BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 16477632)

  • 1. Analysis of fumarate hydratase mutations in a population-based series of early onset uterine leiomyosarcoma patients.
    Ylisaukko-oja SK; Kiuru M; Lehtonen HJ; Lehtonen R; Pukkala E; Arola J; Launonen V; Aaltonen LA
    Int J Cancer; 2006 Jul; 119(2):283-7. PubMed ID: 16477632
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors.
    Lehtonen R; Kiuru M; Vanharanta S; Sjöberg J; Aaltonen LM; Aittomäki K; Arola J; Butzow R; Eng C; Husgafvel-Pursiainen K; Isola J; Järvinen H; Koivisto P; Mecklin JP; Peltomäki P; Salovaara R; Wasenius VM; Karhu A; Launonen V; Nupponen NN; Aaltonen LA
    Am J Pathol; 2004 Jan; 164(1):17-22. PubMed ID: 14695314
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hereditary leiomyomatosis and renal cell cancer in families referred for fumarate hydratase germline mutation analysis.
    Smit DL; Mensenkamp AR; Badeloe S; Breuning MH; Simon ME; van Spaendonck KY; Aalfs CM; Post JG; Shanley S; Krapels IP; Hoefsloot LH; van Moorselaar RJ; Starink TM; Bayley JP; Frank J; van Steensel MA; Menko FH
    Clin Genet; 2011 Jan; 79(1):49-59. PubMed ID: 20618355
    [TBL] [Abstract][Full Text] [Related]  

  • 4. No evidence for epigenetic inactivation of fumarate hydratase in leiomyomas and leiomyosarcomas.
    Barker KT; Spendlove HE; Banu NS; Bridge JA; Fisher C; Shipley J; Garrett M; Manyonda I; Houlston RS
    Cancer Lett; 2006 Apr; 235(1):136-40. PubMed ID: 15949892
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Few FH mutations in sporadic counterparts of tumor types observed in hereditary leiomyomatosis and renal cell cancer families.
    Kiuru M; Lehtonen R; Arola J; Salovaara R; Järvinen H; Aittomäki K; Sjöberg J; Visakorpi T; Knuutila S; Isola J; Delahunt B; Herva R; Launonen V; Karhu A; Aaltonen LA
    Cancer Res; 2002 Aug; 62(16):4554-7. PubMed ID: 12183404
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Morphologic and molecular characteristics of uterine leiomyomas in hereditary leiomyomatosis and renal cancer (HLRCC) syndrome.
    Sanz-Ortega J; Vocke C; Stratton P; Linehan WM; Merino MJ
    Am J Surg Pathol; 2013 Jan; 37(1):74-80. PubMed ID: 23211287
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Morphology and Immunohistochemistry for 2SC and FH Aid in Detection of Fumarate Hydratase Gene Aberrations in Uterine Leiomyomas From Young Patients.
    Joseph NM; Solomon DA; Frizzell N; Rabban JT; Zaloudek C; Garg K
    Am J Surg Pathol; 2015 Nov; 39(11):1529-39. PubMed ID: 26457356
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Prevalence of somatic and germline mutations of Fumarate hydratase in uterine leiomyomas from young patients.
    Liu C; Dillon J; Beavis AL; Liu Y; Lombardo K; Fader AN; Hung CF; Wu TC; Vang R; Garcia JE; Xing D
    Histopathology; 2020 Feb; 76(3):354-365. PubMed ID: 31564060
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prospective Detection of Germline Mutation of Fumarate Hydratase in Women With Uterine Smooth Muscle Tumors Using Pathology-based Screening to Trigger Genetic Counseling for Hereditary Leiomyomatosis Renal Cell Carcinoma Syndrome: A 5-Year Single Institutional Experience.
    Rabban JT; Chan E; Mak J; Zaloudek C; Garg K
    Am J Surg Pathol; 2019 May; 43(5):639-655. PubMed ID: 30741757
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fumarate Hydratase-deficient Uterine Leiomyomas Occur in Both the Syndromic and Sporadic Settings.
    Harrison WJ; Andrici J; Maclean F; Madadi-Ghahan R; Farzin M; Sioson L; Toon CW; Clarkson A; Watson N; Pickett J; Field M; Crook A; Tucker K; Goodwin A; Anderson L; Srinivasan B; Grossmann P; Martinek P; Ondič O; Hes O; Trpkov K; Clifton-Bligh RJ; Dwight T; Gill AJ
    Am J Surg Pathol; 2016 May; 40(5):599-607. PubMed ID: 26574848
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Missense mutations in fumarate hydratase in multiple cutaneous and uterine leiomyomatosis and renal cell cancer.
