BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

102 related articles for article (PubMed ID: 16487066)

  • 21. Characterization of the indole-3-glycerol phosphate synthase from Pseudomonas aeruginosa PAO1.
    Gerth ML; Nigon LV; Patrick WM
    Protein J; 2012 Jun; 31(5):359-65. PubMed ID: 22555873
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Kinetic mechanism of indole-3-glycerol phosphate synthase.
    Schlee S; Dietrich S; Kurćon T; Delaney P; Goodey NM; Sterner R
    Biochemistry; 2013 Jan; 52(1):132-42. PubMed ID: 23214473
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Development of ssDNA aptamers as potent inhibitors of Mycobacterium tuberculosis acetohydroxyacid synthase.
    Baig IA; Moon JY; Lee SC; Ryoo SW; Yoon MY
    Biochim Biophys Acta; 2015 Oct; 1854(10 Pt A):1338-50. PubMed ID: 25988243
    [TBL] [Abstract][Full Text] [Related]  

  • 24. A high-throughput screen against pantothenate synthetase (PanC) identifies 3-biphenyl-4-cyanopyrrole-2-carboxylic acids as a new class of inhibitor with activity against Mycobacterium tuberculosis.
    Kumar A; Casey A; Odingo J; Kesicki EA; Abrahams G; Vieth M; Masquelin T; Mizrahi V; Hipskind PA; Sherman DR; Parish T
    PLoS One; 2013; 8(11):e72786. PubMed ID: 24244263
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis.
    Riccardi G; Pasca MR; Chiarelli LR; Manina G; Mattevi A; Binda C
    Appl Microbiol Biotechnol; 2013 Oct; 97(20):8841-8. PubMed ID: 24037308
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Computational study of the ground state of thermophilic indole glycerol phosphate synthase: structural alterations at the active site with temperature.
    Mazumder-Shivakumar D; Kahn K; Bruice TC
    J Am Chem Soc; 2004 May; 126(19):5936-7. PubMed ID: 15137737
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Inhibition studies of Mycobacterium tuberculosis salicylate synthase (MbtI).
    Manos-Turvey A; Bulloch EM; Rutledge PJ; Baker EN; Lott JS; Payne RJ
    ChemMedChem; 2010 Jul; 5(7):1067-79. PubMed ID: 20512795
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A conserved folding nucleus sculpts the free energy landscape of bacterial and archaeal orthologs from a divergent TIM barrel family.
    Jain R; Muneeruddin K; Anderson J; Harms MJ; Shaffer SA; Matthews CR
    Proc Natl Acad Sci U S A; 2021 Apr; 118(17):. PubMed ID: 33875592
    [TBL] [Abstract][Full Text] [Related]  

  • 29. New Chromane-Based Derivatives as Inhibitors of
    Pini E; Poli G; Tuccinardi T; Chiarelli LR; Mori M; Gelain A; Costantino L; Villa S; Meneghetti F; Barlocco D
    Molecules; 2018 Jun; 23(7):. PubMed ID: 29933627
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Functional shikimate dehydrogenase from Mycobacterium tuberculosis H37Rv: purification and characterization.
    Fonseca IO; Magalhães ML; Oliveira JS; Silva RG; Mendes MA; Palma MS; Santos DS; Basso LA
    Protein Expr Purif; 2006 Apr; 46(2):429-37. PubMed ID: 16298142
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Structure-based screening and molecular dynamics simulations offer novel natural compounds as potential inhibitors of Mycobacterium tuberculosis isocitrate lyase.
    Shukla R; Shukla H; Sonkar A; Pandey T; Tripathi T
    J Biomol Struct Dyn; 2018 Jun; 36(8):2045-2057. PubMed ID: 28605994
    [TBL] [Abstract][Full Text] [Related]  

  • 32. 2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1.
    Neres J; Hartkoorn RC; Chiarelli LR; Gadupudi R; Pasca MR; Mori G; Venturelli A; Savina S; Makarov V; Kolly GS; Molteni E; Binda C; Dhar N; Ferrari S; Brodin P; Delorme V; Landry V; de Jesus Lopes Ribeiro AL; Farina D; Saxena P; Pojer F; Carta A; Luciani R; Porta A; Zanoni G; De Rossi E; Costi MP; Riccardi G; Cole ST
    ACS Chem Biol; 2015 Mar; 10(3):705-14. PubMed ID: 25427196
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Cloning, expression and characterization of histidine-tagged biotin synthase of Mycobacterium tuberculosis.
    Magwamba CC; Rukseree K; Palittapongarnpim P
    Tuberculosis (Edinb); 2016 May; 98():42-9. PubMed ID: 27156617
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Integration of ligand and structure based approaches for identification of novel MbtI inhibitors in Mycobacterium tuberculosis and molecular dynamics simulation studies.
    Maganti L; Grandhi P; Ghoshal N
    J Mol Graph Model; 2016 Nov; 70():14-22. PubMed ID: 27639087
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Characterization of acetohydroxyacid synthase from Mycobacterium tuberculosis and the identification of its new inhibitor from the screening of a chemical library.
    Choi KJ; Yu YG; Hahn HG; Choi JD; Yoon MY
    FEBS Lett; 2005 Aug; 579(21):4903-10. PubMed ID: 16111681
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Correlation of fitness landscapes from three orthologous TIM barrels originates from sequence and structure constraints.
    Chan YH; Venev SV; Zeldovich KB; Matthews CR
    Nat Commun; 2017 Mar; 8():14614. PubMed ID: 28262665
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Detection of soluble co-factor dependent protein expression in vivo: application to the 4'-phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis.
    Rottier K; Faille A; Prudhomme T; Leblanc C; Chalut C; Cabantous S; Guilhot C; Mourey L; Pedelacq JD
    J Struct Biol; 2013 Sep; 183(3):320-328. PubMed ID: 23916562
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Purification and characterization of the Mycobacterium tuberculosis FabD2, a novel malonyl-CoA:AcpM transacylase of fatty acid synthase.
    Huang YS; Ge J; Zhang HM; Lei JQ; Zhang XL; Wang HH
    Protein Expr Purif; 2006 Feb; 45(2):393-9. PubMed ID: 16112872
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Glutamate Racemase Is the Primary Target of β-Chloro-d-Alanine in Mycobacterium tuberculosis.
    Prosser GA; Rodenburg A; Khoury H; de Chiara C; Howell S; Snijders AP; de Carvalho LP
    Antimicrob Agents Chemother; 2016 Oct; 60(10):6091-9. PubMed ID: 27480853
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis and evaluation of C-5 modified 2'-deoxyuridine monophosphates as inhibitors of M. tuberculosis thymidylate synthase.
    Alexandrova LA; Chekhov VO; Shmalenyuk ER; Kochetkov SN; El-Asrar RA; Herdewijn P
    Bioorg Med Chem; 2015 Nov; 23(22):7131-7. PubMed ID: 26482569
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.