393 related articles for article (PubMed ID: 16480280)
1. Design, synthesis, and biological evaluation of pyrrolo[2,1-c][1,4]benzodiazepine and indole conjugates as anticancer agents.
Wang JJ; Shen YK; Hu WP; Hsieh MC; Lin FL; Hsu MK; Hsu MH
J Med Chem; 2006 Feb; 49(4):1442-9. PubMed ID: 16480280
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and antitumor activity of novel enediyne-linked pyrrolo[2,1-c][1,4]benzodiazepine hybrids.
Hu WP; Liang JJ; Kao CL; Chen YC; Chen CY; Tsai FY; Wu MJ; Chang LS; Chen YL; Wang JJ
Bioorg Med Chem; 2009 Feb; 17(3):1172-80. PubMed ID: 19131253
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and biological evaluation of thiobenzanilides as anticancer agents.
Hu WP; Yu HS; Chen YR; Tsai YM; Chen YK; Liao CC; Chang LS; Wang JJ
Bioorg Med Chem; 2008 May; 16(9):5295-302. PubMed ID: 18359635
[TBL] [Abstract][Full Text] [Related]
4. Quinazolinone linked pyrrolo[2,1-c][1,4]benzodiazepine (PBD) conjugates: Design, synthesis and biological evaluation as potential anticancer agents.
Kamal A; Vijaya Bharathi E; Janaki Ramaiah M; Dastagiri D; Surendranadha Reddy J; Viswanath A; Sultana F; Pushpavalli SN; Pal-Bhadra M; Srivastava HK; Narahari Sastry G; Juvekar A; Sen S; Zingde S
Bioorg Med Chem; 2010 Jan; 18(2):526-42. PubMed ID: 20031423
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of C8-linked pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole conjugates with remarkable DNA-binding affinity.
Kamal A; Ramulu P; Srinivas O; Ramesh G; Kumar PP
Bioorg Med Chem Lett; 2004 Sep; 14(18):4791-4. PubMed ID: 15324909
[TBL] [Abstract][Full Text] [Related]
6. DC-81-Indole conjugate agent induces mitochondria mediated apoptosis in human melanoma A375 cells.
Hu WP; Yu HS; Sung PJ; Tsai FY; Shen YK; Chang LS; Wang JJ
Chem Res Toxicol; 2007 Jun; 20(6):905-12. PubMed ID: 17530784
[TBL] [Abstract][Full Text] [Related]
7. Design and synthesis of benzo[c,d]indolone-pyrrolobenzodiazepine conjugates as potential anticancer agents.
Kamal A; Ramakrishna G; Lakshma Nayak V; Raju P; Subba Rao AV; Viswanath A; Vishnuvardhan MV; Ramakrishna S; Srinivas G
Bioorg Med Chem; 2012 Jan; 20(2):789-800. PubMed ID: 22209733
[TBL] [Abstract][Full Text] [Related]
8. Linker length modulates DNA cross-linking reactivity and cytotoxic potency of C8/C8' ether-linked C2-exo-unsaturated pyrrolo[2,1-c][1,4]benzodiazepine (PBD) dimers.
Gregson SJ; Howard PW; Gullick DR; Hamaguchi A; Corcoran KE; Brooks NA; Hartley JA; Jenkins TC; Patel S; Guille MJ; Thurston DE
J Med Chem; 2004 Feb; 47(5):1161-74. PubMed ID: 14971896
[TBL] [Abstract][Full Text] [Related]
9. Synthesis of aryl-substituted naphthalene-linked pyrrolobenzodiazepine conjugates as potential anticancer agents with apoptosis-inducing ability.
Kamal A; Reddy MK; Ramaiah MJ; Srikanth YV; Rajender ; Reddy VS; Kumar GB; Pushpavalli SN; Bag I; Juvekar A; Sen S; Zingde SM; Pal-Bhadra M
ChemMedChem; 2011 Sep; 6(9):1665-79. PubMed ID: 21732540
[TBL] [Abstract][Full Text] [Related]
10. Synthesis, DNA binding, and cytotoxicity studies of pyrrolo[2,1-c][1,4]benzodiazepine-anthraquinone conjugates.
Kamal A; Ramu R; Tekumalla V; Khanna GB; Barkume MS; Juvekar AS; Zingde SM
Bioorg Med Chem; 2007 Nov; 15(22):6868-75. PubMed ID: 17822905
[TBL] [Abstract][Full Text] [Related]
11. A DC-81-indole conjugate agent suppresses melanoma A375 cell migration partially via interrupting VEGF production and stromal cell-derived factor-1α-mediated signaling.