    Alam NA; Olpin S; Rowan A; Kelsell D; Leigh IM; Tomlinson IP; Weaver T
    J Mol Diagn; 2005 Oct; 7(4):437-43. PubMed ID: 16237213
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Low frequency of somatic mutations in the FH/multiple cutaneous leiomyomatosis gene in sporadic leiomyosarcomas and uterine leiomyomas.
    Barker KT; Bevan S; Wang R; Lu YJ; Flanagan AM; Bridge JA; Fisher C; Finlayson CJ; Shipley J; Houlston RS
    Br J Cancer; 2002 Aug; 87(4):446-8. PubMed ID: 12177782
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reassessing the clinical spectrum associated with hereditary leiomyomatosis and renal cell carcinoma syndrome in French FH mutation carriers.
    Muller M; Ferlicot S; Guillaud-Bataille M; Le Teuff G; Genestie C; Deveaux S; Slama A; Poulalhon N; Escudier B; Albiges L; Soufir N; Avril MF; Gardie B; Saldana C; Allory Y; Gimenez-Roqueplo AP; Bressac-de Paillerets B; Richard S; Benusiglio PR
    Clin Genet; 2017 Dec; 92(6):606-615. PubMed ID: 28300276
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Association of germline mutations in the fumarate hydratase gene and uterine fibroids in women with hereditary leiomyomatosis and renal cell cancer.
    Stewart L; Glenn GM; Stratton P; Goldstein AM; Merino MJ; Tucker MA; Linehan WM; Toro JR
    Arch Dermatol; 2008 Dec; 144(12):1584-92. PubMed ID: 19075141
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genetic and functional analyses of FH mutations in multiple cutaneous and uterine leiomyomatosis, hereditary leiomyomatosis and renal cancer, and fumarate hydratase deficiency.
    Alam NA; Rowan AJ; Wortham NC; Pollard PJ; Mitchell M; Tyrer JP; Barclay E; Calonje E; Manek S; Adams SJ; Bowers PW; Burrows NP; Charles-Holmes R; Cook LJ; Daly BM; Ford GP; Fuller LC; Hadfield-Jones SE; Hardwick N; Highet AS; Keefe M; MacDonald-Hull SP; Potts ED; Crone M; Wilkinson S; Camacho-Martinez F; Jablonska S; Ratnavel R; MacDonald A; Mann RJ; Grice K; Guillet G; Lewis-Jones MS; McGrath H; Seukeran DC; Morrison PJ; Fleming S; Rahman S; Kelsell D; Leigh I; Olpin S; Tomlinson IP
    Hum Mol Genet; 2003 Jun; 12(11):1241-52. PubMed ID: 12761039
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Strong family history of uterine leiomyomatosis warrants fumarate hydratase mutation screening.
    Tolvanen J; Uimari O; Ryynänen M; Aaltonen LA; Vahteristo P
    Hum Reprod; 2012 Jun; 27(6):1865-9. PubMed ID: 22473397
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Increased risk of cancer in patients with fumarate hydratase germline mutation.
    Lehtonen HJ; Kiuru M; Ylisaukko-Oja SK; Salovaara R; Herva R; Koivisto PA; Vierimaa O; Aittomäki K; Pukkala E; Launonen V; Aaltonen LA
    J Med Genet; 2006 Jun; 43(6):523-6. PubMed ID: 16155190
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fumarate hydratase gene mutation in two young patients with sporadic uterine fibroids.
    Kubinova K; Tesarova M; Hansikova H; Vesela K; Kuzel D; Mara M
    J Obstet Gynaecol Res; 2013 Jan; 39(1):410-4. PubMed ID: 22764886
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutation screening of fumarate hydratase by multiplex ligation-dependent probe amplification: detection of exonic deletion in a patient with leiomyomatosis and renal cell cancer.
    Ahvenainen T; Lehtonen HJ; Lehtonen R; Vahteristo P; Aittomäki K; Baynam G; Dommering C; Eng C; Gruber SB; Grönberg H; Harvima R; Herva R; Hietala M; Kujala M; Kääriäinen H; Sunde L; Vierimaa O; Pollard PJ; Tomlinson IP; Björck E; Aaltonen LA; Launonen V
    Cancer Genet Cytogenet; 2008 Jun; 183(2):83-8. PubMed ID: 18503824
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Germline fumarate hydratase mutations in patients with ovarian mucinous cystadenoma.
    Ylisaukko-oja SK; Cybulski C; Lehtonen R; Kiuru M; Matyjasik J; Szymañska A; Szymañska-Pasternak J; Dyrskjot L; Butzow R; Orntoft TF; Launonen V; Lubiñski J; Aaltonen LA
    Eur J Hum Genet; 2006 Jul; 14(7):880-3. PubMed ID: 16639410
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.