwels R; Baba M; Herdewijn P; de Clercq E; Broder S; Johns DG
    Biochem Pharmacol; 1988 Mar; 37(5):897-903. PubMed ID: 2830886
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pharmacokinetics in mice of the anti-retrovirus agent 9-(2-phosphonylmethoxyethyl)adenine.
    Naesens L; Balzarini J; De Clercq E
    Drug Metab Dispos; 1992; 20(5):747-52. PubMed ID: 1358582
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and antiretroviral evaluation of new alkoxy and aryloxy phosphate derivatives of 3'-azido-3'-deoxythymidine.
    Tsotinis A; Calogeropoulou T; Koufaki M; Souli C; Balzarini J; De Clercq E; Makriyannis A
    J Med Chem; 1996 Aug; 39(17):3418-22. PubMed ID: 8765527
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antiretroviral activity and pharmacokinetics in mice of oral bis(pivaloyloxymethyl)-9-(2-phosphonylmethoxyethyl)adenine, the bis(pivaloyloxymethyl) ester prodrug of 9-(2-phosphonylmethoxyethyl)adenine.
    Naesens L; Balzarini J; Bischofberger N; De Clercq E
    Antimicrob Agents Chemother; 1996 Jan; 40(1):22-8. PubMed ID: 8787873
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of visna virus replication by 2',3'-dideoxynucleosides and acyclic nucleoside phosphonate analogs.
    Thormar H; Balzarini J; Holy A; Jindrich J; Rosenberg I; Debyser Z; Desmyter J; De Clercq E
    Antimicrob Agents Chemother; 1993 Dec; 37(12):2540-4. PubMed ID: 7509142
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cell-protecting effect against herpes simplex virus-1 and cellular metabolism of 9-(2-phosphonylmethoxyethyl)adenine in HeLa S3 cells.
    Cerny J; Foster SA; Cheng YC
    Mol Pharmacol; 1992 Sep; 42(3):537-44. PubMed ID: 1328849
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base.
    Holý A; Günter J; Dvoráková H; Masojídková M; Andrei G; Snoeck R; Balzarini J; De Clercq E
    J Med Chem; 1999 Jun; 42(12):2064-86. PubMed ID: 10377214
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of a yeast retrotransposon-based system useful for screening of potentially active anti-retroviral compounds.
    Sanguinetti M; Posteraro B; Rossolini GM; Satta G
    New Microbiol; 1995 Apr; 18(2):117-25. PubMed ID: 7603338
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Suppression of feline immunodeficiency virus infection in vivo by 9-(2-phosphonomethoxyethyl)adenine.
    Egberink H; Borst M; Niphuis H; Balzarini J; Neu H; Schellekens H; De Clercq E; Horzinek M; Koolen M
    Proc Natl Acad Sci U S A; 1990 Apr; 87(8):3087-91. PubMed ID: 2158102
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolic pathways for activation of the antiviral agent 9-(2-phosphonylmethoxyethyl)adenine in human lymphoid cells.
    Robbins BL; Greenhaw J; Connelly MC; Fridland A
    Antimicrob Agents Chemother; 1995 Oct; 39(10):2304-8. PubMed ID: 8619586
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Factors determining the activity of 2',3'-dideoxynucleosides in suppressing human immunodeficiency virus in vitro.
    Hao Z; Cooney DA; Hartman NR; Perno CF; Fridland A; DeVico AL; Sarngadharan MG; Broder S; Johns DG
    Mol Pharmacol; 1988 Oct; 34(4):431-5. PubMed ID: 2459590
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Spectrum of antiviral activity and mechanism of action of zidovudine. An overview.
    Furman PA; Barry DW
    Am J Med; 1988 Aug; 85(2A):176-81. PubMed ID: 3044082
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 3.