Hsieh MC; Hu WP; Yu HS; Wu WC; Chang LS; Kao YH; Wang JJ
Toxicol Appl Pharmacol; 2011 Sep; 255(2):150-9. PubMed ID: 21708181
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and biological evaluation of pyrrolo[2,1-c][1,4]benzodiazepine (PBD) C8 cyclic amine conjugates.
Masterson LA; Croker SJ; Jenkins TC; Howard PW; Thurston DE
Bioorg Med Chem Lett; 2004 Feb; 14(4):901-4. PubMed ID: 15012990
[TBL] [Abstract][Full Text] [Related]
13. Solid-phase synthesis of new pyrrolobenzodiazepine-chalcone conjugates: DNA-binding affinity and anticancer activity.
Kamal A; Shankaraiah N; Prabhakar S; Reddy ChR; Markandeya N; Reddy KL; Devaiah V
Bioorg Med Chem Lett; 2008 Apr; 18(7):2434-9. PubMed ID: 18325766
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, anticancer activity and apoptosis inducing ability of anthranilamide-PBD conjugates.
Kamal A; Vijaya Bharathi E; Janaki Ramaiah M; Surendranadha Reddy J; Dastagiri D; Viswanath A; Sultana F; Pushpavalli SN; Pal-Bhadra M; Juvekar A; Sen S; Zingde S
Bioorg Med Chem Lett; 2010 Jun; 20(11):3310-3. PubMed ID: 20444601
[TBL] [Abstract][Full Text] [Related]
15. Synthesis, DNA-binding abilities and anticancer activities of triazole-pyrrolo[2,1-c][1,4]benzodiazepines hybrid scaffolds.
Chen CY; Lee PH; Lin YY; Yu WT; Hu WP; Hsu CC; Lin YT; Chang LS; Hsiao CT; Wang JJ; Chung MI
Bioorg Med Chem Lett; 2013 Dec; 23(24):6854-9. PubMed ID: 24161833
[TBL] [Abstract][Full Text] [Related]
16. Synthesis, DNA-binding ability and evaluation of antitumour activity of triazolo[1,2,4]benzothiadiazine linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates.
Kamal A; Khan MN; Srikanth YV; Reddy KS; Juvekar A; Sen S; Kurian N; Zingde S
Bioorg Med Chem; 2008 Aug; 16(16):7804-10. PubMed ID: 18657979
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis, and biophysical and biological evaluation of a series of pyrrolobenzodiazepine-poly(N-methylpyrrole) conjugates.
Wells G; Martin CR; Howard PW; Sands ZA; Laughton CA; Tiberghien A; Woo CK; Masterson LA; Stephenson MJ; Hartley JA; Jenkins TC; Shnyder SD; Loadman PM; Waring MJ; Thurston DE
J Med Chem; 2006 Sep; 49(18):5442-61. PubMed ID: 16942018
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis and biological evaluation of 3,5-diaryl-isoxazoline/isoxazole-pyrrolobenzodiazepine conjugates as potential anticancer agents.
Kamal A; Reddy JS; Ramaiah MJ; Dastagiri D; Bharathi EV; Azhar MA; Sultana F; Pushpavalli SN; Pal-Bhadra M; Juvekar A; Sen S; Zingde S
Eur J Med Chem; 2010 Sep; 45(9):3924-37. PubMed ID: 20557981
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and in vitro cytotoxicity studies of novel pyrrolo[2,1-c][1,4]benzodiazepine (PBD)--polymade conjugates and 2,2'-PBD dimers.
Reddy BS; Damayanthi Y; Reddy BS; Lown JW
Anticancer Drug Des; 2000 Jun; 15(3):225-38. PubMed ID: 11049090
[TBL] [Abstract][Full Text] [Related]
20. Synthesis of 1,2,3-triazole-linked pyrrolobenzodiazepine conjugates employing 'click' chemistry: DNA-binding affinity and anticancer activity.
Kamal A; Shankaraiah N; Devaiah V; Laxma Reddy K; Juvekar A; Sen S; Kurian N; Zingde S
Bioorg Med Chem Lett; 2008 Feb; 18(4):1468-73. PubMed ID: 18207392
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
